anti-Human TLR7 Antikörper für Enzyme Immunoassay

Recommended TLR7 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Toll-Like Receptor 7 (TLR7) Antikörper
  • TLR7-like
  • RGD1563357
  • toll like receptor 7
  • toll-like receptor 7
  • TLR7
  • Tlr7
Epitop
N-Term
29
27
15
14
12
10
9
9
7
6
6
6
6
5
5
5
4
4
3
3
2
2
2
2
1
1
1
1
1
1
Reaktivität
Human, Maus
269
139
42
4
4
3
2
2
2
2
1
1
1
1
1
Wirt
Kaninchen
199
90
2
1
Klonalität
Polyklonal
Konjugat
Dieser TLR7 Antikörper ist unkonjugiert
19
15
12
11
8
6
5
5
4
4
4
3
3
3
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
Applikation
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
205
100
96
76
51
50
39
15
13
6
5
5
3
2
Hersteller
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Hersteller Produkt- Nr.
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Bilder

Produktnummer ABIN357057
$ 390.50
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
1 ABIN5555340 EIA IF WB Rabbit IgG Middle Region Anmelden zum Anzeigen Polyclonal 0
1 ABIN121174 EIA WB Mouse IgG1 AA 451-500 Anmelden zum Anzeigen 4F4 3
1 ABIN320380 EIA WB Mouse IgG1 AA 451-500 Anmelden zum Anzeigen 4F4 0

General

Antigen Toll-Like Receptor 7 (TLR7) Antikörper
Epitop N-Term
(29), (27), (15), (14), (12), (10), (9), (9), (7), (6), (6), (6), (6), (5), (5), (5), (4), (4), (3), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1)
Reaktivität Human, Maus
(269), (139), (42), (4), (4), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1)
Wirt Kaninchen
(199), (90), (2), (1)
Klonalität
Polyklonal
Konjugat Dieser TLR7 Antikörper ist unkonjugiert
(19), (15), (12), (11), (8), (6), (5), (5), (4), (4), (4), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Applikation Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(205), (100), (96), (76), (51), (50), (39), (15), (13), (6), (5), (5), (3), (2)
Pubmed 2 Publikationen vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-TLR7 Antikörper

Target Details TLR7 Anwendungsinformationen Handhabung Referenzen für anti-TLR7 Antikörper (ABIN357057) Bilder
Spezifität This antibody detects TLR7 at N-term.
Kreuzreaktivität (Details) Species reactivity (tested):Human and Mouse.
Reinigung Protein Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Immunogen This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-term region of human TLR7.
Isotyp Ig Fraction
Plasmids, Primers & others

Target Details TLR7

Produktdetails anti-TLR7 Antikörper Anwendungsinformationen Handhabung Referenzen für anti-TLR7 Antikörper (ABIN357057) Bilder zurück nach oben
Antigen
Andere Bezeichnung TLR7 (TLR7 Antibody Abstract)
Hintergrund The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. TLR7 is predominantly expressed in lung, placenta, and spleen, and lies in close proximity to another family member, TLR8, on chromosome X.Synonyms: Toll-like receptor 7
Molekulargewicht 120921 Da
Gen-ID 51284, 9606
UniProt Q9NYK1
Pathways TLR Signalweg, Activation of Innate immune Response, Toll-Like Receptors Cascades

Anwendungsinformationen

Produktdetails anti-TLR7 Antikörper Target Details TLR7 Handhabung Referenzen für anti-TLR7 Antikörper (ABIN357057) Bilder zurück nach oben
Applikations-hinweise ELISA: 1/1,000. Western blot: 1/100-1/500. Immunohistochemistry: 1/50-1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-TLR7 Antikörper Target Details TLR7 Anwendungsinformationen Referenzen für anti-TLR7 Antikörper (ABIN357057) Bilder zurück nach oben
Format Liquid
Konzentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) Sodium Azide as preservative
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freezing and thawing.
Lagerung 4 °C/-20 °C
Informationen zur Lagerung Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Referenzen für anti-TLR7 Antikörper (ABIN357057)

Produktdetails anti-TLR7 Antikörper Target Details TLR7 Anwendungsinformationen Handhabung Bilder zurück nach oben
Allgemeine Veröffentlichungen

Clark, Gurney, Abaya, Baker, Baldwin, Brush, Chen, Chow, Chui, Crowley, Currell, Deuel, Dowd, Eaton, Foster, Grimaldi, Gu, Hass, Heldens, Huang, Kim, Klimowski, Jin, Johnson, Lee, Lewis, Liao, Mark et al.: "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. ..." in: Genome research, Vol. 13, Issue 10, pp. 2265-70, 2003

Ito, Amakawa, Kaisho, Hemmi, Tajima, Uehira, Ozaki, Tomizawa, Akira, Fukuhara: "Interferon-alpha and interleukin-12 are induced differentially by Toll-like receptor 7 ligands in human blood dendritic cell subsets." in: The Journal of experimental medicine, Vol. 195, Issue 11, pp. 1507-12, 2002

Bilder

Produktdetails anti-TLR7 Antikörper Target Details TLR7 Anwendungsinformationen Handhabung Referenzen für anti-TLR7 Antikörper (ABIN357057) zurück nach oben
Bilder des Herstellers
 image for anti-Toll-Like Receptor 7 (TLR7) (N-Term) antibody (ABIN357057) anti-Toll-Like Receptor 7 (TLR7) (N-Term) antibody
 image for anti-Toll-Like Receptor 7 (TLR7) (N-Term) antibody (ABIN357057) anti-Toll-Like Receptor 7 (TLR7) (N-Term) antibody (Image 2)