anti-Human IRAK2 Antikörper für Immunohistochemistry (Frozen Sections)

Recommended IRAK2 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Interleukin-1 Receptor-Associated Kinase 2 (IRAK2) Antikörper
  • IRAK-2
  • 6330415L08Rik
  • AI649099
  • interleukin 1 receptor associated kinase 2
  • interleukin-1 receptor-associated kinase 2
  • IRAK2
  • Irak2
Epitop
AA 546-564
49
15
11
11
10
10
8
7
7
5
5
5
3
2
2
2
2
2
1
1
Reaktivität
Human
188
54
33
2
2
1
1
1
1
1
1
1
Wirt
Kaninchen
183
27
Klonalität
Polyklonal
Konjugat
Dieser IRAK2 Antikörper ist unkonjugiert
10
10
7
6
6
6
1
1
1
1
1
1
1
1
1
1
1
Applikation
Immunohistochemistry (Frozen Sections) (IHC (fro)), Western Blotting (WB)
194
103
52
29
20
20
13
8
4
4
3
2
Optionen
Hersteller
Anmelden zum Anzeigen
Hersteller Produkt- Nr.
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Bilder

Produktnummer ABIN187751
$ 776.60
Zzgl. Versandkosten $45.00

General

Antigen Interleukin-1 Receptor-Associated Kinase 2 (IRAK2) Antikörper
Epitop AA 546-564
(49), (15), (11), (11), (10), (10), (8), (7), (7), (5), (5), (5), (3), (2), (2), (2), (2), (2), (1), (1)
Reaktivität Human
(188), (54), (33), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Wirt Kaninchen
(183), (27)
Klonalität
Polyklonal
Konjugat Dieser IRAK2 Antikörper ist unkonjugiert
(10), (10), (7), (6), (6), (6), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Applikation Immunohistochemistry (Frozen Sections) (IHC (fro)), Western Blotting (WB)
(194), (103), (52), (29), (20), (20), (13), (8), (4), (4), (3), (2)
Hersteller Anmelden zum Anzeigen

Produktdetails anti-IRAK2 Antikörper

Target Details IRAK2 Anwendungsinformationen Handhabung Bilder
Spezifität Binds IRAK2. Anti-IRAK2 has no cross response to IRAK. Species Reactivity: Human, other species not tested.
Immunogen A peptide corresponding to amino acid 546 to 564 of human IRAK2.
Plasmids, Primers & others

Target Details IRAK2

Produktdetails anti-IRAK2 Antikörper Anwendungsinformationen Handhabung Bilder zurück nach oben
Antigen
Andere Bezeichnung IRAK2 (IRAK2 Antibody Abstract)
Hintergrund The pro-inflammatory cytokine IL-1 induces cellular response through two subunits of its receptor, IL-1 receptor I (IL-1RI) and IL-1 receptor accessory protein (IL-1RAcP). IL-1 receptor-associated kinase (IRAK) mediates activation of NF-kappabeta, which is a pivotal transcription factor mediating inflammatory and immune response. A novel member in the IRAK/Pelle family was recently identified and designated IRAK2. Both IRAK and IRAK2 recruit to the subunits of the IL-1R complex after IL-1 binding and lead to NF-kappabeta activation. IRAKs also associate with Toll like receptor (TLR) and the dominant negative mutants of IRAKs inhibit LPS-induced NF-kB activation. Members in IRAK/Pelle family play a central role in IL-1R and TLR mediated inflammatory response. IRAK2 is expressed in a variety of human tissues.
Pathways TLR Signalweg, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades

Anwendungsinformationen

Produktdetails anti-IRAK2 Antikörper Target Details IRAK2 Handhabung Bilder zurück nach oben
Applikations-hinweise Immunohistochemistry: Use at 2 µg/mL Western blot: Use at a 1:500 to 1:1,000 dilution. The optimal dilution for a specific application should be determined by the researcher.
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-IRAK2 Antikörper Target Details IRAK2 Anwendungsinformationen Bilder zurück nach oben
Buffer Immunoaffinity chromatography purified IgG, 100 µg in 200 µL of PBS containing 0.02% sodium azide.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung 4 °C

Bilder

Produktdetails anti-IRAK2 Antikörper Target Details IRAK2 Anwendungsinformationen Handhabung zurück nach oben
Bilder des Herstellers
Western Blotting (WB) image for anti-Interleukin-1 Receptor-Associated Kinase 2 (IRAK2) (AA 546-564) antibody (ABIN187751) anti-Interleukin-1 Receptor-Associated Kinase 2 (IRAK2) (AA 546-564) antibody