anti-Maus TANK-Binding Kinase 1 Antikörper für Enzyme Immunoassay

Recommended TANK-Binding Kinase 1 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
TANK-Binding Kinase 1 (TBK1) Antikörper
  • nak
  • t2k
  • TBK1
  • wu:fk70c05
  • zgc:136548
  • NAK
  • T2K
  • 1200008B05Rik
  • AI462036
  • AW048562
  • TANK binding kinase 1 L homeolog
  • TANK binding kinase 1
  • TANK-binding kinase 1
  • tbk1.L
  • TBK1
  • tbk1
  • Tbk1
Epitop
C-Term
18
18
17
11
7
7
6
4
4
3
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
Reaktivität
Human, Maus
132
84
49
27
26
10
10
9
8
5
5
4
3
2
2
2
2
1
1
Wirt
Kaninchen
104
34
13
Klonalität
Polyklonal
Konjugat
Unkonjugiert
10
10
9
7
5
5
3
3
1
1
1
1
1
1
1
1
1
Applikation
Enzyme Immunoassay (EIA), Immunofluorescence (IF), Western Blotting (WB)
133
70
62
31
24
17
9
6
3
2
2
1
1
Hersteller
Anmelden zum Anzeigen
Hersteller Produkt- Nr.
Anmelden zum Anzeigen
Request

Produkt kostenlos erhalten?

Für Ihre Validierungsdaten erstatten wir Ihnen den vollen Kaufpreis. Ich möchte dieses Produkt validieren

Mehr erfahren

Produktnummer ABIN5555030
$ 474.10
Zzgl. Versandkosten $45.00

General

Antigen TANK-Binding Kinase 1 (TBK1) Antikörper
Epitop C-Term
(18), (18), (17), (11), (7), (7), (6), (4), (4), (3), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reaktivität Human, Maus
(132), (84), (49), (27), (26), (10), (10), (9), (8), (5), (5), (4), (3), (2), (2), (2), (2), (1), (1)
Wirt Kaninchen
(104), (34), (13)
Klonalität
Polyklonal
Konjugat Unkonjugiert
(10), (10), (9), (7), (5), (5), (3), (3), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Applikation Enzyme Immunoassay (EIA), Immunofluorescence (IF), Western Blotting (WB)
(133), (70), (62), (31), (24), (17), (9), (6), (3), (2), (2), (1), (1)
Hersteller Anmelden zum Anzeigen

Produktdetails

Antigendetails Anwendungsinformationen Handhabung Bilder
Spezifität This antibody detects TBK1 at C-term. It has no cross response to IKKa, IKKb, IKKy, or IKKe.
Kreuzreaktivität (Details) Species reactivity (tested):Human, mouse
Reinigung Peptide affinity chromatography
Immunogen Peptide from C-term of human NAK / TBK1 (Cat. No. 2351P)
Isotyp IgG

Antigendetails

Produktdetails Anwendungsinformationen Handhabung Bilder zurück nach oben
Antigen
Andere Bezeichnung TBK1 (TBK1 Antibody Abstract)
Hintergrund Nuclear factor kappa B (NF-kappaB) is a ubiquitous transcription factor and an essential mediator of gene expression during activation of immune and inflammatory responses. NF-kappaB mediates the expression of a great variety of genes in response to extracellular stimuli. NF-kappaB is associated with IkappaB proteins in the cell cytoplasm, which inhibit NF-kappaB activity. Phosphorylation of I-kappaB by IkappaB kinase (IKK) complex leads to degradation of I-kappaB and activation of NF-kappaB. The IKK complex contains IKKalpha, IKKbeta, and IKKgamma. A novel IKK related kinase was recently identified and designated TBK1 (TANK-binding kinase 1), NAK (NF-kappaB-activating kinase), and T2K (1-3). NAK/TBK1 activates IKKbeta through direct phosphorylation. NAK/TBK1 is activated by growth factors and PMA and mediates IKK and NF-kappaB activation in response to growth factors (2). NAK/TBK1 functions upstream of NIK and the IKK complex (1,2). NAK/TBK1 is also critical in protecting embryonic liver from apoptosis (3).Synonyms: NAK, NF-kappa-B-activating kinase, T2K, TANK-binding kinase 1
Gen-ID 29110
NCBI Accession NP_037386
UniProt Q9UHD2
Pathways TLR Signalweg, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades

Anwendungsinformationen

Produktdetails Antigendetails Handhabung Bilder zurück nach oben
Applikations-hinweise ELISA. Western blot: 0.5 - 1 μg/mL, an 84 kDa band should be detected. Immunocytochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails Antigendetails Anwendungsinformationen Bilder zurück nach oben
Buffer PBS containing 0.02 % sodium azide
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freezing and thawing.
Lagerung 4 °C/-20 °C
Informationen zur Lagerung Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.