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Separase Produkte

(Extra Spindle Poles Like 1 (ESPL1))

Kategorien

Stable cohesion between sister chromatids before anaphase and their timely separation during anaphase are critical for chromosome inheritance.

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Ausgewählte Separase Kategorien

Separase Antikörper

High quality antibodies with extensive validation data.

Separase ELISA Kits

Reliable ELISA kits for a wide range of species.

Empfohlene Separase Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
ReaktivitätHuman
ApplikationIHC (p), ELISA, WB
Validierungen
  • (7)
  • collections(3)
Kat. Nr.ABIN564183
Menge100 μg
ReaktivitätHuman, Mouse
ApplikationIF, IHC, ELISA, WB
Validierungen
  • collections(3)
Kat. Nr.ABIN1532260
Menge100 μg
ReaktivitätHuman
ApplikationDB, IHC (p)
Validierungen
  • (1)
  • collections(2)
Kat. Nr.ABIN389654
Menge400 μL

Empfohlene Separase ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
ReaktivitätHuman, Mouse
Analytical MethodQualitative Cell ELISA
Validierungen
Kat. Nr.ABIN1380135
Menge2 x 96 tests
ReaktivitätHuman
Analytical MethodQuantitative Sandwich ELISA
Validierungen
Kat. Nr.ABIN5592033
Menge96 tests
ReaktivitätHuman, Mouse
Analytical MethodQualitative Cell ELISA
Validierungen
Kat. Nr.ABIN2684167
Menge1 kit

Empfohlene Separase Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
ReaktivitätMouse
SourceEscherichia coli (E. coli)
Validierungen
  • collections(1)
Kat. Nr.ABIN3121753
Menge1 mg
ReaktivitätHuman
SourceWheat germ
Validierungen
  • collections(1)
Kat. Nr.ABIN1353121
Menge10 μg

Neueste Publikationen zu unseren Separase Produkten

Mukherjee, Ge, Zhang, Edwards, Sumazin, Sharan, Rao, Medina, Pati: "MMTV-Espl1 transgenic mice develop aneuploid, estrogen receptor alpha (ER?)-positive mammary adenocarcinomas." in: Oncogene, Vol. 33, Issue 48, pp. 5511-22, 2014 (PubMed).

Mukherjee, Byrd, Brawley, Bielamowicz, Li, Merchant, Maitra, Sumazin, Fuller, Kew, Sun, Powell, Ahmed, Zhang, Pati: "Overexpression and constitutive nuclear localization of cohesin protease Separase protein correlates with high incidence of relapse and reduced overall survival in glioblastoma multiforme." in: Journal of neuro-oncology, Vol. 119, Issue 1, pp. 27-35, 2014 (PubMed).

Zhang, Scorsone, Ge, Kaffes, Dobrolecki, Mukherjee, Lewis, Berg, Stephan, Pati: "Identification and Characterization of Separase Inhibitors (Sepins) for Cancer Therapy." in: Journal of biomolecular screening, Vol. 19, Issue 6, pp. 878-889, 2014 (PubMed).

Haaß, Stehle, Nittka, Giehl, Schrotz-King, Fabarius, Hofmann, Seifarth: "The proteolytic activity of separase in BCR-ABL-positive cells is increased by imatinib." in: PLoS ONE, Vol. 7, Issue 8, pp. e42863, 2012 (PubMed). Von den Autoren verwendete Methode: Western Blotting (WB)

Mukherjee, Ge, Zhang, Huang, Nakamura, Minor, Fofanov, Rao, Herron, Pati: "Separase loss of function cooperates with the loss of p53 in the initiation and progression of T- and B-cell lymphoma, leukemia and aneuploidy in mice." in: PLoS ONE, Vol. 6, Issue 7, pp. e22167, 2011 (PubMed).

Panigrahi, Zhang, Mao, Pati: "Calpain-1 cleaves Rad21 to promote sister chromatid separation." in: Molecular and cellular biology, Vol. 31, Issue 21, pp. 4335-47, 2011 (PubMed).

Meyer, Fofanov, Panigrahi, Merchant, Zhang, Pati: "Overexpression and mislocalization of the chromosomal segregation protein separase in multiple human cancers." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 15, Issue 8, pp. 2703-10, 2009 (PubMed).

Kim, Jeon, Ha, Park, Kim, Shin, Lee, Chung, Lee: "Functional interaction between BubR1 and securin in an anaphase-promoting complex/cyclosomeCdc20-independent manner." in: Cancer research, Vol. 69, Issue 1, pp. 27-36, 2009 (PubMed).

Sun, Kucej, Fan, Yu, Sun, Zou: "Separase is recruited to mitotic chromosomes to dissolve sister chromatid cohesion in a DNA-dependent manner." in: Cell, Vol. 137, Issue 1, pp. 123-32, 2009 (PubMed). (Probematerial (Species): Human).

Fujita, Epperly, Zou, Greenberger, Wan: "Regulation of the anaphase-promoting complex-separase cascade by transforming growth factor-beta modulates mitotic progression in bone marrow stromal cells." in: Molecular biology of the cell, Vol. 19, Issue 12, pp. 5446-55, 2008 (PubMed).

Synonyme und alternative Namen zu Separase

extra spindle pole bodies like 1, separase (ESPL1), extra spindle poles like 1 (espl1), extra spindle pole bodies 1, separase (Espl1), extra spindle pole bodies like 1, separase (Espl1), AL024103, AU045071, Cerp, ESP1, mp:zf637-3-001691, PRCE, SEPA, SSE

Gen-IDs für verschiedene Spezies

GENE ID SPEZIES
9700 Homo sapiens
337864 Danio rerio
506740 Bos taurus
105988 Mus musculus
315330 Rattus norvegicus
425536 Gallus gallus
607879 Canis lupus familiaris
100063779 Equus caballus

Bezeichner auf Proteinebene für Separase

  • caspase-like protein ESPL1
  • extra spindle poles like 1
  • extra spindle poles-like 1 protein
  • separin
  • separin, cysteine protease
  • cds
  • separase
  • cease&desist
  • zf637-3-001691
  • Cut1/ESP1 related protein
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