anti-Ratte (Rattus) Synaptotagmin III Antikörper für Immunocytochemistry

Recommended Synaptotagmin III Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Synaptotagmin III (SYT3) Antikörper
  • SytIII
  • AI385753
  • sytIII
  • SIII
  • synaptotagmin 3
  • synaptotagmin III
  • SYT3
  • Syt3
Epitop
AA 442-533
53
10
6
5
2
2
1
1
1
1
Reaktivität
Human, Maus, Ratte (Rattus)
103
92
85
3
2
2
2
2
2
1
1
Wirt
Maus
63
38
11
Klonalität
Monoklonal
Konjugat
Atto 390
7
7
6
5
5
4
4
4
3
3
3
3
3
3
3
2
2
1
1
1
1
1
1
1
1
1
1
1
1
Applikation
Immunocytochemistry (ICC), Immunofluorescence (IF), Western Blotting (WB)
86
45
26
23
18
13
10
4
3
2
2
2
1
Optionen
Hersteller
Anmelden zum Anzeigen
Hersteller Produkt- Nr.
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Bilder

Produktnummer ABIN2483631
$ 516.10
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
18.572235 ABIN2483633 ICC IF WB Atto 565 Mouse IgG1 AA 442-533 Anmelden zum Anzeigen S278-19 0
18.572235 ABIN2483634 ICC IF WB Atto 594 Mouse IgG1 AA 442-533 Anmelden zum Anzeigen S278-19 0
18.572235 ABIN2483635 ICC IF WB Atto 633 Mouse IgG1 AA 442-533 Anmelden zum Anzeigen S278-19 0
18.572235 ABIN2483639 ICC IF WB Alkaline Phosphatase (AP) Mouse IgG1 AA 442-533 Anmelden zum Anzeigen S278-19 0
18.572235 ABIN2483640 ICC IF WB APC Mouse IgG1 AA 442-533 Anmelden zum Anzeigen S278-19 0
18.572235 ABIN2483638 ICC IF WB Atto 700 Mouse IgG1 AA 442-533 Anmelden zum Anzeigen S278-19 0
18.572235 ABIN2483642 ICC IF WB FITC Mouse IgG1 AA 442-533 Anmelden zum Anzeigen S278-19 0
18.572235 ABIN2483643 ICC IF WB HRP Mouse IgG1 AA 442-533 Anmelden zum Anzeigen S278-19 0
18.572235 ABIN2483646 ICC IF WB PE Mouse IgG1 AA 442-533 Anmelden zum Anzeigen S278-19 0
18.572235 ABIN2483645 ICC IF WB PerCP Mouse IgG1 AA 442-533 Anmelden zum Anzeigen S278-19 0
18.572235 ABIN2483644 ICC IF WB PE-Atto 594 Mouse IgG1 AA 442-533 Anmelden zum Anzeigen S278-19 0
18.572235 ABIN2483647 ICC IF WB Streptavidin Mouse IgG1 AA 442-533 Anmelden zum Anzeigen S278-19 0
18.572235 ABIN2483641 ICC IF WB Biotin Mouse IgG1 AA 442-533 Anmelden zum Anzeigen S278-19 0
18.572235 ABIN2483632 ICC IF WB Atto 488 Mouse IgG1 AA 442-533 Anmelden zum Anzeigen S278-19 0
18.572235 ABIN2483637 ICC IF WB Atto 680 Mouse IgG1 AA 442-533 Anmelden zum Anzeigen S278-19 0
18.572235 ABIN2483636 ICC IF WB Atto 655 Mouse IgG1 AA 442-533 Anmelden zum Anzeigen S278-19 0
18.572235 ABIN1686635 ICC IF WB Mouse IgG1 AA 442-533 Anmelden zum Anzeigen S278-19 0
14.054465 ABIN1742204 ICC Rabbit AA 180-293 Anmelden zum Anzeigen Polyclonal 0
1 ABIN1939907 ICC WB Atto 565 Mouse IgG1 AA 442-533 Anmelden zum Anzeigen S278-19 0
1 ABIN1939911 ICC WB Atto 680 Mouse IgG1 AA 442-533 Anmelden zum Anzeigen S278-19 0

General

Antigen Synaptotagmin III (SYT3) Antikörper
Epitop AA 442-533
(53), (10), (6), (5), (2), (2), (1), (1), (1), (1)
Reaktivität Human, Maus, Ratte (Rattus)
(103), (92), (85), (3), (2), (2), (2), (2), (2), (1), (1)
Wirt Maus
(63), (38), (11)
Klonalität (Klon)
Monoklonal   ( )
Konjugat Atto 390
(7), (7), (6), (5), (5), (4), (4), (4), (3), (3), (3), (3), (3), (3), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Applikation Immunocytochemistry (ICC), Immunofluorescence (IF), Western Blotting (WB)
(86), (45), (26), (23), (18), (13), (10), (4), (3), (2), (2), (2), (1)
Hersteller Anmelden zum Anzeigen

Produktdetails

Antigendetails Anwendungsinformationen Handhabung Bilder
Spezifität Detects ~75 kDa. Does not cross-react with other Synaptotagmins.
Reinigung Protein G Purified
Immunogen Fusion protein amino acids 442-533 (Cytoplasmic C2B domain) of mouse Synaptotagmin-3
Klon S278-19
Isotyp IgG1

Antigendetails

Produktdetails Anwendungsinformationen Handhabung Bilder zurück nach oben
Antigen
Andere Bezeichnung Synaptotagmin 3 (SYT3 Antibody Abstract)
Hintergrund Synaptotagmins constitute a family of membrane-trafficking proteins that are characterized by an N-terminal transmembrane region (TMR), a variable linker, and two C-terminal C2 domains - C2A and C2B. There are 15 members in the mammalian synaptotagmin family. There are several C2-domain containing protein families that are related to synaptotagmins, including transmembrane (Ferlins, E-Syts, and MCTPs) and soluble (RIMs, Munc13s, synaptotagmin-related proteins and B/K) proteins. The synaptotagmins are integral membrane proteins of synaptic vesicles thought to serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis. Calcium binding to synaptotagmin participates in triggering neurotransmitter release at the synapse. The first domain mediates Ca(2+)-dependent phospholipid binding. The second C2 domain mediates interaction with Stonin 2. Synaptotagmin may have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacylbackbone. A Ca(2+)-dependent interaction between synaptotagmin and putative receptors for activated protein kinase C has also been reported. It can bind to at least three additional proteins in a Ca(2+)-independent manner, these are neurexins, syntaxin and AP2.
Gen-ID 20981
NCBI Accession NP_001107588
UniProt O35681
Pathways Synaptic Vesicle Exocytosis

Anwendungsinformationen

Produktdetails Antigendetails Handhabung Bilder zurück nach oben
Applikations-hinweise
  • WB (1:1000)
  • optimal dilutions for assays should be determined by the user.
Kommentare

1 μg/ml of SMC-426 was sufficient for detection of Synaptotagmin-3 in 20 μg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.

Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails Antigendetails Anwendungsinformationen Bilder zurück nach oben
Format Liquid
Konzentration 1 mg/mL
Buffer PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C

Bilder

Produktdetails Antigendetails Anwendungsinformationen Handhabung zurück nach oben
Bilder des Herstellers
Immunofluorescence (fixed cells) (IF/ICC) image for anti-Synaptotagmin III (SYT3) (AA 442-533) antibody (Atto 390) (ABIN2483631) Immunocytochemistry/Immunofluorescence analysis using Mouse Anti-Synaptotagmin-3 Mono...
Western Blotting (WB) image for anti-Synaptotagmin III (SYT3) (AA 442-533) antibody (Atto 390) (ABIN2483631) Western Blot analysis of Rat Brain Membrane showing detection of ~75 kDa Synaptotagmi...