Transforming Growth Factor, beta 2 Produkte
(Transforming Growth Factor, beta 2 (TGFB2))
Kategorien
This gene encodes a member of the transforming growth factor beta (TGFB) family of cytokines, which are multifunctional peptides that regulate proliferation, differentiation, adhesion, migration, and other functions in many cell types by transducing their signal through combinations of transmembrane type I and type II receptors (TGFBR1 and TGFBR2) and their downstream effectors, the SMAD proteins. Disruption of the TGFB/SMAD pathway has been implicated in a variety of human cancers. The encoded protein is secreted and has suppressive effects of interleukin-2 dependent T-cell growth. Translocation t(1\;7)(q41\;p21) between this gene and HDAC9 is associated with Peters' anomaly, a congenital defect of the anterior chamber of the eye. The knockout mice lacking this gene show perinatal mortality and a wide range of developmental, including cardiac, defects. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Sep 2010].
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Ausgewählte Transforming Growth Factor, beta 2 Kategorien
Transforming Growth Factor, beta 2 Antikörper
High quality antibodies with extensive validation data.
Transforming Growth Factor, beta 2 ELISA Kits
Reliable ELISA kits for a wide range of species.
Transforming Growth Factor, beta 2 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene Transforming Growth Factor, beta 2 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IHC, IF
Validierungen
- (6)
Kat. Nr.
ABIN3029221
Menge
0.4 mL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, IP, ICC
Validierungen
- (4)
Kat. Nr.
ABIN7429457
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Rat
Applikation
WB, IHC, IP, ICC
Validierungen
- (4)
Kat. Nr.
ABIN7429460
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene Transforming Growth Factor, beta 2 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Competition ELISA
Validierungen
- (1)
- (1)
Kat. Nr.
ABIN6960089
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
- (1)
Kat. Nr.
ABIN6960093
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Rat
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6960096
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene Transforming Growth Factor, beta 2 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Tobacco (Nicotiana benthamiana)
Validierungen
- (4)
- (2)
Kat. Nr.
ABIN1112028
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
HEK-293 Cells
Validierungen
- (2)
Kat. Nr.
ABIN7275710
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
HEK-293 Cells
Validierungen
- (2)
Kat. Nr.
ABIN7275711
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren Transforming Growth Factor, beta 2 Produkten
: "Crystallins Play a Crucial Role in Glaucoma and Promote Neuronal Cell Survival in an In Vitro Model Through Modulating Müller Cell Secretion." in: Investigative ophthalmology & visual science, Vol. 63, Issue 8, pp. 3, (2022) (PubMed).: "Angiocrine signals regulate quiescence and therapy resistance in bone metastasis." in: JCI insight, Vol. 4, Issue 13, (2020) (PubMed).
: "GFI1 downregulation promotes inflammation-linked metastasis of colorectal cancer." in: Cell death and differentiation, Vol. 24, Issue 5, pp. 929-943, (2018) (PubMed).
: "A microfluidic device for studying chemotaxis mechanism of bacterial cancer targeting." in: Scientific reports, Vol. 8, Issue 1, pp. 6394, (2018) (PubMed).
: "Plasminogen Activator Inhibitor-1 Protects Mice Against Cardiac Fibrosis by Inhibiting Urokinase-type Plasminogen Activator-mediated Plasminogen Activation." in: Scientific reports, Vol. 7, Issue 1, pp. 365, (2017) (PubMed).
: "Effects of ranibizumab on TGF-β1 and TGF-β2 production by human Tenon's fibroblasts: An in vitro study." in: Molecular vision, Vol. 21, pp. 1191-200, (2016) (PubMed).
: "SP600125 promotes resolution of allergic airway inflammation via TLR9 in an OVA-induced murine acute asthma model." in: Molecular immunology, (2015) (PubMed).
: "Influence of the Expression Level of O6-Alkylguanine-DNA Alkyltransferase on the Formation of DNA Interstrand Crosslinks Induced by Chloroethylnitrosoureas in Cells: A Quantitation Using ..." in: PLoS ONE, Vol. 10, Issue 3, pp. e0121225, (2015) (PubMed).
: "MicroRNA-26a modulates transforming growth factor beta-1-induced proliferation in human fetal lung fibroblasts." in: Biochemical and biophysical research communications, Vol. 454, Issue 4, pp. 512-517, (2014) (PubMed).
: "Elevated PLGF contributes to small-cell lung cancer brain metastasis." in: Oncogene, Vol. 32, Issue 24, pp. 2952-62, (2013) (PubMed).
Synonyme und alternative Namen zu Transforming Growth Factor, beta 2
transforming growth factor beta 2 (TGFB2), transforming growth factor beta 2 L homeolog (tgfb2.L), transforming growth factor, beta 2 (Tgfb2), transforming growth factor, beta receptor 2 (Tgfbr2), transforming growth factor, beta 2 (tgfb2), transforming growth factor beta 2 (Tgfb2), BB105277, LDS4, MGF, TGF-B2, TGF-beta2, tgf-beta2, Tgf-beta2, TGF-beta 2, Tgfb-2, TGFB2, tgfb2-A, TGFbeta2, Tgfbr2TBezeichner auf Proteinebene für Transforming Growth Factor, beta 2
- BSC-1 cell growth inhibitor
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- glioblastoma-derived T-cell suppressor factor
- polyergin
- transforming growth factor beta-2
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- TGF-beta receptor type II
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- transforming growth factor beta receptor type II
- transforming growth factor beta, receptor 2
- transforming growth factor, beta receptor 2
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- transforming growth factor-b type II receptor
- transforming growth factor-beta receptor type II
- transforming growth factor-beta type II receptor
- tgf beta 2
- transforming growth factor, beta 2
- milk growth factor
- transforming growth factor-beta 2
- transforming growth factor beta-2-like
- TGF beta 2 protein
- transforming growth factor-beta2
- TGF beta 2
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