Ziege anti-Ratte IgG Antikörper (FITC)

Produktnummer ABIN2176441

Produktdetails

Target: IgG

Reaktivität: Ratte

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: FITC

Applikation: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Aufreinigung: Purified by Protein A.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P): (1:500-2000), IF(IHC-F): (1:500-2000), IF(ICC): (1:500-1000)
Optimal working dilution should be determined by the investigator.

Kommentare:

Exitation/Emission: 494nm/518nm

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 100 μg/mL BSA, 50 % glycerol and 0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at 4 °C for 12 months.

Referenzen

Zhou, Sun: "Edwardsiella tarda-Induced Inhibition of Apoptosis: A Strategy for Intracellular Survival." in: Frontiers in cellular and infection microbiology, Vol. 6, pp. 76, (2017) (PubMed).

Zhang, Li: "ORF75 of megalocytivirus RBIV-C1: A global transcription regulator and an effective vaccine candidate." in: Fish & shellfish immunology, Vol. 45, Issue 2, pp. 486-94, (2015) (PubMed).

Zhong, Li, Zhu, Guan, Yang, Zhou, Zhang, Huang: "A smart polymeric platform for multistage nucleus-targeted anticancer drug delivery." in: Biomaterials, Vol. 65, pp. 43-55, (2015) (PubMed).

Zhang, Sun et al.: "Tongue sole (Cynoglossus semilaevis) prothymosin alpha: Cytokine-like activities associated with the intact protein and the C-terminal region that lead to antiviral immunity via Myd88-dependent and ..." in: Developmental and comparative immunology, Vol. 53, Issue 1, pp. 96-104, (2015) (PubMed).

Yan, Zhao, Wu, Liu, Wu, Li, Zheng, Jiang: "Inflammation and pathological damage to the lungs of mice are only partially reversed following smoking cessation on subacute exposure to cigarette smoke." in: Molecular medicine reports, Vol. 11, Issue 6, pp. 4246-54, (2015) (PubMed).

Li, Zhang, Li, Sun: "Sil: a Streptococcus iniae bacteriocin with dual role as an antimicrobial and an immunomodulator that inhibits innate immune response and promotes S. iniae infection." in: PLoS ONE, Vol. 9, Issue 4, pp. e96222, (2014) (PubMed).

Zhang, Zhang, Sun: "Junctional adhesion molecule A of red drum (Sciaenops ocellatus): a possible immunomodulator and a target for bacterial immune evasion." in: Veterinary immunology and immunopathology, Vol. 161, Issue 1-2, pp. 99-107, (2014) (PubMed).

Qiu, Sun, Li, Liu, Sun et al.: "Identification and characterization of a cell surface scavenger receptor cysteine-rich protein of Sciaenops ocellatus: bacterial interaction and its dependence on the conserved structural features of ..." in: Fish & shellfish immunology, Vol. 34, Issue 3, pp. 810-8, (2013) (PubMed).

Cheng, Hu, Sun, Zhang, Chi, Sun: "A single immunoglobulin-domain IgSF protein from Sciaenops ocellatus regulates pathogen-induced immune response in a negative manner." in: Developmental and comparative immunology, Vol. 38, Issue 1, pp. 117-27, (2012) (PubMed).

Antigendetails

Target: IgG

Abstract: IgG Produkte

Substanzklasse: Antibody

Hintergrund: Immunoglobulin G (IgG), is one of the most abundant proteins in serum with normal levels between 8-17 mg/mL in adult blood. IgG is important for our defence against microorganisms and the molecules are produced by B lymphocytes as a part of our adaptive immune response. The IgG molecule has two separate functions, to bind to the pathogen that elicited the response and to recruit other cells and molecules to destroy the antigen. The variability of the IgG pool is generated by somatic recombination and the number of specificities in an individual at a given time point is estimated to be 1011 variants.