anti-Ratte (Rattus) Ret Proto-Oncogene Antikörper für ELISA

Recommended Ret Proto-Oncogene Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Ret Proto-Oncogene (RET) Antikörper
  • c-ret
  • cret
  • etID315074.13
  • ret1
  • wu:fd13h01
  • X-ret
  • ret-A
  • xret
  • RET
  • MTC1
  • CDHF12
  • CDHR16
  • HSCR1
  • MEN2A
  • MEN2B
  • PTC
  • RET-ELE1
  • RET51
  • RET9
  • c-Ret
  • ret proto-oncogene receptor tyrosine kinase
  • ret proto-oncogene S homeolog
  • ret proto-oncogene
  • ret
  • ret.S
  • RET
  • Ret
Epitop
pTyr1096
49
42
26
26
26
22
18
15
14
11
11
8
7
7
7
7
7
7
7
6
5
5
4
4
3
3
3
3
3
3
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
Reaktivität
Human, Maus, Ratte (Rattus)
362
128
118
9
3
2
2
2
2
1
1
1
1
1
1
1
Wirt
Kaninchen
256
104
5
2
1
1
Klonalität
Polyklonal
Konjugat
Dieser Ret Proto-Oncogene Antikörper ist unkonjugiert
16
14
14
12
9
9
6
6
6
6
6
5
5
5
5
5
5
1
1
1
1
1
Applikation
ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting (WB)
270
155
122
67
65
39
34
12
7
6
6
3
3
1
1
Hersteller
Anmelden zum Anzeigen
Hersteller Produkt- Nr.
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Bilder

Produktnummer ABIN6271278
$ 450.00
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
16 ABIN6271568 ELISA ICC IF IHC WB Rabbit IgG pTyr1015 Anmelden zum Anzeigen Polyclonal 0
15.755764 ABIN3186735 ELISA WB Rabbit IgG Thr788 Anmelden zum Anzeigen Polyclonal 0
15.755764 ABIN3186734 ELISA IF IHC WB Rabbit IgG Thr77 Anmelden zum Anzeigen Polyclonal 0
12.755764 ABIN3182407 ELISA IHC WB Rabbit IgG pTyr1062 Anmelden zum Anzeigen Polyclonal 0
12.755764 ABIN3182216 ELISA WB Rabbit IgG pTyr1015 Anmelden zum Anzeigen Polyclonal 0
12.755764 ABIN3183018 ELISA IF IHC Rabbit IgG pTyr905 Anmelden zum Anzeigen Polyclonal 0
12.755764 ABIN2150513 ELISA WB Rabbit IgG pTyr1062 Anmelden zum Anzeigen Polyclonal 0
10 ABIN6256615 ELISA ICC IF WB Rabbit IgG pTyr1062 Anmelden zum Anzeigen Polyclonal 0
10 ABIN6264702 ELISA ICC IF WB Rabbit IgG Anmelden zum Anzeigen Polyclonal 0
7 ABIN6271276 ELISA ICC IF WB Rabbit IgG pTyr905 Anmelden zum Anzeigen Polyclonal 0
4 ABIN1531387 ELISA WB Rabbit IgG AA 991-1040, pTyr1015 Anmelden zum Anzeigen Polyclonal 2
4 ABIN1531965 ELISA WB Rabbit IgG AA 1041-1090, pTyr1062 Anmelden zum Anzeigen Polyclonal 0
4 ABIN1532999 ELISA WB Rabbit IgG AA 1041-1090 Anmelden zum Anzeigen Polyclonal 0
4 ABIN2888523 ELISA WB Rabbit IgG pTyr1062 Anmelden zum Anzeigen Polyclonal 0
4 ABIN2889062 ELISA WB Rabbit IgG AA 1041-1090 Anmelden zum Anzeigen Polyclonal 0
4 ABIN5959836 ELISA IF IHC (p) WB Rabbit IgG Tyr905 Anmelden zum Anzeigen Polyclonal 0
4 ABIN5959837 ELISA WB Rabbit IgG Tyr1062 Anmelden zum Anzeigen Polyclonal 0
1 ABIN1450578 IF IHC ELISA WB Rabbit IgG AA 881-930 Anmelden zum Anzeigen Polyclonal 2
1 ABIN1450308 IF IHC ELISA Rabbit IgG AA 881-930, pTyr905 Anmelden zum Anzeigen Polyclonal 0
1 ABIN2884297 ELISA IF IHC IHC (p) WB Rabbit IgG AA 881-930 Anmelden zum Anzeigen Polyclonal 0

General

Antigen Ret Proto-Oncogene (RET) Antikörper
Epitop pTyr1096
(49), (42), (26), (26), (26), (22), (18), (15), (14), (11), (11), (8), (7), (7), (7), (7), (7), (7), (7), (6), (5), (5), (4), (4), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reaktivität Human, Maus, Ratte (Rattus)
(362), (128), (118), (9), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Wirt Kaninchen
(256), (104), (5), (2), (1), (1)
Klonalität
Polyklonal
Konjugat Dieser Ret Proto-Oncogene Antikörper ist unkonjugiert
(16), (14), (14), (12), (9), (9), (6), (6), (6), (6), (6), (5), (5), (5), (5), (5), (5), (1), (1), (1), (1), (1)
Applikation ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting (WB)
(270), (155), (122), (67), (65), (39), (34), (12), (7), (6), (6), (3), (3), (1), (1)
Hersteller Anmelden zum Anzeigen

Produktdetails anti-Ret Proto-Oncogene Antikörper

Target Details Ret Proto-Oncogene Anwendungsinformationen Handhabung Bilder
Spezifität Ret (Phospho-Tyr1096) Antibody detects endogenous levels of Ret only when phosphorylated at Tyr1096
Kreuzreaktivität Human, Maus, Ratte (Rattus)
Reinigung The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
Immunogen A synthesized peptide derived from human Ret (Phospho-Tyr1096)
Isotyp IgG
Plasmids, Primers & others

Target Details Ret Proto-Oncogene

Produktdetails anti-Ret Proto-Oncogene Antikörper Anwendungsinformationen Handhabung Bilder zurück nach oben
Antigen
Andere Bezeichnung Ret (RET Antibody Abstract)
Hintergrund

Description: Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands. Phosphorylates PTK2/FAK1. Regulates both cell death/survival balance and positional information. Required for the molecular mechanisms orchestration during intestine organogenesis, involved in the development of enteric nervous system and renal organogenesis during embryonic life, and promotes the formation of Peyer's patch-like structures, a major component of the gut-associated lymphoid tissue. Modulates cell adhesion via its cleavage by caspase in sympathetic neurons and mediates cell migration in an integrin (e.g. ITGB1 and ITGB3)-dependent manner. Involved in the development of the neural crest. Active in the absence of ligand, triggering apoptosis through a mechanism that requires receptor intracellular caspase cleavage. Acts as a dependence receptor, in the presence of the ligand GDNF in somatotrophs (within pituitary), promotes survival and down regulates growth hormone (GH) production, but triggers apoptosis in absence of GDNF. Regulates nociceptor survival and size. Triggers the differentiation of rapidly adapting (RA) mechanoreceptors. Mediator of several diseases such as neuroendocrine cancers, these diseases are characterized by aberrant integrins-regulated cell migration. Mediates, through interaction with GDF15-receptor GFRAL, GDF15-induced cell-signaling in the brainstem which induces inhibition of food-intake. Activates MAPK- and AKT-signaling pathways (PubMed:28846097, PubMed:28953886, PubMed:28846099). Isoform 1 in complex with GFRAL induces higher activation of MAPK-signaling pathway than isoform 2 in complex with GFRAL (PubMed:28846099).

Gene: RET

Molekulargewicht 175kDa
Gen-ID 5979
UniProt P07949
Pathways RTK Signalweg, Dopaminergic Neurogenesis, Regulation of Cell Size, Tube Formation

Anwendungsinformationen

Produktdetails anti-Ret Proto-Oncogene Antikörper Target Details Ret Proto-Oncogene Handhabung Bilder zurück nach oben
Applikations-hinweise WB 1:1000-3000, IHC 1:50-1:200, IF/ICC 1:100-1:500
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-Ret Proto-Oncogene Antikörper Target Details Ret Proto-Oncogene Anwendungsinformationen Bilder zurück nach oben
Format Liquid
Konzentration 1 mg/mL
Buffer Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20 °C.Stable for 12 months from date of receipt
Haltbarkeit 12 months

Bilder

Produktdetails anti-Ret Proto-Oncogene Antikörper Target Details Ret Proto-Oncogene Anwendungsinformationen Handhabung zurück nach oben
Bilder des Herstellers
Immunohistochemistry (IHC) image for anti-Ret Proto-Oncogene (RET) (pTyr1096) antibody (ABIN6271278) ABIN6271279 at 1/200 staining Human kidney tissue sections by IHC-P. The tissue was f...
Immunohistochemistry (IHC) image for anti-Ret Proto-Oncogene (RET) (pTyr1096) antibody (ABIN6271278) ABIN6271279 at 1/200 staining Mouse kidney tissue sections by IHC-P. The tissue was f...
Immunohistochemistry (IHC) image for anti-Ret Proto-Oncogene (RET) (pTyr1096) antibody (ABIN6271278) ABIN6271279 at 1/200 staining Rat kidney tissue sections by IHC-P. The tissue was for...
Immunofluorescence (fixed cells) (IF/ICC) image for anti-Ret Proto-Oncogene (RET) (pTyr1096) antibody (ABIN6271278) ABIN6271279 staining Hela cells by IF/ICC. The sample were fixed with PFA and permeab...
Western Blotting (WB) image for anti-Ret Proto-Oncogene (RET) (pTyr1096) antibody (ABIN6271278) Western blot analysis of Ret (Phospho-Tyr1096) using EGF treated HepG2 whole cell lys...