anti-Human CD36 Antikörper für Immunoprecipitation

Recommended CD36 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
CD36 Molecule (thrombospondin Receptor) (CD36) Antikörper
  • BDPLT10
  • CHDS7
  • FAT
  • GP3B
  • GP4
  • GPIV
  • PASIV
  • SCARB3
  • Fat
  • Scarb3
  • GPIIIB
  • PAS-4
  • zgc:92513
  • CD36 molecule
  • CD36 molecule (thrombospondin receptor)
  • CD36
  • Cd36
  • cd36
Reaktivität
Human
378
164
104
13
8
6
4
4
3
3
3
1
Wirt
Maus
262
154
48
12
2
Klonalität
Monoklonal
Konjugat
Dieser CD36 Antikörper ist konjugiert mit Biotin
52
27
21
21
13
9
8
6
5
5
5
3
3
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
Applikation
Functional Studies (Func), Flow Cytometry (FACS), Immunofluorescence (IF), Immunoprecipitation (IP)
294
165
135
102
64
46
44
41
39
28
14
3
3
3
3
3
3
2
2
2
2
1
1
1
1
Optionen
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Produktnummer ABIN2192000
$ 407.22
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
5.5 ABIN610057 FACS IP FITC Mouse IgM Anmelden zum Anzeigen SMO-SM0 3
5.5 ABIN610058 FACS IP Mouse IgM Anmelden zum Anzeigen SMO-SM0 3
4 ABIN2664613 IF IP WB Mouse IgG2a kappa Anmelden zum Anzeigen 5-271 4
1 ABIN610056 FACS IP Biotin Mouse IgM Anmelden zum Anzeigen SMO-SM0 0
1 ABIN610055 FACS IP Mouse IgM Anmelden zum Anzeigen SMO-SM0 0
1 ABIN211793 FACS IHC IHC (fro) IP WB Mouse IgM Anmelden zum Anzeigen SM0 0
1 ABIN203946 FACS IP Biotin Mouse IgM, kappa Anmelden zum Anzeigen 0
1 ABIN1106325 Func EIA IHC (fro) IF IP FITC Mouse IgG1 Anmelden zum Anzeigen FA6-152 5
1 ABIN203945 FACS IHC IHC (fro) IP Mouse IgM Anmelden zum Anzeigen 0
1 ABIN217796 FACS IHC IHC (fro) IP WB FITC Mouse IgM Anmelden zum Anzeigen 0
1 ABIN2225684 FACS IP FITC Mouse IgM Anmelden zum Anzeigen 7H216 0
1 ABIN2225682 FACS IP Mouse IgM Anmelden zum Anzeigen 7H216 0
1 ABIN2225683 FACS IP Biotin Mouse IgM kappa Anmelden zum Anzeigen 7H216 0
1 ABIN210200 FACS Func IHC IHC (fro) IP WB Mouse IgM Anmelden zum Anzeigen 0
1 ABIN2225681 FACS IP Mouse IgM Anmelden zum Anzeigen SMO 0
-8.341685 ABIN269593 Func IA ICC FACS IHC (fro) IF IP IHC WB Mouse IgG1 Anmelden zum Anzeigen FA6-152 5

General

Antigen CD36 Molecule (thrombospondin Receptor) (CD36) Antikörper
Reaktivität Human
(378), (164), (104), (13), (8), (6), (4), (4), (3), (3), (3), (1)
Wirt Maus
(262), (154), (48), (12), (2)
Klonalität (Klon)
Monoklonal   ( )
Konjugat Dieser CD36 Antikörper ist konjugiert mit Biotin
(52), (27), (21), (21), (13), (9), (8), (6), (5), (5), (5), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1)
Applikation Functional Studies (Func), Flow Cytometry (FACS), Immunofluorescence (IF), Immunoprecipitation (IP)
(294), (165), (135), (102), (64), (46), (44), (41), (39), (28), (14), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (1), (1), (1), (1)
Pubmed 1 Publikation vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-CD36 Antikörper

Target Details CD36 Anwendungsinformationen Handhabung Referenzen für anti-CD36 Antikörper (ABIN2192000) Bilder
Sterilität 0.2 μm filtered
Klon FA6-152
Plasmids, Primers & others

Target Details CD36

Produktdetails anti-CD36 Antikörper Anwendungsinformationen Handhabung Referenzen für anti-CD36 Antikörper (ABIN2192000) Bilder zurück nach oben
Antigen
Andere Bezeichnung CD36 (CD36 Antibody Abstract)
Hintergrund Monoclonal antibody FA6-152 recognizes human CD36 (88- kDa), a cell surface class B scavenger receptor, also known as thrombospondin receptor CD36 is a heavily N-glycosylated transmembrane protein of ~88 kDa with two short intracellular domains and a large extracellular domain. The protein is sensitive for neuroaminidase, resulting in a shift from 88 to 85 kDa. CD36 is expressed on platelets, mature monocytes and macrophages, microvascular endothelial cells, mammary endothelial cells, during stages of erythroid cell development and on some macrophage derived dendritic cells. The antibody recognizes adult and fetal monocytes, platelets and reticulocytes, but doesn't stain lymphocytes and granulocytes. Reactivity has also been found in small intestine, kidney, liver and thyroid. CD36 expression is primarily controlled by the transcription heterodimer PPARg-RXR (peroxisome proliferator-activated receptor-g-retinoid-X-receptor). CD36 is preferentially found within lipid rafts, which facilitates its association with receptors, signaling and adaptor molecules. It is a receptor and transporter of oxidized lipids and long chain fatty acids. CD36 has been implicated in many biological processes including angiogenesis, phagocytosis, inflammation, and lipid and glucose metabolism. Several in vivo models support the role of the thrombospondin / CD36 system in angiogenesis and tumor growth. An important role for CD36 has been found in Malaria as major receptor for P. falciparum-infected red blood cells. CD36 is associated with Src-family kinases and with the integrins α3β1 and α6β1. Recently, CD36 has been identified as a protein that is required for toll like receptor (TLR2) recognition of di-acylated bacterial lipopeptides and lipoteichoic acid4. Furthermore, CD36 has been shown to function as phagocytic receptor for apoptotic cells. Many different ligands have been reported to interact with CD36, suggesting that CD36 could recognize a structure-based domain rather than specific contact residues. Monoclonal antibody FA6-152 blocks the biological activity of CD36 by blocking collagen/thrombospondin binding. The antibody agglutinates fetal but not adult erythrocytes. Aliases GPIV, FAT, platelet glycoprotein 4, thrombospondin receptor Immunogen 20-Weeks-old fetal erythrocytes
Pathways TLR Signalweg, Peptide Hormone Metabolism, Response to Growth Hormone Stimulus, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Regulation of Lipid Metabolism by PPARalpha, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Hepatitis C, Toll-Like Receptors Cascades, Lipid Metabolism

Anwendungsinformationen

Produktdetails anti-CD36 Antikörper Target Details CD36 Handhabung Referenzen für anti-CD36 Antikörper (ABIN2192000) Bilder zurück nach oben
Applikations-hinweise For immunohistology and flow cytometry, dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:50. For functional studies, in vitro dilutions have to be optimized in user's experimental setting. Positive HEL cells control
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Handhabung

Produktdetails anti-CD36 Antikörper Target Details CD36 Anwendungsinformationen Referenzen für anti-CD36 Antikörper (ABIN2192000) Bilder zurück nach oben
Buffer PBS, containing 0.1 % bovine serum albumin and 0.02 % sodium azide.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung 4 °C
Informationen zur Lagerung Product should be stored at 4 °C. Under recommended storage conditions, product is stable for at least one year. The exact expiry date is indicated on the label.

Referenzen für anti-CD36 Antikörper (ABIN2192000)

Produktdetails anti-CD36 Antikörper Target Details CD36 Anwendungsinformationen Handhabung Bilder zurück nach oben
Allgemeine Veröffentlichungen

Edelman, Vinci, Villeval, Vainchenker, Henri, Miglierina, Rouger, Reviron, Breton-Gorius, Sureau: "A monoclonal antibody against an erythrocyte ontogenic antigen identifies fetal and adult erythroid progenitors." in: Blood, Vol. 67, Issue 1, pp. 56-63, 1986