Senataxin Produkte
(Senataxin (SETX))
Kategorien
This gene encodes a protein named for its homology to the Sen1p protein of fungi which has RNA helicase activity encoded by a domain at the C-terminal end of the protein. The protein encoded by this gene contains a DNA/RNA helicase domain at its C-terminal end which suggests that it may be involved in both DNA and RNA processing. Mutations in this gene have been associated with ataxia-ocular apraxia-2 (AOA2) and an autosomal dominant form of juvenile amyotrophic lateral sclerosis (ALS4). [provided by RefSeq, Jul 2008].
antibodies-online.com steht für hochwertige Forschungsprodukte. Suchen, finden und bestellen Sie Tools mit umfangreichen Validierungsdaten, Bildern, Referenzen. Unser wissenschaftlicher Kundenservice steht Ihnen jederzeit zur Verfügung, wenn Sie Fragen zur Auswahl oder Anwendung unserer Produkte haben.
Ausgewählte Senataxin Kategorien
Senataxin Antikörper
High quality antibodies with extensive validation data.
Senataxin ELISA Kits
Reliable ELISA kits for a wide range of species.
Empfohlene Senataxin Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IF
Validierungen
- (5)
Kat. Nr.
ABIN565001
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
ELISA, IHC
Validierungen
- (1)
Kat. Nr.
ABIN7164533
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Mouse
Applikation
WB, ELISA, IF (cc), IF (p), IHC (fro), IHC (p), ICC
Validierungen
- (1)
Kat. Nr.
ABIN1385872
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene Senataxin ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Validierungen
Kat. Nr.
ABIN1149655
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Mouse
Analytical Method
Validierungen
Kat. Nr.
ABIN1149656
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene Senataxin Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1319693
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
HEK-293T Cells
Validierungen
- (1)
Kat. Nr.
ABIN2731631
Menge
20 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren Senataxin Produkten
: "Sae2/CtIP prevents R-loop accumulation in eukaryotic cells." in: eLife, Vol. 7, (2019) (PubMed).: "Dual Processing of R-Loops and Topoisomerase I Induces Transcription-Dependent DNA Double-Strand Breaks." in: Cell reports, Vol. 28, Issue 12, pp. 3167-3181.e6, (2019) (PubMed).
: "Senataxin resolves RNA:DNA hybrids forming at DNA double-strand breaks to prevent translocations." in: Nature communications, Vol. 9, Issue 1, pp. 533, (2018) (PubMed).
: "A senataxin-associated exonuclease SAN1 is required for resistance to DNA interstrand cross-links." in: Nature communications, Vol. 9, Issue 1, pp. 2592, (2018) (PubMed).
: "Altered translational repression of an RNA-binding protein, Elav by AOA2-causative Senataxin mutation." in: Synapse (New York, N.Y.), Vol. 71, Issue 5, (2017) (PubMed).
: "Functions of Replication Protein A as a Sensor of R Loops and a Regulator of RNaseH1." in: Molecular cell, Vol. 65, Issue 5, pp. 832-847.e4, (2017) (PubMed).
: "SMN and symmetric arginine dimethylation of RNA polymerase II C-terminal domain control termination." in: Nature, Vol. 529, Issue 7584, pp. 48-53, (2016) (PubMed).
: "A SUMO-dependent interaction between Senataxin and the exosome, disrupted in the neurodegenerative disease AOA2, targets the exosome to sites of transcription-induced DNA damage." in: Genes & development, Vol. 27, Issue 20, pp. 2227-32, (2013) (PubMed).
Synonyme und alternative Namen zu Senataxin
senataxin (SETX), senataxin (setx), senataxin (Setx), A130090N03, A930037J23Rik, ALS4, Als4, AOA2, AW060766, bA479K20.2, mKIAA0625, RGD1565575, SCAR1, Sen1, SETX, wu:fj92h09Bezeichner auf Proteinebene für Senataxin
- senataxin
- amyotrophic lateral sclerosis 4
- probable helicase senataxin-like
- SEN1 homolog
- amyotrophic lateral sclerosis 4 protein
- probable helicase senataxin
- amyotrophic lateral sclerosis 4 homolog
- amyotrophic lateral sclerosis 4 protein homolog
- DEAxQ-box helicase
- tRNA splicing endonuclease regulator 1
Sie sind hier:
