anti-Ratte (Rattus) TIRAP Antikörper für ELISA

Recommended TIRAP Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Toll-Interleukin 1 Receptor (TIR) Domain Containing Adaptor Protein (TIRAP) Antikörper
  • mal
  • wyatt
  • BACTS1
  • Mal
  • MyD88-2
  • AA407980
  • C130027E04Rik
  • Tlr4ap
  • Wyatt
  • toll-interleukin 1 receptor (TIR) domain containing adaptor protein
  • TIR domain containing adaptor protein
  • toll-interleukin 1 receptor (TIR) domain containing adaptor protein L homeolog
  • toll-interleukin 1 receptor (TIR) domain-containing adaptor protein
  • tirap
  • TIRAP
  • tirap.L
  • Tirap
Epitop
C-Term
29
22
15
5
5
4
4
3
3
3
2
2
2
1
1
1
1
1
1
1
1
1
Reaktivität
Human, Maus, Ratte (Rattus)
149
71
38
2
2
2
1
1
1
1
Wirt
Kaninchen
114
31
5
5
Klonalität
Polyklonal
Konjugat
Dieser TIRAP Antikörper ist unkonjugiert
4
4
4
2
2
2
2
2
2
2
2
2
2
2
2
2
2
Applikation
Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
109
60
49
31
26
7
4
3
2
1
Hersteller
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Hersteller Produkt- Nr.
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Mehr erfahren

Produktnummer ABIN1003284
$ 523.71
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
1 ABIN198092 ELISA IHC IHC (p) WB Rabbit IgG C-Term Anmelden zum Anzeigen Polyclonal 0
1 ABIN1030739 IHC ELISA WB Rabbit C-Term Anmelden zum Anzeigen Polyclonal 0
1 ABIN1093594 IHC ELISA WB Rabbit IgG Anmelden zum Anzeigen Polyclonal 0
1 ABIN1887377 IHC ELISA WB Rabbit C-Term Anmelden zum Anzeigen Polyclonal 0

General

Antigen Toll-Interleukin 1 Receptor (TIR) Domain Containing Adaptor Protein (TIRAP) Antikörper
Epitop C-Term
(29), (22), (15), (5), (5), (4), (4), (3), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reaktivität Human, Maus, Ratte (Rattus)
(149), (71), (38), (2), (2), (2), (1), (1), (1), (1)
Wirt Kaninchen
(114), (31), (5), (5)
Klonalität
Polyklonal
Konjugat Dieser TIRAP Antikörper ist unkonjugiert
(4), (4), (4), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Applikation Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
(109), (60), (49), (31), (26), (7), (4), (3), (2), (1)
Pubmed 4 Publikationen vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-TIRAP Antikörper

Target Details TIRAP Anwendungsinformationen Handhabung Referenzen für anti-TIRAP Antikörper (ABIN1003284) Bilder
Blocking Peptide Zu diesem Produkt passt das Blocking Peptide ABIN1003892.
Reinigung Ion exchange chromatography purified.
Immunogen Rabbit polyclol TIRAP antibody was raised against a peptide corresponding to 15 amino acids near the C-terminus of mouse TIRAP (GenBank accession no. AAL05628).
Isotyp IgG
Plasmids, Primers & others

Target Details TIRAP

Produktdetails anti-TIRAP Antikörper Anwendungsinformationen Handhabung Referenzen für anti-TIRAP Antikörper (ABIN1003284) Bilder zurück nach oben
Antigen
Andere Bezeichnung TIRAP (Toll-Like Receptor Adaptor Protein) (TIRAP Antibody Abstract)
Hintergrund Toll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. These proteins act through adaptor molecules such as TIRAP and MyD88 to activate various kinases and transcription factors. In TIRAP-deficient mice, TLR signaling in response to TLR2 ligands (using either TLR1 and TLR6 as co-receptors) is totally abolished, suggesting that MyD88 and TIRAP work together and are both required for TLR2 signaling. Furthermore, these mice are also resistant to the toxic effects of LPS and show defects in NF-kappaB and MAP kinase activation, suggesting that TIRAP is also involed in TLR4 signaling.
Pathways TLR Signalweg, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades

Anwendungsinformationen

Produktdetails anti-TIRAP Antikörper Target Details TIRAP Handhabung Referenzen für anti-TIRAP Antikörper (ABIN1003284) Bilder zurück nach oben
Applikations-hinweise TIRAP antibody can be used for detection of TIRAP by Western blot at 0.5 to 2 µg/ml. (Optimal dilution should be determined by user.) Antibody can also be used for immunohistochemistry and ELISA and might be suited for other applications not tested so far.
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-TIRAP Antikörper Target Details TIRAP Anwendungsinformationen Referenzen für anti-TIRAP Antikörper (ABIN1003284) Bilder zurück nach oben
Format Liquid
Buffer Antibody is supplied in PBS containing 0.02% sodium azide.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Antibody can be stored at 4 °C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. During shipment, small volumes of antibody will occasionally become entrapped in the seal of the product vial. For products with volumes of 200 myl or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container’s cap.
Lagerung 4 °C
Haltbarkeit 12 months

Referenzen für anti-TIRAP Antikörper (ABIN1003284)

Produktdetails anti-TIRAP Antikörper Target Details TIRAP Anwendungsinformationen Handhabung Bilder zurück nach oben
Allgemeine Veröffentlichungen

Vogel, Fitzgerald, Fenton: "TLRs: differential adapter utilization by toll-like receptors mediates TLR-specific patterns of gene expression." in: Molecular interventions, Vol. 3, Issue 8, pp. 466-77, 2004

Takeda, Kaisho, Akira: "Toll-like receptors." in: Annual review of immunology, Vol. 21, pp. 335-76, 2003

Janeway, Medzhitov: "Innate immune recognition." in: Annual review of immunology, Vol. 20, pp. 197-216, 2002

Produkt verwendet in:

ONeill, Fitzgerald, Bowie: "The Toll-IL-1 receptor adaptor family grows to five members." in: Trends in immunology, Vol. 24, Issue 6, pp. 286-90, 2003