anti-Human RFC2 Antikörper für Enzyme Immunoassay

Recommended RFC2 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Replication Factor C (Activator 1) 2, 40kDa (RFC2) Antikörper
  • 2610008M13Rik
  • 40kDa
  • AI326953
  • Recc2
  • RFC40
  • replication factor C subunit 2
  • replication factor C (activator 1) 2
  • LOC100231971
  • RFC2
  • Rfc2
Epitop
N-Term
15
12
6
5
4
3
3
2
2
2
2
1
1
1
1
1
1
Reaktivität
Human
78
41
39
7
4
4
4
3
3
3
1
1
Wirt
Kaninchen
57
20
1
Klonalität
Polyklonal
Konjugat
Dieser RFC2 Antikörper ist unkonjugiert
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Applikation
Enzyme Immunoassay (EIA), Western Blotting (WB)
63
18
16
13
13
11
7
2
Optionen
Hersteller
Anmelden zum Anzeigen
Hersteller Produkt- Nr.
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Bilder

Produktnummer ABIN357963
$ 484.00
Zzgl. Versandkosten $45.00

General

Antigen Replication Factor C (Activator 1) 2, 40kDa (RFC2) Antikörper
Epitop N-Term
(15), (12), (6), (5), (4), (3), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1)
Reaktivität Human
(78), (41), (39), (7), (4), (4), (4), (3), (3), (3), (1), (1)
Wirt Kaninchen
(57), (20), (1)
Klonalität
Polyklonal
Konjugat Dieser RFC2 Antikörper ist unkonjugiert
(1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Applikation Enzyme Immunoassay (EIA), Western Blotting (WB)
(63), (18), (16), (13), (13), (11), (7), (2)
Pubmed 2 Publikationen vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-RFC2 Antikörper

Target Details RFC2 Anwendungsinformationen Handhabung Referenzen für anti-RFC2 Antikörper (ABIN357963) Bilder
Spezifität This antibody detects RFC2 (N-term).
Reinigung Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Immunogen This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human RFC2.
Isotyp Ig Fraction
Plasmids, Primers & others

Target Details RFC2

Produktdetails anti-RFC2 Antikörper Anwendungsinformationen Handhabung Referenzen für anti-RFC2 Antikörper (ABIN357963) Bilder zurück nach oben
Antigen
Andere Bezeichnung RFC2 / RFC40 (RFC2 Antibody Abstract)
Hintergrund The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins, proliferating cell nuclear antigen (PCNA) and replication factor C (RFC). RFC, also called activator 1, is a protein complex consisting of five distinct subunits of 145, 40, 38, 37, and 36.5 kD. RFC2 is the 40 kD subunit, which has been shown to be responsible for binding ATP. Deletion of RFC2 gene has been associated with Williams syndrome.Synonyms: Activator 1 40 kDa subunit, Activator 1 subunit 2, RF-C 40 kDa subunit, Replication factor C 40 kDa subunit, Replication factor C subunit 2
Molekulargewicht 39157 Da
Gen-ID 5982, 9606
UniProt P35250
Pathways Telomere Maintenance, DNA Reparatur, DNA Replication, Synthesis of DNA

Anwendungsinformationen

Produktdetails anti-RFC2 Antikörper Target Details RFC2 Handhabung Referenzen für anti-RFC2 Antikörper (ABIN357963) Bilder zurück nach oben
Applikations-hinweise ELISA: 1/1,000. Western Blot: 1/50-1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-RFC2 Antikörper Target Details RFC2 Anwendungsinformationen Referenzen für anti-RFC2 Antikörper (ABIN357963) Bilder zurück nach oben
Format Liquid
Konzentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) Sodium Azide as preservative.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freezing and thawing.
Lagerung 4 °C/-20 °C
Informationen zur Lagerung Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Referenzen für anti-RFC2 Antikörper (ABIN357963)

Produktdetails anti-RFC2 Antikörper Target Details RFC2 Anwendungsinformationen Handhabung Bilder zurück nach oben
Allgemeine Veröffentlichungen

Tomida, Masuda, Hiroaki, Ishikawa, Song, Tsurimoto, Tateishi, Shiomi, Kamei, Kim, Kamiya, Vaziri, Ohmori, Todo: "DNA damage-induced ubiquitylation of RFC2 subunit of replication factor C complex." in: The Journal of biological chemistry, Vol. 283, Issue 14, pp. 9071-9, 2008

Gupte, Weng, Liu, Lee: "The second subunit of the replication factor C complex (RFC40) and the regulatory subunit (RIalpha) of protein kinase A form a protein complex promoting cell survival." in: Cell cycle (Georgetown, Tex.), Vol. 4, Issue 2, pp. 323-9, 2005

Bilder

Produktdetails anti-RFC2 Antikörper Target Details RFC2 Anwendungsinformationen Handhabung Referenzen für anti-RFC2 Antikörper (ABIN357963) zurück nach oben
Bilder des Herstellers
 image for anti-Replication Factor C (Activator 1) 2, 40kDa (RFC2) (N-Term) antibody (ABIN357963) anti-Replication Factor C (Activator 1) 2, 40kDa (RFC2) (N-Term) antibody