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Human WNT9A Protein expressed in Wheat germ - ABIN1325373
Kulawig, Krüger, Klein, Konthur, Schütte, Klose, Kaps, Endres: Identification of fibronectin as a major factor in human serum to recruit subchondral mesenchymal progenitor cells. in The international journal of biochemistry & cell biology 2013
Wnt9a input is required prior to aorta formation.
the chaperon Wls (zeige WLS Proteine) and its ligands Wnt9a and Wnt5b (zeige WNT5B Proteine) are expressed in the ectoderm, whereas juxtaposed chondrocytes express Frzb (zeige FRZB Proteine) and Gpc4 (zeige GPC4 Proteine).
disruption of wls (zeige WLS Proteine) resulted in a significant loss of craniofacial bone, whereas lack of gpc4 (zeige GPC4 Proteine), wnt5b (zeige WNT5B Proteine) and wnt9a resulted in severely delayed endochondral ossification.
These data corroborate the central role for Wnt (zeige WNT2 Proteine) signaling in vertebrate craniofacial development.
Wnt9a is expressed in the embryonic pancreas and that its deficiency enhances activation of the endocrine transcriptional program and increases the number of endocrine cells at birth.
These studies reveal how carrageenan exposure can lead to transcriptional events in colonic epithelial cells through decline in arylsulfatase B (zeige ARSB Proteine) activity, with subsequent impact on C4S (zeige CHST11 Proteine), galectin-3 (zeige LGALS3 Proteine), Sp1 (zeige SP1 Proteine), and Wnt9A
The mRNA levels of Wnt3 (zeige WNT3 Proteine), 6, and 9a were significantly upregulated in the intestinal epithelial cells by Salmonella.
Embryos double-heterozygous for Wnt9a and beta-catenin (zeige CTNNB1 Proteine) show reduced Ihh (zeige IHH Proteine) expression.
This manipulation increased one type of sensory hair cell (tall HCs (zeige HLCS Proteine)) at the expense of another (short HCs (zeige HLCS Proteine)) that is usually located furthest from the Wnt9a source. The extraneous tall HCs (zeige HLCS Proteine) that replaced short HCs (zeige HLCS Proteine) showed some physiological properties and neuronal connections consistent with a fate switch.
Inhibition of WNT (zeige WNT2 Proteine) signaling by the PORCN (zeige PORCN Proteine) inhibitor WNT974 reduced metastatic spread of UM-SCC (zeige CYP11A1 Proteine) cells, especially in UM-SCCs with Notch1 (zeige NOTCH1 Proteine) deficiency.
Silencing Wnt9A increased the expression of CHST11 (zeige CHST11 Proteine) in the colonic epithelial cells, and chromatin immunoprecipitation assay demonstrated enhancing effects of Wnt9A siRNA and exogenous BMP4 (zeige BMP4 Proteine) on the CHST11 (zeige CHST11 Proteine) promoter
These studies reveal how carrageenan exposure can lead to transcriptional events in colonic epithelial cells through decline in arylsulfatase B (zeige ARSB Proteine) activity, with subsequent impact on C4S (zeige CHST11 Proteine), galectin-3 (zeige LGALS3 Proteine), Sp1 (zeige PSG1 Proteine), and Wnt9A
Transgenic wnt9a is required for palatal extension wherein the chondrocytes form a proliferative front, undergo morphological change and intercalate to form the ethmoid plate.
Using DirectDNA sequencing analysis, we detected ATBF1, CYLD (zeige CYLD Proteine), PARK2 (zeige PARK2 Proteine) and WNT9A mutations in stomach and colorectal cancers
Results demonstrated significant up-regulation of WNT-3 (zeige WNT3 Proteine), WNT-4 (zeige WNT4 Proteine), WNT-5B (zeige WNT5B Proteine), WNT-7B (zeige WNT7B Proteine), WNT-9A, WNT-10A (zeige WNT10A Proteine), and WNT (zeige WNT2 Proteine)-16B in patients with CLL compared to normal subjects.
Found clustered with WNT3A (zeige WNT3A Proteine) on 1q42. .
5'-flanking promoter region was significantly divergent between human WNT9A and rodent Wnt9a genes.
These results suggests the expression level of human Wnt9a in MCF-7 that breast cancer may play a role in adjusting the rate of cellular proliferation.
The WNT gene family consists of structurally related genes that encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It is expressed in gastric cancer cell lines. The protein encoded by this gene shows 75% amino acid identity to chicken Wnt14, which has been shown to play a central role in initiating synovial joint formation in the chick limb. This gene is clustered with another family member, WNT3A, in the chromosome 1q42 region.
wingless-type MMTV integration site family, member 9A
, protein Wnt-9a
, protein Wnt-9a-like
, wingless-type MMTV integration site 14
, wingless-type MMTV integration site family, member 14
, wingless related MMTV integration site 9A
, wingless-type MMTV integration site 9A