anti-Schwein p65 Antikörper für Immunohistochemistry

Recommended p65 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Nuclear Factor-KB P65 (NFkBP65) Antikörper
  • C-Rel
  • NFKB3
  • p65
  • NFkB
  • c-rel
  • zgc:100833
  • REL proto-oncogene, NF-kB subunit
  • RELA proto-oncogene, NF-kB subunit
  • v-rel reticuloendotheliosis viral oncogene homolog A (avian)
  • v-rel avian reticuloendotheliosis viral oncogene homolog
  • REL
  • RELA
  • Rela
  • Rel
  • rel
Epitop
Middle Region
120
77
73
63
50
48
43
40
38
38
29
29
25
16
16
16
15
15
14
13
13
13
10
10
10
8
8
8
7
6
6
6
6
6
5
5
5
4
4
4
4
4
4
4
4
4
4
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reaktivität
Rind (Kuh), Hund, Human, Maus, Schwein, Ratte (Rattus)
1213
737
567
70
67
52
30
24
19
16
12
8
6
5
4
1
1
1
Wirt
Kaninchen
1073
137
17
10
1
Klonalität
Polyklonal
Konjugat
Dieser p65 Antikörper ist unkonjugiert
30
29
23
19
18
17
17
12
12
12
11
8
8
8
8
8
8
8
8
4
4
3
3
3
2
2
2
2
2
2
1
1
1
Applikation
Immunohistochemistry (IHC), Western Blotting (WB)
930
552
391
281
213
187
105
101
85
37
29
20
17
12
12
6
6
6
5
5
4
2
1
1
Optionen
Hersteller
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Bilder

Produktnummer ABIN2779331
$ 289.00
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
9.314878 ABIN2706683 ChIP IC IF IHC WB Rabbit acLys310 Anmelden zum Anzeigen Polyclonal 0
9.314878 ABIN2706678 IP IHC WB Rabbit pSer254 Anmelden zum Anzeigen Polyclonal 0
9.314878 ABIN2706682 IC IF IHC WB Rabbit Center Anmelden zum Anzeigen Polyclonal 0
9.314878 ABIN2706679 IP IHC WB Rabbit pSer276 Anmelden zum Anzeigen Polyclonal 0
9.314878 ABIN2706681 IP IHC WB Rabbit Center Anmelden zum Anzeigen Polyclonal 0
9.314878 ABIN2705047 IP IHC WB Rabbit C-Term Anmelden zum Anzeigen Polyclonal 0
9.314878 ABIN2705044 IP IHC WB Rabbit C-Term, pSer468 Anmelden zum Anzeigen Polyclonal 0
9.314878 ABIN2705045 IP IHC WB Rabbit C-Term, pSer536 Anmelden zum Anzeigen Polyclonal 0
9.314878 ABIN2705052 IP IHC WB Rabbit C-Term Anmelden zum Anzeigen Polyclonal 0
9.314878 ABIN2706680 IC IF IHC WB Rabbit pSer311 Anmelden zum Anzeigen Polyclonal 0
9.314878 ABIN2470321 IP IHC ELISA WB Rabbit AA 2440-2457 Anmelden zum Anzeigen Polyclonal 0
1 ABIN2755706 IHC WB Rabbit Center Anmelden zum Anzeigen Polyclonal 0
1 ABIN218582 ELISA IHC IHC (p) IP WB Rabbit pSer529 Anmelden zum Anzeigen Polyclonal 0
1 ABIN2627581 IHC IHC (p) WB Rabbit C-Term Anmelden zum Anzeigen Polyclonal 0
1 ABIN2627580 ICC IHC IHC (p) WB Rabbit IgG AA 143-158 Anmelden zum Anzeigen Polyclonal 0
1 ABIN2578783 ChIP ICC IF IHC IHC (p) WB Rabbit acLys310 Anmelden zum Anzeigen Polyclonal 0
1 ABIN2744016 IHC IHC (p) IP WB Rabbit pThr254 Anmelden zum Anzeigen Polyclonal 0
1 ABIN2578773 IHC IHC (p) IP WB Rabbit pSer468 Anmelden zum Anzeigen Polyclonal 0
1 ABIN2578777 IHC IHC (p) IP WB Rabbit C-Term Anmelden zum Anzeigen Polyclonal 0
1 ABIN2578781 ICC IF IHC IHC (p) WB Rabbit Internal Region Anmelden zum Anzeigen Polyclonal 0

General

Antigen Nuclear Factor-KB P65 (NFkBP65) Antikörper
Epitop Middle Region
(120), (77), (73), (63), (50), (48), (43), (40), (38), (38), (29), (29), (25), (16), (16), (16), (15), (15), (14), (13), (13), (13), (10), (10), (10), (8), (8), (8), (7), (6), (6), (6), (6), (6), (5), (5), (5), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reaktivität Rind (Kuh), Hund, Human, Maus, Schwein, Ratte (Rattus)
(1213), (737), (567), (70), (67), (52), (30), (24), (19), (16), (12), (8), (6), (5), (4), (1), (1), (1)
Wirt Kaninchen
(1073), (137), (17), (10), (1)
Klonalität
Polyklonal
Konjugat Dieser p65 Antikörper ist unkonjugiert
(30), (29), (23), (19), (18), (17), (17), (12), (12), (12), (11), (8), (8), (8), (8), (8), (8), (8), (8), (4), (4), (3), (3), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1)
Applikation Immunohistochemistry (IHC), Western Blotting (WB)
(930), (552), (391), (281), (213), (187), (105), (101), (85), (37), (29), (20), (17), (12), (12), (6), (6), (6), (5), (5), (4), (2), (1), (1)
Pubmed 1 Publikation vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-p65 Antikörper

Target Details p65 Anwendungsinformationen Handhabung Referenzen für anti-p65 Antikörper (ABIN2779331) Bilder
Blocking Peptide Zu diesem Produkt passt das Blocking Peptide ABIN982837.
Sequenz LVTGAQRPPD PAPAPLGAPG LPNGLLSGDE DFSSIADMDF SALLSQISS
Homologie Cow: 100%, Dog: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rat: 100%
Produktmerkmale This is a rabbit polyclonal antibody against RELA. It was validated on Western Blot using a cell lysate as a positive control.
Reinigung Affinity Purified
Immunogen The immunogen is a synthetic peptide directed towards the middle region of human RELA
Plasmids, Primers & others

Target Details p65

Produktdetails anti-p65 Antikörper Anwendungsinformationen Handhabung Referenzen für anti-p65 Antikörper (ABIN2779331) Bilder zurück nach oben
Antigen
Andere Bezeichnung RELA (NFkBP65 Antibody Abstract)
Hintergrund P65 is a subunit of the nuclear factor kappa-B, a second messenger, which activates the transcription of a number of genes in multiple tissues. The inhibitory effect of I-kappa-B upon NF-kappa-B in the cytoplasm is exerted primarily through the interaction with p65. p65 shows a weak DNA-binding site which could contribute directly to DNA binding in the NF-kappa-B complex. NFKB1 (MIM 164011) or NFKB2 (MIM 164012) is bound to REL (MIM 164910), RELA, or RELB (MIM 604758) to form the NFKB complex. The p50 (NFKB1)/p65 (RELA) heterodimer is the most abundant form of NFKB. The NFKB complex is inhibited by I-kappa-B proteins (NFKBIA, MIM 164008 or NFKBIB, MIM 604495), which inactivate NFKB by trapping it in the cytoplasm. Phosphorylation of serine residues on the I-kappa-B proteins by kinases (IKBKA, MIM 600664, or IKBKB, MIM 603258) marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NFKB complex. Activated NFKB complex translocates into the nucleus and binds DNA at kappa-B-binding motifs such as 5-prime GGGRNNYYCC 3-prime or 5-prime HGGARNYYCC 3-prime (where H is A, C, or T, R is an A or G purine, and Y is a C or T pyrimidine).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-1760 M62399.1 8-1767
Alias Symbols: MGC131774, NFKB3, p65
Protein Interaction Partner: GAN, CCND1, ABCA1, UBC, TCF4, SRSF7, RELA, REL, PRKDC, PLG, PEX1, NFKB2, NFKB1, MUC3A, KRT5, REV1, TXN2, FBXW11, IL1RN, IKBKB, HSPA5, HDAC1, EP300, CREBBP, MAP3K8, CHEK1, CDKN2A, CDK4, SPATA31A3, POTEJ, POTEE, PIWIL4, DIS3L2, DCD, IKBKG, CHUK, PLA2G4A, ST
Protein Size: 551
Molekulargewicht 60 kDa
Gen-ID 5970
NCBI Accession NM_021975, NP_068810
UniProt Q04206
Pathways NF-kappaB Signalweg, RTK Signalweg, T-Zell Rezeptor Signalweg, TLR Signalweg, Fc-epsilon Rezeptor Signalübertragung, Neurotrophin Signalübertragung, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Toll-Like Receptors Cascades

Anwendungsinformationen

Produktdetails anti-p65 Antikörper Target Details p65 Handhabung Referenzen für anti-p65 Antikörper (ABIN2779331) Bilder zurück nach oben
Applikations-hinweise Optimal working dilutions should be determined experimentally by the investigator.
Kommentare

Antigen size: 551 AA

Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-p65 Antikörper Target Details p65 Anwendungsinformationen Referenzen für anti-p65 Antikörper (ABIN2779331) Bilder zurück nach oben
Format Liquid
Konzentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freeze-thaw cycles.
Lagerung -20 °C
Informationen zur Lagerung For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-p65 Antikörper (ABIN2779331)

Produktdetails anti-p65 Antikörper Target Details p65 Anwendungsinformationen Handhabung Bilder zurück nach oben
Allgemeine Veröffentlichungen

Wittwer, Schmitz: "NIK and Cot cooperate to trigger NF-kappaB p65 phosphorylation." in: Biochemical and biophysical research communications, Vol. 371, Issue 2, pp. 294-7, 2008

Bilder

Produktdetails anti-p65 Antikörper Target Details p65 Anwendungsinformationen Handhabung Referenzen für anti-p65 Antikörper (ABIN2779331) zurück nach oben
Bilder des Herstellers
Western Blotting (WB) image for anti-Nuclear Factor-KB P65 (NFkBP65) (Middle Region) antibody (ABIN2779331) Host: Rabbit
Target Name: RELA
Sample Tissue: Human Adult Placenta
Western Blotting (WB) image for anti-Nuclear Factor-KB P65 (NFkBP65) (Middle Region) antibody (ABIN2779331) Host: Rabbit
Target Name: RELA
Sample Tissue: Human Fetal Heart
...
Western Blotting (WB) image for anti-Nuclear Factor-KB P65 (NFkBP65) (Middle Region) antibody (ABIN2779331) Host: Rabbit
Target Name: RELA
Sample Tissue: Human Fetal Lung
A...
Western Blotting (WB) image for anti-Nuclear Factor-KB P65 (NFkBP65) (Middle Region) antibody (ABIN2779331) WB Suggested Anti-RELA Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:312500 Posi...
Western Blotting (WB) image for anti-Nuclear Factor-KB P65 (NFkBP65) (Middle Region) antibody (ABIN2779331) Host: Rabbit Target Name: RELA Sample Type: Human Hela Antibody Dilution: 1.0u...
Immunohistochemistry (IHC) image for anti-Nuclear Factor-KB P65 (NFkBP65) (Middle Region) antibody (ABIN2779331) Rabbit Anti-RELA Antibody Formalin Fixed Paraffin Embedded Tissue: Human Liver Tiss...