anti-Human TLR1 Antikörper für Enzyme Immunoassay

Recommended TLR1 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Toll-Like Receptor 1 (TLR1) Antikörper
  • CD281
  • TIL
  • TIL. LPRS5
  • rsc786
  • toll like receptor 1
  • toll-like receptor 1
  • TLR1
  • Tlr1
Epitop
C-Term
26
11
11
7
6
5
5
4
3
3
2
2
2
2
2
2
2
2
1
1
1
1
Reaktivität
Human, Maus
178
90
42
1
Wirt
Kaninchen
140
47
17
1
Klonalität
Polyklonal
Konjugat
Dieser TLR1 Antikörper ist unkonjugiert
18
17
16
5
5
3
1
1
1
1
1
1
1
1
1
1
1
1
Applikation
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
131
78
75
52
36
14
14
13
13
12
11
7
5
3
2
Hersteller
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Hersteller Produkt- Nr.
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Bilder

Produktnummer ABIN357041
$ 390.50
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
1 ABIN1106187 EIA IHC (fro) FACS IF IHC (p) Biotin Mouse IgG1 Anmelden zum Anzeigen GD2-F4 7
1 ABIN1106186 Func EIA IHC (fro) FACS IF IHC (p) Mouse IgG1 Anmelden zum Anzeigen GD2-F4 5
1 ABIN5555327 EIA IHC (p) WB Rabbit IgG N-Term Anmelden zum Anzeigen Polyclonal 0
1 ABIN5555328 EIA IF WB Rabbit IgG Center Anmelden zum Anzeigen Polyclonal 0
1 ABIN127125 EIA WB Goat Anmelden zum Anzeigen Polyclonal 0

General

Antigen Toll-Like Receptor 1 (TLR1) Antikörper
Epitop C-Term
(26), (11), (11), (7), (6), (5), (5), (4), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1)
Reaktivität Human, Maus
(178), (90), (42), (1)
Wirt Kaninchen
(140), (47), (17), (1)
Klonalität
Polyklonal
Konjugat Dieser TLR1 Antikörper ist unkonjugiert
(18), (17), (16), (5), (5), (3), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Applikation Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(131), (78), (75), (52), (36), (14), (14), (13), (13), (12), (11), (7), (5), (3), (2)
Pubmed 2 Publikationen vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-TLR1 Antikörper

Target Details TLR1 Anwendungsinformationen Handhabung Referenzen für anti-TLR1 Antikörper (ABIN357041) Bilder
Spezifität This antibody detects TLR1 at C-term.
Reinigung Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
Immunogen This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of Mouse TLR1.
Isotyp Ig Fraction
Plasmids, Primers & others

Target Details TLR1

Produktdetails anti-TLR1 Antikörper Anwendungsinformationen Handhabung Referenzen für anti-TLR1 Antikörper (ABIN357041) Bilder zurück nach oben
Antigen
Andere Bezeichnung CD281 / TLR1 (TLR1 Antibody Abstract)
Hintergrund Higher animals establish host defense by orchestrating innate and adaptive immunity. This is mediated by professional antigen presenting cells, i.e. dendritic cells (DCs). DCs can incorporate pathogens, produce a variety of cytokines, maturate, and present pathogen-derived peptides to T cells, thereby inducing T cell activation and differentiation. These responses are triggered by microbial recognition through type I transmembrane proteins, Toll-like receptors (TLRs) on DCs. TLRs consist of ten members and each TLR is involved in recognizing a variety of microorganism-derived molecular structures. TLR ligands include cell wall components, proteins, nucleic acids, and synthetic chemical compounds, all of which can activate DCs as immune adjuvants. Each TLR can activate DCs in a similar, but distinct manner. For example, TLRs can be divided into subgroups according to their type I interferon (IFN) inducing ability. TLR2 cannot induce IFN-alpha or IFN-beta, but TLR4 can lead to IFN-beta production. Meanwhile, TLR3, TLR7, and TLR9 can induce both IFN-alpha and IFN-beta. Recent evidences suggest that cytoplamic adapters for TLRs are especially crucial for this functional heterogeneity.Synonyms: KIAA0012, TIL, Toll-like receptor 1, Toll/interleukin-1 receptor-like protein
Gen-ID 21897, 10090
UniProt Q9EPQ1
Pathways TLR Signalweg, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades

Anwendungsinformationen

Produktdetails anti-TLR1 Antikörper Target Details TLR1 Handhabung Referenzen für anti-TLR1 Antikörper (ABIN357041) Bilder zurück nach oben
Applikations-hinweise ELISA: 1/1,000. Western blot: 1/100-1/500. Immunohistochemistry: 1/50-1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-TLR1 Antikörper Target Details TLR1 Anwendungsinformationen Referenzen für anti-TLR1 Antikörper (ABIN357041) Bilder zurück nach oben
Format Liquid
Konzentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) Sodium Azide as preservative.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freezing and thawing.
Lagerung 4 °C/-20 °C
Informationen zur Lagerung Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Referenzen für anti-TLR1 Antikörper (ABIN357041)

Produktdetails anti-TLR1 Antikörper Target Details TLR1 Anwendungsinformationen Handhabung Bilder zurück nach oben
Allgemeine Veröffentlichungen

Hajjar, OMahony, Ozinsky, Underhill, Aderem, Klebanoff, Wilson: "Cutting edge: functional interactions between toll-like receptor (TLR) 2 and TLR1 or TLR6 in response to phenol-soluble modulin." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 166, Issue 1, pp. 15-9, 2001

Ozinsky, Underhill, Fontenot, Hajjar, Smith, Wilson, Schroeder, Aderem: "The repertoire for pattern recognition of pathogens by the innate immune system is defined by cooperation between toll-like receptors." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 97, Issue 25, pp. 13766-71, 2000

Bilder

Produktdetails anti-TLR1 Antikörper Target Details TLR1 Anwendungsinformationen Handhabung Referenzen für anti-TLR1 Antikörper (ABIN357041) zurück nach oben
Bilder des Herstellers
 image for anti-Toll-Like Receptor 1 (TLR1) (C-Term) antibody (ABIN357041) anti-Toll-Like Receptor 1 (TLR1) (C-Term) antibody
 image for anti-Toll-Like Receptor 1 (TLR1) (C-Term) antibody (ABIN357041) anti-Toll-Like Receptor 1 (TLR1) (C-Term) antibody (Image 2)