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MSH6 Antikörper

MSH6 Reaktivität: Human, Maus, Affe IHC, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7255073
  • Target Alle MSH6 Antikörper anzeigen
    MSH6 (MutS Homolog 6 (E. Coli) (MSH6))
    Reaktivität
    • 79
    • 37
    • 30
    • 8
    • 5
    • 2
    • 1
    • 1
    • 1
    Human, Maus, Affe
    Wirt
    • 57
    • 19
    • 3
    Kaninchen
    Klonalität
    • 45
    • 34
    Polyklonal
    Konjugat
    • 47
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser MSH6 Antikörper ist unkonjugiert
    Applikation
    • 55
    • 26
    • 25
    • 21
    • 14
    • 13
    • 12
    • 8
    • 8
    • 7
    • 6
    • 6
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    Immunohistochemistry (IHC), Immunofluorescence (IF)
    Produktmerkmale
    Polyclonal Antibody
    Aufreinigung
    Affinity purification
    Immunogen
    Recombinant fusion protein of human MSH6 (NP_000170.1).
    Isotyp
    IgG
    Top Product
    Discover our top product MSH6 Primärantikörper
  • Applikationshinweise
    IHC 1:50-1:200 IF 1:20-1:100
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    MSH6 (MutS Homolog 6 (E. Coli) (MSH6))
    Andere Bezeichnung
    MSH6 (MSH6 Produkte)
    Synonyme
    GTBP antikoerper, GTMBP antikoerper, HNPCC5 antikoerper, HSAP antikoerper, p160 antikoerper, cb326 antikoerper, wu:fb36c12 antikoerper, LOC100227810 antikoerper, AU044881 antikoerper, AW550279 antikoerper, Gtmbp antikoerper, mutS homolog 6 antikoerper, mutS homolog 6 (E. coli) antikoerper, DNA mismatch repair protein antikoerper, MSH6 antikoerper, msh6 antikoerper, Msh6 antikoerper
    Hintergrund
    This gene encodes a member of the DNA mismatch repair MutS family. In E. coli, the MutS protein helps in the recognition of mismatched nucleotides prior to their repair. A highly conserved region of approximately 150 aa, called the Walker-A adenine nucleotide binding motif, exists in MutS homologs. The encoded protein heterodimerizes with MSH2 to form a mismatch recognition complex that functions as a bidirectional molecular switch that exchanges ADP and ATP as DNA mismatches are bound and dissociated. Mutations in this gene may be associated with hereditary nonpolyposis colon cancer, colorectal cancer, and endometrial cancer. Transcripts variants encoding different isoforms have been described.
    Gen-ID
    2956
    UniProt
    P52701
    Pathways
    DNA Reparatur, Chromatin Binding, Production of Molecular Mediator of Immune Response
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