anti-Maus CD80 Antikörper für Immunofluorescence

Recommended CD80 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
CD80 Antikörper
  • B7
  • B7-1
  • B7.1
  • BB1
  • CD28LG
  • CD28LG1
  • LAB7
  • B71
  • Cd28l
  • Ly-53
  • Ly53
  • MIC17
  • TSA1
  • CD80 molecule
  • Cd80 molecule
  • CD80 antigen
  • CD80
  • Cd80
Reaktivität
Maus
496
293
49
11
11
6
3
3
3
2
1
1
Wirt
Hamster
440
126
100
93
46
17
Klonalität
Monoklonal
Konjugat
Dieser CD80 Antikörper ist konjugiert mit Pacific Blue
76
75
56
44
21
19
19
17
10
9
9
7
7
7
7
7
7
6
6
6
6
6
5
4
4
4
4
4
3
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Applikation
Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (IHC)
554
223
172
157
119
99
81
43
41
26
23
21
13
8
8
6
6
5
5
5
4
2
2
2
2
1
1
1
Hersteller
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Bilder

Produktnummer ABIN2662310
Preis und Verfügbarkeit auf Anfrage.
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
1 ABIN2657475 ICC IF IP IHC ELISA WB Alexa Fluor 488 Hamster IgG Anmelden zum Anzeigen 16-10A1 11
1 ABIN2662311 FACS IF IHC Pacific Blue Hamster IgG Anmelden zum Anzeigen 16-10A1 11
1 ABIN2657476 ICC IF IP IHC ELISA WB Alexa Fluor 488 Hamster IgG Anmelden zum Anzeigen 16-10A1 11
1 ABIN4903203 FACS IF IHC WB Mouse IgG Anmelden zum Anzeigen 0
1 ABIN2567925 Func FACS IF IP IHC Hamster IgG Anmelden zum Anzeigen 16-10A1 0

General

Antigen CD80 Antikörper
Reaktivität Maus
(496), (293), (49), (11), (11), (6), (3), (3), (3), (2), (1), (1)
Wirt Hamster
(440), (126), (100), (93), (46), (17)
Klonalität (Klon)
Monoklonal   ( )
Konjugat Dieser CD80 Antikörper ist konjugiert mit Pacific Blue
(76), (75), (56), (44), (21), (19), (19), (17), (10), (9), (9), (7), (7), (7), (7), (7), (7), (6), (6), (6), (6), (6), (5), (4), (4), (4), (4), (4), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Applikation Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (IHC)
(554), (223), (172), (157), (119), (99), (81), (43), (41), (26), (23), (21), (13), (8), (8), (6), (6), (5), (5), (5), (4), (2), (2), (2), (2), (1), (1), (1)
Pubmed 11 Publikationen vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-CD80 Antikörper

Target Details CD80 Anwendungsinformationen Handhabung Referenzen für anti-CD80 Antikörper (ABIN2662310) Bilder
Kreuzreaktivität Hund
Reinigung The antibody was purified by affinity chromatography, and conjugated with Pacific Blue™ under optimal conditions. The solution is free of unconjugated Pacific Blue™.
Klon 16-10A1
Isotyp IgG
Plasmids, Primers & others

Target Details CD80

Produktdetails anti-CD80 Antikörper Anwendungsinformationen Handhabung Referenzen für anti-CD80 Antikörper (ABIN2662310) Bilder zurück nach oben
Antigen
Andere Bezeichnung CD80 (CD80 Antibody Abstract)
Hintergrund CD80 is a 60 kD highly glycosylated protein. It is a member of the Ig superfamily and is also known as B7-1, B7, and Ly-53. CD80 is constitutively expressed on dendritic cells and monocytes/macrophages, and inducibly expressed on activated B and T cells. The ligation of CD28 on T cells with CD80 and CD86 (B7-2) on antigen presenting cells (such as dendritic cells, macrophages, and B cells) elicits co-stimulation of T cells resulting in enhanced cell activation, proliferation, and cytokine production. CD80 appears to be expressed later in the immune response than CD86. CD80 can also bind to CD152, also known as CTLA-4, to deliver an inhibitory signal to T cells.
Pathways T-Zell Rezeptor Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Positive Regulation of Immune Effector Process

Anwendungsinformationen

Produktdetails anti-CD80 Antikörper Target Details CD80 Handhabung Referenzen für anti-CD80 Antikörper (ABIN2662310) Bilder zurück nach oben
Applikations-hinweise Optimal working dilution should be determined by the investigator.
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-CD80 Antikörper Target Details CD80 Anwendungsinformationen Referenzen für anti-CD80 Antikörper (ABIN2662310) Bilder zurück nach oben
Konzentration 0.5 mg/mL
Buffer Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Protect from prolonged exposure to light. Do not freeze.
Lagerung 4 °C
Informationen zur Lagerung The antibody solution should be stored undiluted between 2°C and 8°C.

Referenzen für anti-CD80 Antikörper (ABIN2662310)

Produktdetails anti-CD80 Antikörper Target Details CD80 Anwendungsinformationen Handhabung Bilder zurück nach oben
Allgemeine Veröffentlichungen

Misra, Shi, Moreno-Garcia, Thankappan, Tighe, Mousseau, Kusser, Becker-Herman, Hudkins, Dunn, Kehry, Migone, Marshak-Rothstein, Simon, Randall, Alpers, Liggitt, Rawlings, Lund: "G alpha q-containing G proteins regulate B cell selection and survival and are required to prevent B cell-dependent autoimmunity." in: The Journal of experimental medicine, Vol. 207, Issue 8, pp. 1775-89, 2010

Lawson, Manenkova, Ahamed, Chen, Zou, Baccala, Theofilopoulos, Yuan: "Inhibition of transmethylation down-regulates CD4 T cell activation and curtails development of autoimmunity in a model system." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 178, Issue 8, pp. 5366-74, 2007

Turnquist, Raimondi, Zahorchak, Fischer, Wang, Thomson: "Rapamycin-conditioned dendritic cells are poor stimulators of allogeneic CD4+ T cells, but enrich for antigen-specific Foxp3+ T regulatory cells and promote organ transplant tolerance." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 178, Issue 11, pp. 7018-31, 2007

Ma, Xu, An, Dong, Lin, Shi, Wu: "Vaccine with beta-defensin 2-transduced leukemic cells activates innate and adaptive immunity to elicit potent antileukemia responses." in: Cancer research, Vol. 66, Issue 2, pp. 1169-76, 2006

Andoniou, van Dommelen, Voigt, Andrews, Brizard, Asselin-Paturel, Delale, Stacey, Trinchieri, Degli-Esposti: "Interaction between conventional dendritic cells and natural killer cells is integral to the activation of effective antiviral immunity." in: Nature immunology, Vol. 6, Issue 10, pp. 1011-9, 2005

Salomon, Bluestone: "Complexities of CD28/B7: CTLA-4 costimulatory pathways in autoimmunity and transplantation." in: Annual review of immunology, Vol. 19, pp. 225-52, 2001

Herold, Vezys, Koons, Lenschow, Thompson, Bluestone: "CD28/B7 costimulation regulates autoimmune diabetes induced with multiple low doses of streptozotocin." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 158, Issue 2, pp. 984-91, 1997

Harlan, Hengartner, Huang, Kang, Abe, Moreadith, Pircher, Gray, Ohashi, Freeman: "Mice expressing both B7-1 and viral glycoprotein on pancreatic beta cells along with glycoprotein-specific transgenic T cells develop diabetes due to a breakdown of T-lymphocyte unresponsiveness." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 91, Issue 8, pp. 3137-41, 1994

Hathcock, Laszlo, Pucillo, Linsley, Hodes: "Comparative analysis of B7-1 and B7-2 costimulatory ligands: expression and function." in: The Journal of experimental medicine, Vol. 180, Issue 2, pp. 631-40, 1994

Razi-Wolf, Freeman, Galvin, Benacerraf, Nadler, Reiser: "Expression and function of the murine B7 antigen, the major costimulatory molecule expressed by peritoneal exudate cells." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 89, Issue 9, pp. 4210-4, 1992

Linsley, Brady, Urnes, Grosmaire, Damle, Ledbetter: "CTLA-4 is a second receptor for the B cell activation antigen B7." in: The Journal of experimental medicine, Vol. 174, Issue 3, pp. 561-9, 1991

Bilder

Produktdetails anti-CD80 Antikörper Target Details CD80 Anwendungsinformationen Handhabung Referenzen für anti-CD80 Antikörper (ABIN2662310) zurück nach oben
Bilder des Herstellers
Flow Cytometry (FACS) image for anti-CD80 (CD80) antibody (Pacific Blue) (ABIN2662310) anti-CD80 (CD80) antibody (Pacific Blue)