anti-Human IRAK3 Antikörper für Enzyme Immunoassay

Recommended IRAK3 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Interleukin-1 Receptor-Associated Kinase 3 (IRAK3) Antikörper
  • IRAK3
  • si:dkey-150i15.2
  • ASRT5
  • IRAKM
  • IrakM
  • 4833428C18Rik
  • AI563835
  • IRAK-M
  • interleukin 1 receptor associated kinase 3
  • interleukin-1 receptor-associated kinase 3
  • IRAK3
  • irak3
  • Irak3
Reaktivität
Human
127
59
41
2
2
2
2
1
1
1
Wirt
Kaninchen
126
21
17
Klonalität
Polyklonal
Konjugat
Dieser IRAK3 Antikörper ist unkonjugiert
6
6
5
5
5
5
Applikation
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
152
93
48
20
19
17
8
5
4
2
2
1
Hersteller
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Hersteller Produkt- Nr.
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Bilder

Produktnummer ABIN317722
$ 390.50
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
4 ABIN360119 EIA WB Rabbit Ig Fraction N-Term Anmelden zum Anzeigen Polyclonal 2
1 ABIN5554900 EIA IHC (p) WB Rabbit IgG Anmelden zum Anzeigen Polyclonal 0

General

Antigen Interleukin-1 Receptor-Associated Kinase 3 (IRAK3) Antikörper
Reaktivität Human
(127), (59), (41), (2), (2), (2), (2), (1), (1), (1)
Wirt Kaninchen
(126), (21), (17)
Klonalität
Polyklonal
Konjugat Dieser IRAK3 Antikörper ist unkonjugiert
(6), (6), (5), (5), (5), (5)
Applikation Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(152), (93), (48), (20), (19), (17), (8), (5), (4), (2), (2), (1)
Hersteller Anmelden zum Anzeigen

Produktdetails anti-IRAK3 Antikörper

Target Details IRAK3 Anwendungsinformationen Handhabung Bilder
Spezifität This antibody detects endogenous levels of IRAK-M protein.(region surrounding Gln649)
Kreuzreaktivität (Details) Species reactivity (tested):Human.
Reinigung Affinity-Chromatography using epitope-specific immunogen.
Plasmids, Primers & others

Target Details IRAK3

Produktdetails anti-IRAK3 Antikörper Anwendungsinformationen Handhabung Bilder zurück nach oben
Antigen
Andere Bezeichnung IRAK3 (IRAK3 Antibody Abstract)
Hintergrund Interleukin-1 receptor (IL1R)-associated kinases (IRAKs) are important mediators in the signal transduction of Toll-like receptor (TLR) and IL1R family members, collectively referred to as TIRs. Binding of IL-1 to its cognate receptor results in the activation of the NFκB signaling pathway. A 100 kDa IL-1- dependent kinase termed IRAK-1 (for IL-1 receptor- associated kinase 1) coimmunoprecipitates with activated IL-1RI and is implicated as an upstream mediator of NFκB activation. A related Drosophila protein, Pelle, is a known upstream activator of Dorsal, the Drosophila homolog of NFκB. IRAK-2 is a proximal mediator of IL1, a component of the IL1R signaling complex, and is required for IL1R-induced NFκB activation. IRAK-4, like IRAK-1 and Pelle, has auto- and cross-phosphorylation kinase activity. IRAK-4 is strongly expressed in kidney and is also found in lung, testis, small intestine, breast, liver, and placenta. In contrast to the other IRAKs that are expressed in most cell types, IRAK-M is restricted to monocytic cells. IRAK-M mRNA transcripts are found predominantly in PBL and the monocytic cell lines U937 and THP-1.Synonyms: IL-1 receptor-associated kinase M, IRAK-3, IRAK-M, Interleukin-1 receptor-associated kinase 3
Molekulargewicht approx. 68 kDa
Gen-ID 11213
NCBI Accession NP_001135995
UniProt Q9Y616
Pathways TLR Signalweg, Activation of Innate immune Response, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades

Anwendungsinformationen

Produktdetails anti-IRAK3 Antikörper Target Details IRAK3 Handhabung Bilder zurück nach oben
Applikations-hinweise ELISA: 1: 20000approx. 1: 40000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-IRAK3 Antikörper Target Details IRAK3 Anwendungsinformationen Bilder zurück nach oben
Konzentration 1.0 mg/mL
Buffer Phosphate buffered saline (PBS), pH ~7.2 with 0.05 % Sodium Azide as preservative.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freezing and thawing.
Lagerung 4 °C/-20 °C
Informationen zur Lagerung Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Bilder

Produktdetails anti-IRAK3 Antikörper Target Details IRAK3 Anwendungsinformationen Handhabung zurück nach oben
Bilder des Herstellers
 image for anti-Interleukin-1 Receptor-Associated Kinase 3 (IRAK3) antibody (ABIN317722) anti-Interleukin-1 Receptor-Associated Kinase 3 (IRAK3) antibody
 image for anti-Interleukin-1 Receptor-Associated Kinase 3 (IRAK3) antibody (ABIN317722) anti-Interleukin-1 Receptor-Associated Kinase 3 (IRAK3) antibody (Image 2)