MSH6 Antikörper (N-Term)

Produktnummer ABIN2776759

Produktdetails anti-MSH6 Antikörper

Target: MSH6 (MutS Homolog 6 (E. Coli) (MSH6))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Hund, Meerschweinchen, Rind (Kuh), Pferd, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MSH6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: ISDSESDIGG SDVEFKPDTK EEGSSDEISS GVGDSESEGL NSPVKVARKR

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 86%, Rabbit: 93%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against MSH6. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human MSH6

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 1360 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-MSH6 Antikörper (ABIN2776759)

Wedrén, Lovmar, Humphreys, Magnusson, Melhus, Syvänen, Kindmark, Landegren, Fermér, Stiger, Persson, Baron, Weiderpass: "Estrogen receptor alpha gene polymorphism and endometrial cancer risk--a case-control study." in: BMC cancer, Vol. 8, pp. 322, (2009) (PubMed).

Details zu MSH6

Target: MSH6 (MutS Homolog 6 (E. Coli) (MSH6))

Andere Bezeichnung: MSH6 (MSH6 Produkte)

Synonyme: GTBP antikoerper, GTMBP antikoerper, HNPCC5 antikoerper, HSAP antikoerper, p160 antikoerper, cb326 antikoerper, wu:fb36c12 antikoerper, LOC100227810 antikoerper, AU044881 antikoerper, AW550279 antikoerper, Gtmbp antikoerper, mutS homolog 6 antikoerper, mutS homolog 6 (E. coli) antikoerper, DNA mismatch repair protein antikoerper, MSH6 antikoerper, msh6 antikoerper, Msh6 antikoerper

Hintergrund: This gene encodes a protein similar to the MutS protein. In E. coli, the MutS protein helps in the recognition of mismatched nucleotides, prior to their repair. A highly conserved region of approximately 150 aa, called the Walker-A adenine nucleotide bind
Alias Symbols: GTBP, HNPCC5, HSAP
Protein Interaction Partner: BRCA1, UBC, SUMO2, PCNA, POLK, SAMHD1, GANAB, HYOU1, SUPT5H, XRCC6, ATP6V1B2, UBD, HDAC11, MSH2, CSNK2A1, SUPT16H, MSH3, MLH1, PMS2, RAD9A, RAD1, MUTYH, HUS1, SLX4, CUL3, NEDD8, FBXO25, SIRT7, XRCC5, PRKDC, BLM, TP53, RAD51, PMS1, SMARCAD1, CHAF1A, DTL, S
Protein Size: 1360

Molekulargewicht: 153 kDa

Gen-ID: 2956

NCBI Accession: NM_000179, NP_000170

UniProt: P52701

Pathways: DNA Reparatur, Chromatin Binding, Production of Molecular Mediator of Immune Response