p38 Antikörper (MAP kinase p38) (AA 151-200)

Details for Product anti-p38 Antibody No. ABIN1531504, Anbieter: Anmelden zum Anzeigen
Antigen
  • CSBP
  • CSBP1
  • CSBP2
  • CSPB1
  • EXIP
  • Mxi2
  • PRKM14
  • PRKM15
  • RK
  • SAPK2A
  • p38
  • p38ALPHA
  • mitogen-activated protein kinase 14
  • MAPK14
Epitop
AA 151-200, pThr179
68
57
31
15
15
10
10
6
5
5
4
4
3
3
2
2
2
2
1
1
1
1
1
1
1
1
1
1
Reaktivität
Human, Maus, Ratte (Rattus)
280
222
216
38
22
22
21
20
19
18
18
18
15
15
12
4
1
1
Wirt
Kaninchen
197
85
Klonalität
Polyklonal
Konjugat
Dieser p38 Antikörper ist unkonjugiert
7
7
7
7
6
5
3
3
3
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
Applikation
ELISA, Western Blotting (WB)
223
161
109
69
61
56
48
28
27
18
13
10
6
6
2
2
1
1
1
1
1
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Immunogen The antiserum was produced against synthesized peptide derived from human p38 MAPK around the phosphorylation site of Thr179 and Tyr181.
Isotyp IgG
Spezifität

p38 MAPK (Phospho-Thr179+Tyr181) Antibody detects endogenous levels of p38 MAPK only when phosphorylated at Thr179 and Tyr181.

PhosphorylationH:T179+Y181 M:T179+Y181 R:T179+Y181

Reinigung The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.
Reinheit > 95 %
Andere Bezeichnung p38 MAPK (p38 Antibody Abstract)
Hintergrund

Synonyms: protein, kinase p38-alpha, MAP kinase MXI2, MAP kinase p38, MAPK14, MAX-interacting protein 2, Mitogen-activated protein kinase 14, Mitogen-activated protein kinase p38, MK14, MXI2

NCBI Gene Symbol: MAPK14

Molekulargewicht 41 kDa
Gen-ID 1432
OMIM 600289
UniProt Q16539
Forschungsgebiet Kinases/Phosphatases
Pathways MAPK Signalweg, Neurotrophin Signalübertragung, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Regulation of Muscle Cell Differentiation, Hepatitis C, Toll-Like Receptors Cascades, Autophagie, Thromboxane A2 Receptor Signaling
Applikationshinweise WB: 1:500~1:1000 ELISA: 1:5000
Kommentare

Unigene-Number: Hs.485233, Hs.588289 (NCBI Gene Symbol: MAPK14)

Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 mg/mL
Buffer phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Stable at -20°C for at least 1 year.
Haltbarkeit 12 months
Bilder des Herstellers
Western Blotting (WB) image for anti-MAP kinase p38 (p38) (AA 151-200), (pThr179) antibody (ABIN1531504) Western blot analysis of extracts from A549 cells treated with etoposide 25uM 24hours...
Allgemeine Veröffentlichungen Lee, Laydon, McDonnell, Gallagher, Kumar, Green, McNulty, Blumenthal, Heys, Landvatter: "A protein kinase involved in the regulation of inflammatory cytokine biosynthesis." in: Nature, Vol. 372, Issue 6508, pp. 739-46, 1995 (PubMed).

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