MAPK14 Antikörper (C-Term)
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- Target Alle MAPK14 Antikörper anzeigen
- MAPK14 (Mitogen-Activated Protein Kinase 14 (MAPK14))
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Bindungsspezifität
- C-Term
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Reaktivität
- Human, Maus, Ratte, Kaninchen, Rind (Kuh), Schwein, Schaf, Pferd
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser MAPK14 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC)
- Sequenz
- YHDPDDEPVA DPYDQSFESR DLLIDEWKSL TYDEVISFVP PPLDQEEMES
- Homologie
- Cow: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%
- Produktmerkmale
- This is a rabbit polyclonal antibody against MAPK14. It was validated on Western Blot and immunohistochemistry.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the C terminal region of human MAPK14
- Top Product
- Discover our top product MAPK14 Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 360 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- MAPK14 (Mitogen-Activated Protein Kinase 14 (MAPK14))
- Andere Bezeichnung
- MAPK14 (MAPK14 Produkte)
- Synonyme
- CSBP antikoerper, CSBP1 antikoerper, CSBP2 antikoerper, CSPB1 antikoerper, EXIP antikoerper, Mxi2 antikoerper, PRKM14 antikoerper, PRKM15 antikoerper, RK antikoerper, SAPK2A antikoerper, p38 antikoerper, p38ALPHA antikoerper, CRK1 antikoerper, Csbp1 antikoerper, Csbp2 antikoerper, Exip antikoerper, Hog antikoerper, Prkm14 antikoerper, Prkm15 antikoerper, Sapk2A antikoerper, p38Hog antikoerper, p38alpha antikoerper, p38b antikoerper, zp38b antikoerper, MAPK14 antikoerper, 186F5S antikoerper, BG:DS00797.3 antikoerper, CG7393 antikoerper, D-p38 antikoerper, D-p38 MAPK antikoerper, D-p38b antikoerper, Dm p38b antikoerper, Dmel\\CG7393 antikoerper, Dmp38b antikoerper, Dp38 antikoerper, Dp38b antikoerper, ESTS:186F5S antikoerper, Mpk34C antikoerper, anon-sts23 antikoerper, dp38b antikoerper, p38 MAPK antikoerper, p38 beta antikoerper, p38B antikoerper, p38Kb antikoerper, p38beta antikoerper, Crk1 antikoerper, p38-alpha antikoerper, p38MAPK antikoerper, p38a antikoerper, csbp antikoerper, mapk14a antikoerper, mxi2 antikoerper, sapk2 antikoerper, sapk2a antikoerper, AP22.98 antikoerper, AP22_98 antikoerper, ATMPK14 antikoerper, mitogen-activated protein kinase 14 antikoerper, SAPK2a antikoerper, MAP kinase 14A antikoerper, MAP kinase p38a antikoerper, MAPK 14A antikoerper, fk28c03 antikoerper, hm:zeh1243 antikoerper, wu:fk28c03 antikoerper, zp38a antikoerper, P38C-CRK antikoerper, mitogen-activated protein kinase 14 antikoerper, mitogen activated protein kinase 14 antikoerper, mitogen-activated protein kinase 14b antikoerper, p38b MAP kinase antikoerper, mitogen-activated protein kinase 14 S homeolog antikoerper, mitogen-activated protein kinase 14a antikoerper, CRK proto-oncogene, adaptor protein antikoerper, MAPK14 antikoerper, Mapk14 antikoerper, mapk14b antikoerper, p38b antikoerper, mapk14.S antikoerper, MPK14 antikoerper, mapk14a antikoerper, CRK antikoerper
- Hintergrund
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MAPK14 encodes a protein which is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response.
Alias Symbols: RK, p38, CSBP, EXIP, Mxi2, CSBP1, CSBP2, CSPB1, PRKM14, PRKM15, SAPK2A, p38ALPHA
Protein Interaction Partner: MAPKAPK2, ATF2, PDX1, UBC, MARCKSL1, MAP2K3, MAPK14, ATF6, TCEAL1, USP11, PTPN11, OXCT1, NME1, WDR1, HSPD1, TYMS, ADSS, IQGAP1, MKNK1, MAPKAPK3, CNBP, AKT1, CCDC8, OBSL1, RRP1B, RPS6KA4, SRPK1, MAP2K6, MAPK11, NEB, MAZ, MKNK2, EEF2, DUSP9, ZFP36L1, ADRB2,
Protein Size: 360 - Molekulargewicht
- 41 kDa
- Gen-ID
- 1432
- NCBI Accession
- NM_001315, NP_001306
- UniProt
- Q16539
- Pathways
- MAPK Signalweg, Neurotrophin Signalübertragung, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Regulation of Muscle Cell Differentiation, Regulation of Cell Size, Hepatitis C, Toll-Like Receptors Cascades, Autophagie, Thromboxane A2 Receptor Signaling, BCR Signaling, S100 Proteine
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