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MSH6 Produkte

(MutS Homolog 6 (E. Coli) (MSH6))

Kategorien

This gene encodes a protein similar to the MutS protein. In E. coli, the MutS protein helps in the recognition of mismatched nucleotides, prior to their repair. A highly conserved region of approximately 150 aa, called the Walker-A adenine nucleotide binding motif, exists in MutS homologs. The encoded protein of this gene combines with MSH2 to form a mismatch recognition complex that functions as a bidirectional molecular switch that exchanges ADP and ATP as DNA mismatches are bound and dissociated. Mutations in this gene have been identified in individuals with hereditary nonpolyposis colon cancer (HNPCC) and endometrial cancer. [provided by RefSeq, Jul 2008].

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Ausgewählte MSH6 Kategorien

MSH6 Antikörper

High quality antibodies with extensive validation data.

MSH6 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene MSH6 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, IHC, ELISA, ICC, FACS
Validierungen
  • (1)
  • (7)
Kat. Nr. ABIN969293
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IHC, ELISA, ICC, FACS
Validierungen
  • (8)
Kat. Nr. ABIN7193706
Menge 0.1 mg
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IHC, ELISA, IF, Coat, FACS, StM
Validierungen
  • (7)
Kat. Nr. ABIN6939580
Menge 100 μg
Datenblatt Datenblatt

Empfohlene MSH6 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1311444
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Mouse
Source Tobacco (Nicotiana tabacum)
Validierungen
  • (1)
Kat. Nr. ABIN3134489
Menge 1 mg
Datenblatt Datenblatt
Reaktivität Human
Source Tobacco (Nicotiana tabacum)
Validierungen
  • (1)
Kat. Nr. ABIN3093948
Menge 1 mg
Datenblatt Datenblatt

Neueste Publikationen zu unseren MSH6 Produkten

Czink, Kloor, Goeppert, Fröhling, Uhrig, Weber, Meinel, Sutter, Weiss, Schirmacher, Doeberitz, Jäger, Springfeld: "Successful immune checkpoint blockade in a patient with advanced stage microsatellite-unstable biliary tract cancer." in: Cold Spring Harbor molecular case studies, Vol. 3, Issue 5, (2017) (PubMed).

Mohni, Mastrocola, Bai, Weller, Heinen: "DNA mismatch repair proteins are required for efficient herpes simplex virus 1 replication." in: Journal of virology, Vol. 85, Issue 23, pp. 12241-53, (2011) (PubMed).

Shahi, Lee, Kang, Lee, Hyun, Chang, Jun, You: "Mismatch-repair protein MSH6 is associated with Ku70 and regulates DNA double-strand break repair." in: Nucleic acids research, Vol. 39, Issue 6, pp. 2130-43, (2011) (PubMed).

Orthwein, Patenaude, Affar, Lamarre, Young, Di Noia: "Regulation of activation-induced deaminase stability and antibody gene diversification by Hsp90." in: The Journal of experimental medicine, Vol. 207, Issue 12, pp. 2751-65, (2010) (PubMed).

Valeri, Gasparini, Fabbri, Braconi, Veronese, Lovat, Adair, Vannini, Fanini, Bottoni, Costinean, Sandhu, Nuovo, Alder, Gafa, Calore, Ferracin, Lanza, Volinia, Negrini, McIlhatton, Amadori, Fishel et al.: "Modulation of mismatch repair and genomic stability by miR-155. ..." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 15, pp. 6982-7, (2010) (PubMed).

Wedrén, Lovmar, Humphreys, Magnusson, Melhus, Syvänen, Kindmark, Landegren, Fermér, Stiger, Persson, Baron, Weiderpass: "Estrogen receptor alpha gene polymorphism and endometrial cancer risk--a case-control study." in: BMC cancer, Vol. 8, pp. 322, (2009) (PubMed).

Becker, Creagh, ONeill: "Rab39a binds caspase-1 and is required for caspase-1-dependent interleukin-1beta secretion." in: The Journal of biological chemistry, Vol. 284, Issue 50, pp. 34531-7, (2009) (PubMed).

Grindedal, Møller, Eeles, Stormorken, Bowitz-Lothe, Landrø, Clark, Kvåle, Shanley, Maehle: "Germ-line mutations in mismatch repair genes associated with prostate cancer." in: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, Vol. 18, Issue 9, pp. 2460-7, (2009) (PubMed).

Masih, Kunnev, Melendy: "Mismatch Repair proteins are recruited to replicating DNA through interaction with Proliferating Cell Nuclear Antigen (PCNA)." in: Nucleic acids research, Vol. 36, Issue 1, pp. 67-75, (2008) (PubMed).

Cyr, Heinen: "Hereditary cancer-associated missense mutations in hMSH6 uncouple ATP hydrolysis from DNA mismatch binding." in: The Journal of biological chemistry, Vol. 283, Issue 46, pp. 31641-8, (2008) (PubMed).

Synonyme und alternative Namen zu MSH6

mutS homolog 6 (MSH6), mutS homolog 6 (E. coli) (msh6), mutS homolog 6 (msh6), mutS homolog 6 (Msh6), DNA mismatch repair protein (msh6), AU044881, AW550279, cb326, GTBP, GTMBP, Gtmbp, HNPCC5, HSAP, LOC100227810, p160, wu:fb36c12

Bezeichner auf Proteinebene für MSH6

  • DNA mismatch repair protein Msh6
  • G/T mismatch-binding protein
  • mutS-alpha 160 kDa subunit
  • sperm-associated protein
  • mutS homolog 6 (E. coli)
  • DNA mismatch repair protein Msh6-like
  • g/T mismatch-binding protein
  • p160
  • rCG61559-like
  • LOW QUALITY PROTEIN: DNA mismatch repair protein Msh6
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