anti-Human TLR7 Antikörper für Immunohistochemistry (Paraffin-embedded Sections)

Recommended TLR7 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Toll-Like Receptor 7 (TLR7) Antikörper
  • TLR7-like
  • RGD1563357
  • toll like receptor 7
  • toll-like receptor 7
  • TLR7
  • Tlr7
Epitop
AA 1020-1047, C-Term
27
26
15
12
11
10
10
8
7
6
6
6
5
5
5
5
4
4
3
3
3
2
2
2
2
1
1
1
1
Reaktivität
Human, Maus, Ratte (Rattus)
261
138
42
4
4
3
2
2
2
2
1
1
1
1
1
Wirt
Kaninchen
196
83
2
1
Klonalität
Polyklonal
Konjugat
Dieser TLR7 Antikörper ist unkonjugiert
19
15
12
11
8
6
5
4
4
3
3
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
Applikation
Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
200
101
90
73
47
47
37
14
13
6
5
5
4
2
Optionen
Hersteller
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Produktnummer ABIN3043948
$ 280.00
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
17.138702 ABIN5611472 IHC (p) WB Rabbit IgG AA 465-483 Anmelden zum Anzeigen Polyclonal 0
14.138702 ABIN615823 IHC (p) WB Rabbit IgG AA 900-950 Anmelden zum Anzeigen Polyclonal 0
13 ABIN3044128 IHC (p) WB Rabbit IgG AA 1020-1038, C-Term Anmelden zum Anzeigen Polyclonal 0
12.778215 ABIN2153302 IHC (p) WB Rabbit IgG C-Term Anmelden zum Anzeigen Polyclonal 0
11.5 ABIN718691 IF (p) IHC (p) WB Rabbit IgG AA 500-550 Anmelden zum Anzeigen Polyclonal 1
11.138702 ABIN334260 FACS IHC IHC (fro) IHC (p) WB Rabbit IgG AA 706-728 Anmelden zum Anzeigen Polyclonal 0
11.138702 ABIN214002 ICC IHC IHC (p) WB Rabbit IgG Anmelden zum Anzeigen Polyclonal 0
10 ABIN604913 FACS IHC IHC (p) WB Rabbit IgG AA 900-950 Anmelden zum Anzeigen Polyclonal 0
10 ABIN372519 FACS IHC (fro) IHC (p) WB Rabbit IgG AA 706-728 Anmelden zum Anzeigen Polyclonal 0
10 ABIN5534754 IHC (p) WB Rabbit Ig Fraction AA 98-128, N-Term Anmelden zum Anzeigen Polyclonal 0
10 ABIN5693731 IHC (p) WB Rabbit IgG AA 465-483 Anmelden zum Anzeigen Polyclonal 0
7 ABIN357057 EIA IHC (p) WB Rabbit Ig Fraction N-Term Anmelden zum Anzeigen Polyclonal 2
7 ABIN388342 IHC (p) WB Rabbit Ig Fraction AA 98-128, N-Term Anmelden zum Anzeigen Polyclonal 0
7 ABIN1740124 IHC (p) WB Rabbit IgG AA 900-950 Anmelden zum Anzeigen Polyclonal 0
4 ABIN302882 IF IHC (p) WB Rabbit Middle Region Anmelden zum Anzeigen Polyclonal 0
4 ABIN200019 FACS IHC IHC (fro) IHC (p) WB Rabbit AA 706-728 Anmelden zum Anzeigen Polyclonal 0
4 ABIN1740125 ICC IHC (p) WB Rabbit IgG Anmelden zum Anzeigen Polyclonal 0
4 ABIN1740123 IHC (fro) FACS IHC (p) WB Rabbit IgG AA 706-728 Anmelden zum Anzeigen Polyclonal 0
4 ABIN3029178 IHC (p) WB Rabbit Ig Fraction C-Term Anmelden zum Anzeigen Polyclonal 0
1 ABIN2629317 IHC IHC (p) WB Rabbit IgG AA 1020-1038 Anmelden zum Anzeigen Polyclonal 0

General

Antigen Toll-Like Receptor 7 (TLR7) Antikörper
Epitop AA 1020-1047, C-Term
(27), (26), (15), (12), (11), (10), (10), (8), (7), (6), (6), (6), (5), (5), (5), (5), (4), (4), (3), (3), (3), (2), (2), (2), (2), (1), (1), (1), (1)
Reaktivität Human, Maus, Ratte (Rattus)
(261), (138), (42), (4), (4), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1)
Wirt Kaninchen
(196), (83), (2), (1)
Klonalität
Polyklonal
Konjugat Dieser TLR7 Antikörper ist unkonjugiert
(19), (15), (12), (11), (8), (6), (5), (4), (4), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Applikation Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(200), (101), (90), (73), (47), (47), (37), (14), (13), (6), (5), (5), (4), (2)
Pubmed 1 Publikation vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-TLR7 Antikörper

Target Details TLR7 Anwendungsinformationen Handhabung Referenzen für anti-TLR7 Antikörper (ABIN3043948) Bilder
Verwendungszweck Rabbit IgG polyclonal antibody for Toll-like receptor 7(TLR7) detection. Tested with WB, IHC-P, IHC-F, ICC in Human,Mouse,Rat.
Sequenz QAHPYFWQCL KNALATDNHV AYSQVFKE
Kreuzreaktivität (Details) No cross reactivity with other proteins.
Produktmerkmale Rabbit IgG polyclonal antibody for Toll-like receptor 7(TLR7) detection. Tested with WB, IHC-P, IHC-F, ICC in Human,Mouse,Rat.
Gene Name: toll-like receptor 7
Protein Name: Toll-like receptor 7
Reinigung Immunogen affinity purified.
Immunogen A synthetic peptide corresponding to a sequence at the C-terminus of human TLR7 (1020-1047aa QAHPYFWQCLKNALATDNHVAYSQVFKE), different from the related mouse sequence by two amino acids.
Isotyp IgG
Plasmids, Primers & others

Target Details TLR7

Produktdetails anti-TLR7 Antikörper Anwendungsinformationen Handhabung Referenzen für anti-TLR7 Antikörper (ABIN3043948) Bilder zurück nach oben
Antigen
Andere Bezeichnung TLR7 (TLR7 Antibody Abstract)
Hintergrund TLR7 (Toll-like receptor 7) is protein that in humans is encoded by the TLR7 gene. Orthologs are found in mammals and birds. TLR7 is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is predominantly expressed in lung, placenta, and spleen, and lies in close proximity to another family member, TLR8, on human chromosome X. TLR7 recognises single stranded RNA in endosomes, which is a common feature of viral genomes which are internalised by macrophages.

Synonyms: PRO285 antibody|TLR 7 antibody|Tlr7 antibody|TLR7_HUMAN antibody|Toll like receptor 7 antibody|Toll-like receptor 7 antibody|UNQ248 antibody
Gen-ID 51284
Pathways TLR Signalweg, Activation of Innate immune Response, Toll-Like Receptors Cascades

Anwendungsinformationen

Produktdetails anti-TLR7 Antikörper Target Details TLR7 Handhabung Referenzen für anti-TLR7 Antikörper (ABIN3043948) Bilder zurück nach oben
Applikations-hinweise WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, The detection limit for TLR7 is approximately 0.1 ng/lane under reducing conditions.
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
IHC-F: Concentration: 0.5-1 μg/mL, Tested Species: Human
ICC: Concentration: 0.5-1 μg/mL, Tested Species: Human
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.
Kommentare

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P), IHC(F) and ICC.

Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-TLR7 Antikörper Target Details TLR7 Anwendungsinformationen Referenzen für anti-TLR7 Antikörper (ABIN3043948) Bilder zurück nach oben
Format Lyophilized
Rekonstitution Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
Konzentration 500 μg/mL
Buffer Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freezing and thawing.
Lagerung 4 °C/-20 °C
Informationen zur Lagerung At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Referenzen für anti-TLR7 Antikörper (ABIN3043948)

Produktdetails anti-TLR7 Antikörper Target Details TLR7 Anwendungsinformationen Handhabung Bilder zurück nach oben
Produkt verwendet in:

Esancy, Condon, Feng, Kimball, Curtright, Dhaka: "A zebrafish and mouse model for selective pruritus via direct activation of TRPA1." in: eLife, Vol. 7, 2018

Bilder

Produktdetails anti-TLR7 Antikörper Target Details TLR7 Anwendungsinformationen Handhabung Referenzen für anti-TLR7 Antikörper (ABIN3043948) zurück nach oben
Bilder des Herstellers
Immunohistochemistry (IHC) image for anti-Toll-Like Receptor 7 (TLR7) (AA 1020-1047), (C-Term) antibody (ABIN3043948) Anti- TLR7 Picoband antibody, IHC(P) IHC(P): Human Placenta Tissue
Immunohistochemistry (IHC) image for anti-Toll-Like Receptor 7 (TLR7) (AA 1020-1047), (C-Term) antibody (ABIN3043948) Anti- TLR7 Picoband antibody, IHC(P) IHC(P): Rat Thymus Tissue
Immunohistochemistry (IHC) image for anti-Toll-Like Receptor 7 (TLR7) (AA 1020-1047), (C-Term) antibody (ABIN3043948) Anti- TLR7 Picoband antibody, IHC(F) IHC(F): Human Placenta Tissue
Western Blotting (WB) image for anti-Toll-Like Receptor 7 (TLR7) (AA 1020-1047), (C-Term) antibody (ABIN3043948) Anti- TLR7 Picoband antibody, Western blotting All lanes: Anti TLR7 at 0.5ug/ml Lane...
Immunohistochemistry (IHC) image for anti-Toll-Like Receptor 7 (TLR7) (AA 1020-1047), (C-Term) antibody (ABIN3043948) Anti- TLR7 Picoband antibody, ICC ICC: A549 Cell
Immunohistochemistry (IHC) image for anti-Toll-Like Receptor 7 (TLR7) (AA 1020-1047), (C-Term) antibody (ABIN3043948) Anti- TLR7 Picoband antibody, IHC(P) IHC(P): Mouse Thymus Tissue
Western Blotting (WB) image for anti-Toll-Like Receptor 7 (TLR7) (AA 1020-1047), (C-Term) antibody (ABIN3043948) Anti- TLR7 Picoband antibody, Western blottingAll lanes: Anti TLR7 at 0.5ug/ml Lane ...