anti-Senataxin (SETX) Antikörper

SETX encodes a protein named for its homology to the Sen1p protein of fungi which has RNA helicase activity encoded by a domain at the C-terminal end of the protein. Zusätzlich bieten wir Ihnen Senataxin Kits (2) und Senataxin Proteine (2) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
SETX 23064 Q7Z333
SETX 269254 A2AKX3
SETX 362096  
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Top anti-Senataxin Antikörper auf antikoerper-online.de

Showing 10 out of 114 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert IP, WB Western Blot and Immunoprecipitation: Senataxin Antibody [ABIN252880] - Detection of Human Senataxin by Western Blot and Immunoprecipitation. Samples: Whole cell lysate (15 and 50 mcg for WB, 1 mg for IP, 20% of IP loaded) from HeLa cells. Antibodies: Affinity purified rabbit anti-Senataxin antibody ABIN252880 used for WB at 0.1 mcg/ml (A) and 1 mcg/ml (B) and used for IP at 3 mcg/mg lysate. Senataxin was also immunoprecipitated by rabbit anti-Senataxin antibody ABIN252881, which recognizes a downstream epitope. Detection: Chemiluminescence with exposure times of 3 minutes (A) and 30 seconds (B). Immunoprecipitation: Senataxin Antibody [ABIN2528802] - Samples: Whole cell lysate (0.5 or 1.0 mg per IP reaction; 20% of IP loaded) from HeLa cells prepared using NETN lysis buffer. Antibodies: Affinity purified rabbit anti-Senataxin antibody used for IP at 6 ug per reaction. Senataxin was also immunoprecipitated by a previous lot of this antibody and rabbit anti-Senataxin antibody. For blotting immunoprecipitated Senataxin, the antibody was used at 1 ug/ml. Detection: Chemiluminescence with an exposure time of 3 minutes. 100 μL Anmelden zum Anzeigen 2 bis 4 Tage
371,00 €
Details
Human Kaninchen Unkonjugiert ChIP, IP, WB Western Blot and Immunoprecipitation: Senataxin Antibody [ABIN252881] - Detection of Human Senataxin by Western Blot and Immunoprecipitation. Samples: Whole cell lysate (15 and 50 mcg for WB, 1 mg for IP, 20% of IP loaded) from HeLa cells. Antibodies: Affinity purified rabbit anti-Senataxin antibody ABIN252881 used for WB at 0.4 mcg/ml (A) and 1 mcg/ml (B) and used for IP at 3 mcg/mg lysate. Senataxin was also immunoprecipitated by rabbit anti-Senataxin antibody ABIN252880, which recognizes an upstream epitope. Detection: Chemiluminescence with exposure times of 3 minutes (A) and 30 seconds (B). Western Blot: Senataxin Antibody  - Detection of Human Senataxin by Western Blot. Samples: Whole cell lysate (15 and 50 ug) from HeLa cells prepared using NETN lysis buffer. Antibody: Affinity purified rabbit anti-Senataxin antibody  used for WB at 0.04 ug/ml. Detection: Chemiluminescence with an exposure time of 3 minutes. 100 μL Anmelden zum Anzeigen 2 bis 4 Tage
371,00 €
Details
Human Kaninchen Unkonjugiert ICC, IF, IHC, IHC (p), IP, WB Immunohistochemistry-Paraffin: Senataxin Antibody [NBP1-94712] - IHC analysis of a formalin fixed paraffin embedded tissue section of human heart (verticle section) using 1:200 dilution of lot A2 of Senataxin antibody. The antibody generated a very strong staining in the cytoplasm and the nuclei of the muscle cells. No signal was found in the perimysium & endomycium (connective tissue) of the section. Immunohistochemistry-Paraffin: Senataxin Antibody [NBP1-94712] - IHC analysis of a formalin fixed paraffin embedded tissue section of human heart (transverse section) using 1:200 dilution of lot A2 of Senataxin antibody. The antibody generated a very strong staining in the cytoplasm and the nuclei of the muscle cells. No signal was found in the perimysium & endomycium area (connective tissue) of the section. 0.1 mL Anmelden zum Anzeigen 2 bis 4 Tage
311,00 €
Details
Human Kaninchen Unkonjugiert IF (p), IHC (p), WB Formalin-fixed and paraffin embedded muscle of mouse embryo labeled with Anti-Senataxin/SETX Polyclonal Antibody, Unconjugated (ABIN1385872) at 1:200, followed by conjugation to the secondary antibody and DAB staining 100 μL Anmelden zum Anzeigen 9 bis 12 Tage
304,36 €
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Human Maus Unkonjugiert IF Immunofluorescence of monoclonal antibody to SETX on HeLa cell  (antibody concentration 10 µg/mL). 0.1 mg Anmelden zum Anzeigen 12 bis 16 Tage
454,76 €
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Human Kaninchen Alexa Fluor 594 IF (p)   100 μL Anmelden zum Anzeigen 18 bis 22 Tage
414,64 €
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Human Maus Unkonjugiert IF 0.1 mg Anmelden zum Anzeigen 4 bis 5 Tage
601,76 €
Details
Human Maus Unkonjugiert FACS, IHC, IHC (p) Immunohistochemistry-Paraffin: Senataxin Antibody (4G1) [NBP2-52726] - Senataxin antibody clone 4G1 was tested on human prostate tissue sections and generated strong cytoplasmic-nuclear staining in the secretary/basal epithelial cells as well as the dense connective tissue. Flow (Intracellular): Senataxin Antibody (4G1) [NBP2-52726] - An intracellular stain was performed on HepG2 cells with Senataxin Antibody (4G1) antibody NBP2-52726 (blue) and a matched isotype control NBP2-27231 (orange). Cells were fixed with 4% PFA and then permeablized with 0.1% saponin. Cells were incubated in an antibody dilution of 5 ug/mL for 30 minutes at room temperature, followed by mouse F(ab)2 IgG (H+L) APC-conjugated secondary antibody (F0101B, R&D Systems). 0.1 mg Anmelden zum Anzeigen 2 bis 4 Tage
291,00 €
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Human Kaninchen Cy3 IF (p)   100 μL Anmelden zum Anzeigen 18 bis 22 Tage
414,64 €
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Human Kaninchen HRP IHC (p), WB   100 μL Anmelden zum Anzeigen 18 bis 22 Tage
414,64 €
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SETX Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

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Am meisten referenzierte anti-Senataxin Antikörper

  1. Human Polyclonal SETX Primary Antibody für IP, WB - ABIN252880 : Richard, Feng, Manley: A SUMO-dependent interaction between Senataxin and the exosome, disrupted in the neurodegenerative disease AOA2, targets the exosome to sites of transcription-induced DNA damage. in Genes & development 2013 (PubMed)
    Show all 2 Pubmed References

  2. Human Polyclonal SETX Primary Antibody für ICC, IF - ABIN4352660 : Choudhury, Vs, Mushtaq, Kumar: Altered translational repression of an RNA-binding protein, Elav by AOA2-causative Senataxin mutation. in Synapse (New York, N.Y.) 2017 (PubMed)
    Show all 2 Pubmed References

  3. Human Polyclonal SETX Primary Antibody für ChIP, IP - ABIN252881 : Zhao, Gish, Braunschweig, Li, Ni, Schmitges, Zhong, Liu, Li, Moffat, Vedadi, Min, Pawson, Blencowe, Greenblatt: SMN and symmetric arginine dimethylation of RNA polymerase II C-terminal domain control termination. in Nature 2016 (PubMed)

Weitere Antikörper gegen Senataxin Interaktionspartner

Human Senataxin (SETX) Interaktionspartner

  1. The pan (zeige SUPT6H Antikörper)-neuronal expression of wild-type or mutant forms of human senataxin induced morphological plasticity at neuromuscular junction synapses.

  2. Novel compound heterozygous mutations of SETX in Chinese AOA2 pedigree were identified, which broaden the mutation spectrum of SETX.

  3. The role of senataxin in regulating gene expression on a genome-wide scale in Ataxia oculomotor apraxia 2 neurons is described.

  4. these data indicate a potentially causal link among inborn errors in SETX, susceptibility to infection and the development of neurologic disorders.

  5. AOA2 with myoclonus associated with mutations in SETX and AFG3L2 (zeige AFG3L2 Antikörper)

  6. BRCA1/SETX complexes support a DNA repair mechanism that addresses R-loop-based DNA damage at transcriptional pause sites.

  7. Results identify novel genes related to senataxin function in normal and disease states.

  8. genetic variations in the senataxin gene may contribute to Alzheimer's disease pathogenesis in the Taiwanese Han population.

  9. Protein interaction analysis of senataxin and the ALS4 L389S mutant yields insights into senataxin post-translational modification and uncovers mutant-specific binding with a brain cytoplasmic RNA-encoded peptide.

  10. Description of a new SETX gene mutation, which when combined with a recognized SETX mutation results in ataxia with oculomotor apraxia type 2.

Mouse (Murine) Senataxin (SETX) Interaktionspartner

  1. Results identify novel genes related to senataxin function in normal and disease states.

  2. These data support key roles for senataxin in coordinating meiotic crossing-over with transcription and in gene silencing to protect the integrity of the genome.

Senataxin (SETX) Antigen-Profil

Protein Überblick

This gene encodes a protein named for its homology to the Sen1p protein of fungi which has RNA helicase activity encoded by a domain at the C-terminal end of the protein. The protein encoded by this gene contains a DNA/RNA helicase domain at its C-terminal end which suggests that it may be involved in both DNA and RNA processing. Mutations in this gene have been associated with ataxia-ocular apraxia-2 (AOA2) and an autosomal dominant form of juvenile amyotrophic lateral sclerosis (ALS4).

Genbezeichner und Symbole assoziert mit anti-Senataxin (SETX) Antikörper

  • senataxin (SETX) Antikörper
  • senataxin (setx) Antikörper
  • senataxin (Setx) Antikörper
  • A130090N03 Antikörper
  • A930037J23Rik Antikörper
  • Als4 Antikörper
  • AOA2 Antikörper
  • AW060766 Antikörper
  • bA479K20.2 Antikörper
  • mKIAA0625 Antikörper
  • RGD1565575 Antikörper
  • SCAR1 Antikörper
  • Sen1 Antikörper
  • SETX Antikörper
  • wu:fj92h09 Antikörper

Bezeichner auf Proteinebene für anti-Senataxin (SETX) Antikörper

senataxin , amyotrophic lateral sclerosis 4 , probable helicase senataxin-like , SEN1 homolog , amyotrophic lateral sclerosis 4 protein , probable helicase senataxin , amyotrophic lateral sclerosis 4 homolog , amyotrophic lateral sclerosis 4 protein homolog , DEAxQ-box helicase , tRNA splicing endonuclease regulator 1

GENE ID SPEZIES
100066679 Equus caballus
417170 Gallus gallus
464815 Pan troglodytes
562474 Danio rerio
100090737 Ornithorhynchus anatinus
100145435 Xenopus (Silurana) tropicalis
100405920 Callithrix jacchus
100445729 Pongo abelii
100468613 Ailuropoda melanoleuca
100542448 Meleagris gallopavo
23064 Homo sapiens
269254 Mus musculus
362096 Rattus norvegicus
480691 Canis lupus familiaris
534284 Bos taurus
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