anti-Kaninchen DAAM1 Antikörper für Western Blotting

Recommended DAAM1 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Dishevelled Associated Activator of Morphogenesis 1 (DAAM1) Antikörper
  • daam-1
  • xdaam1
  • DAAM1
  • DKFZp468D0524
  • 1700066F09Rik
  • 2310028E21Rik
  • AI503486
  • E130308H01
  • mKIAA0666
  • daam1
  • dishevelled associated activator of morphogenesis 1 S homeolog
  • dishevelled associated activator of morphogenesis 1
  • dishevelled associated activator of morphogenesis 1a
  • daam1.S
  • daam1
  • DAAM1
  • Daam1
  • daam1a
Epitop
Middle Region
29
12
8
4
3
3
3
3
2
1
1
1
1
1
Reaktivität
Rind (Kuh), Hund, Meerschweinchen, Pferd, Human, Maus, Kaninchen, Ratte (Rattus), Zebrafisch (Danio rerio)
76
14
14
9
4
4
3
1
1
1
1
1
1
Wirt
Kaninchen
70
6
Klonalität
Polyklonal
Konjugat
Dieser DAAM1 Antikörper ist unkonjugiert
5
5
5
5
5
5
Applikation
Western Blotting (WB)
72
48
46
11
9
6
4
2
1
1
1
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Bilder

Produktnummer ABIN2786070
$ 289.00
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
1 ABIN463923 WB Rabbit IgG AA 396-445 Anmelden zum Anzeigen Polyclonal 0

General

Antigen Dishevelled Associated Activator of Morphogenesis 1 (DAAM1) Antikörper
Epitop Middle Region
(29), (12), (8), (4), (3), (3), (3), (3), (2), (1), (1), (1), (1), (1)
Reaktivität Rind (Kuh), Hund, Meerschweinchen, Pferd, Human, Maus, Kaninchen, Ratte (Rattus), Zebrafisch (Danio rerio)
(76), (14), (14), (9), (4), (4), (3), (1), (1), (1), (1), (1), (1)
Wirt Kaninchen
(70), (6)
Klonalität
Polyklonal
Konjugat Dieser DAAM1 Antikörper ist unkonjugiert
(5), (5), (5), (5), (5), (5)
Applikation Western Blotting (WB)
(72), (48), (46), (11), (9), (6), (4), (2), (1), (1), (1)
Pubmed 1 Publikation vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-DAAM1 Antikörper

Target Details DAAM1 Anwendungsinformationen Handhabung Referenzen für anti-DAAM1 Antikörper (ABIN2786070) Bilder
Blocking Peptide Zu diesem Produkt passt das Blocking Peptide ABIN975574.
Sequenz GNTVQYWLLL DRIIQQIVIQ NDKGQDPDST PLENFNIKNV VRMLVNENEV
Homologie Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%
Produktmerkmale This is a rabbit polyclonal antibody against DAAM1. It was validated on Western Blot using a cell lysate as a positive control.
Reinigung Affinity Purified
Immunogen The immunogen is a synthetic peptide directed towards the middle region of human DAAM1

Target Details DAAM1

Produktdetails anti-DAAM1 Antikörper Anwendungsinformationen Handhabung Referenzen für anti-DAAM1 Antikörper (ABIN2786070) Bilder zurück nach oben
Antigen
Andere Bezeichnung DAAM1 (DAAM1 Antibody Abstract)
Hintergrund Functions of the cell cortex, including motility, adhesion, and cytokinesis, are mediated by the reorganization of the actin cytoskeleton and recent evidence suggests a role for the Formin homology (FH) proteins in these processes. The protein encoded by this gene contains FH domains and belongs to a novel FH protein subfamily implicated in cell polarity. Wnt/Fz signaling activates the small GTPase Rho, a key regulator of cytoskeleton architecture, to control cell polarity and movement during development. Activation requires Dvl-Rho complex formation, an assembly mediated by this gene product, which is thought to function as a scaffolding protein.Functions of the cell cortex, including motility, adhesion, and cytokinesis, are mediated by the reorganization of the actin cytoskeleton and recent evidence suggests a role for the Formin homology (FH) proteins in these processes. The protein encoded by this gene contains FH domains and belongs to a novel FH protein subfamily implicated in cell polarity. Wnt/Fz signaling activates the small GTPase Rho, a key regulator of cytoskeleton architecture, to control cell polarity and movement during development. Activation requires Dvl-Rho complex formation, an assembly mediated by this gene product, which is thought to function as a scaffolding protein. Evidence of alternative splicing has been observed for this gene but the full-length nature of these variants has not been determined.
Alias Symbols: FLJ41657, KIAA0666
Protein Interaction Partner: UBC, PRPF40A, B3GALT4, AMBP, MAP3K7, DVL2, DVL1, RHOA,
Protein Size: 1078
Molekulargewicht 123 kDa
Gen-ID 23002
NCBI Accession NM_014992, NP_055807
UniProt Q9Y4D1
Pathways WNT Signalweg

Anwendungsinformationen

Produktdetails anti-DAAM1 Antikörper Target Details DAAM1 Handhabung Referenzen für anti-DAAM1 Antikörper (ABIN2786070) Bilder zurück nach oben
Applikationshinweise Optimal working dilutions should be determined experimentally by the investigator.
Kommentare

Antigen size: 1078 AA

Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-DAAM1 Antikörper Target Details DAAM1 Anwendungsinformationen Referenzen für anti-DAAM1 Antikörper (ABIN2786070) Bilder zurück nach oben
Format Liquid
Konzentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freeze-thaw cycles.
Lagerung -20 °C
Informationen zur Lagerung For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-DAAM1 Antikörper (ABIN2786070)

Produktdetails anti-DAAM1 Antikörper Target Details DAAM1 Anwendungsinformationen Handhabung Bilder zurück nach oben
Allgemeine Veröffentlichungen

Higashi, Ikeda, Shirakawa, Kondo, Kawato, Horiguchi, Okuda, Okawa, Fukai, Nureki, Kita, Horiuchi: "Biochemical characterization of the Rho GTPase-regulated actin assembly by diaphanous-related formins, mDia1 and Daam1, in platelets." in: The Journal of biological chemistry, Vol. 283, Issue 13, pp. 8746-55, 2008

Bilder

Produktdetails anti-DAAM1 Antikörper Target Details DAAM1 Anwendungsinformationen Handhabung Referenzen für anti-DAAM1 Antikörper (ABIN2786070) zurück nach oben
Bilder des Herstellers
Western Blotting (WB) image for anti-Dishevelled Associated Activator of Morphogenesis 1 (DAAM1) (Middle Region) antibody (ABIN2786070) WB Suggested Anti-DAAM1 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: