anti-Ratte (Rattus) CD36 Antikörper für Functional Studies

Recommended CD36 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
CD36 Molecule (thrombospondin Receptor) (CD36) Antikörper
  • BDPLT10
  • CHDS7
  • FAT
  • GP3B
  • GP4
  • GPIV
  • PASIV
  • SCARB3
  • Fat
  • Scarb3
  • GPIIIB
  • PAS-4
  • zgc:92513
  • CD36 molecule
  • CD36 molecule (thrombospondin receptor)
  • CD36
  • Cd36
  • cd36
Reaktivität
Maus, Ratte (Rattus)
363
151
91
8
7
4
4
3
3
3
1
Wirt
Maus
253
139
48
12
2
Klonalität
Monoklonal
Konjugat
Dieser CD36 Antikörper ist unkonjugiert
53
27
21
20
10
9
8
5
5
5
3
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
Applikation
Functional Studies (Func), Immunofluorescence (IF), Immunoprecipitation (IP), Western Blotting (WB)
292
143
134
90
65
40
40
39
37
28
14
3
3
3
3
3
3
2
2
2
2
1
1
1
1
Hersteller
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Produktnummer ABIN1106326
$ 368.50
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
1 ABIN2689209 Func FACS IF IP Mouse IgA, kappa Anmelden zum Anzeigen CRF D 3
1 ABIN343926 FACS Func Mouse IgA Anmelden zum Anzeigen JC63-1 0

General

Antigen CD36 Molecule (thrombospondin Receptor) (CD36) Antikörper
Reaktivität Maus, Ratte (Rattus)
(363), (151), (91), (8), (7), (4), (4), (3), (3), (3), (1)
Wirt Maus
(253), (139), (48), (12), (2)
Klonalität (Klon)
Monoklonal   ( )
Konjugat Dieser CD36 Antikörper ist unkonjugiert
(53), (27), (21), (20), (10), (9), (8), (5), (5), (5), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1)
Applikation Functional Studies (Func), Immunofluorescence (IF), Immunoprecipitation (IP), Western Blotting (WB)
(292), (143), (134), (90), (65), (40), (40), (39), (37), (28), (14), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (1), (1), (1), (1)
Pubmed 5 Publikationen vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-CD36 Antikörper

Target Details CD36 Anwendungsinformationen Handhabung Referenzen für anti-CD36 Antikörper (ABIN1106326) Bilder
Spezifität Monoclonal antibody CRF D-2712 (also known as JC63.1 or 63) reacts with mouse CD36 (85- kDa), a cell surface class B scavenger receptor. It blocks CD36 binding. It is not known whether the antibody is activating or neutralizing.
Kreuzreaktivität (Details) Species reactivity (tested):Mouse, rat
Endotoxin-Niveau Low Endotoxin
Klon CRF D2712
Isotyp IgA
Plasmids, Primers & others

Target Details CD36

Produktdetails anti-CD36 Antikörper Anwendungsinformationen Handhabung Referenzen für anti-CD36 Antikörper (ABIN1106326) Bilder zurück nach oben
Antigen
Andere Bezeichnung CD36 (CD36 Antibody Abstract)
Hintergrund Recently, CD36 has been identified as a protein that is required for TLR2 recognition of di-acylated bacterial lipopeptides and lipoteichoic acid. CD36 is a heavily N-glycosylated transmembrane protein with two short intracellular domains and a large extracellular domain. CD36 expression is primarily controlled by the transcription heterodimer PPARg-RXR (peroxisome proliferator-activated receptor-g-retinoid-X-receptor). CD36 is preferentially found within lipid rafts, which facilitates its association with receptors, signalling and adaptor molecules. CD36 is expressed on monocytes, macrophages, endothelial cells, hepatocytes, erythrocytes, adipocytes, cardiomyocytes and red skeletal muscle. Importantly it is expressed by steriodogenic cells in the adrenal gland, testis and ovary. CD36 has been implicated in many biological processes including angiogenesis, phagocytosis, inflammation, and lipid and glucose metabolism. CD36 is associated with Src-family kinases and with the integrins alpha3beta1 and alpha6beta1. It is a receptor and transporter of oxidized lipids and long chain fatty acids. CD36 has been shown to function as phagocytic receptor for apoptotic cells. Several in vivo models support the role of the thrombospondin / CD36 system in angiogenesis and tumor growth. An important role for CD36 has been found in Malaria as major receptor for P. falciparum-infected red blood cells. Many different ligands have been reported to interact with CD36, suggesting that CD36 could recognize a structure-based domain rather than specific contact residues.Synonyms: Fatty acid translocase, GP3B, GP4, Glycoprotein IIIb, PAS IV, PAS-4, Platelet collagen receptor, Platelet glycoprotein 4, Platelet glycoprotein IV, Thrombospondin receptor
Gen-ID 12491
NCBI Accession NP_001153027
UniProt Q08857
Pathways TLR Signalweg, Peptide Hormone Metabolism, Response to Growth Hormone Stimulus, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Regulation of Lipid Metabolism by PPARalpha, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Hepatitis C, Toll-Like Receptors Cascades, Lipid Metabolism

Anwendungsinformationen

Produktdetails anti-CD36 Antikörper Target Details CD36 Handhabung Referenzen für anti-CD36 Antikörper (ABIN1106326) Bilder zurück nach oben
Applikations-hinweise Optimal working dilution should be determined by the investigator.
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-CD36 Antikörper Target Details CD36 Anwendungsinformationen Referenzen für anti-CD36 Antikörper (ABIN1106326) Bilder zurück nach oben
Konzentration 0.1 mg/mL
Lagerung 4 °C
Informationen zur Lagerung Store at 2 - 8 °C.

Referenzen für anti-CD36 Antikörper (ABIN1106326)

Produktdetails anti-CD36 Antikörper Target Details CD36 Anwendungsinformationen Handhabung Bilder zurück nach oben
Allgemeine Veröffentlichungen

Bastie, Nahlé, McLoughlin, Esser, Zhang, Unterman, Abumrad: "FoxO1 stimulates fatty acid uptake and oxidation in muscle cells through CD36-dependent and -independent mechanisms." in: The Journal of biological chemistry, Vol. 280, Issue 14, pp. 14222-9, 2005

Gimeno, Ortegon, Patel, Punreddy, Ge, Sun, Lodish, Stahl: "Characterization of a heart-specific fatty acid transport protein." in: The Journal of biological chemistry, Vol. 278, Issue 18, pp. 16039-44, 2003

Corcoran, Vremec, Febbraio, Baldwin, Handman: "Differential regulation of CD36 expression in antigen-presenting cells: Oct-2 dependence in B lymphocytes but not dendritic cells or macrophages." in: International immunology, Vol. 14, Issue 10, pp. 1099-104, 2002

Smith, Serghides, Patel, Febbraio, Silverstein, Kain: "CD36-mediated nonopsonic phagocytosis of erythrocytes infected with stage I and IIA gametocytes of Plasmodium falciparum." in: Infection and immunity, Vol. 71, Issue 1, pp. 393-400, 2002

Kunjathoor, Febbraio, Podrez, Moore, Andersson, Koehn, Rhee, Silverstein, Hoff, Freeman: "Scavenger receptors class A-I/II and CD36 are the principal receptors responsible for the uptake of modified low density lipoprotein leading to lipid loading in macrophages." in: The Journal of biological chemistry, Vol. 277, Issue 51, pp. 49982-8, 2002