Use your antibodies-online credentials, if available.
Keine Produkte auf Ihrer Vergleichsliste.
Ihr Warenkorb ist leer.
Weitere Synonyme anzeigen
Wählen Sie die gewünschte Spezies
Ca(2 (zeige CA2 Proteine)+)/calcineurin (CaN)/nuclear factor of activated T-cells (NFAT (zeige NFATC1 Proteine)) c4 axis is required for neuritin (zeige NRN1 Proteine)-induced Kv4.2 (zeige KCND2 Proteine) transcriptional expression and potentiation of IA densities in cerebellum granule neurons.
Nfatc4 expression was coordinately upregulated by top hypoxia-activated transcription factors, while NFATc4 target genes were enriched in hypoxic neural stem cells.
results indicate that NFAT (zeige NFATC1 Proteine) is a BACE1 (zeige BACE Proteine) transcription factor. Our study suggests that inhibition of NFAT (zeige NFATC1 Proteine)-mediated BACE1 (zeige BACE Proteine) expression may be a valuable drug target for AD therapy
our results suggest that activation of NHE1 (zeige SLC9A1 Proteine) induces hypertrophy through the activation of NFAT3/Gata4 (zeige GATA4 Proteine) and OPN (zeige SPP1 Proteine) expression
L-carnitine reversed the activation of NFAT3 and PPARa (zeige PPARA Proteine) caused by carboplatin through altering the phosphorylation of PTEN and AMPK (zeige PRKAA1 Proteine).
Disrupting the calcineurin-NFAT (zeige NFATC1 Proteine) axis by either genetic or pharmacologic approaches confers resistance to the development of social stress-induced voiding and dysfunction.
The NFATc4-dependent increase in hippocampal neurogenesis after GABAA (zeige GABRg1 Proteine) receptor stimulation is required for suppression of anxiety response.
IL-13 (zeige IL13 Proteine) specifically induced NFAT3 activation through promoting its dephosphorylation in air-liquid interface cultures of tracheal epithelial cells (mTECs).
Data suggest that expression of Itpr1 (inositol 1,4,5-triphosphate receptor 1 (zeige ITPR1 Proteine)) in cerebral cortex neurons is regulated by dopamine D2 receptors; Itpr1 (zeige ITPR1 Proteine) is up-regulated via increased binding of NFATc4 and transcription factor AP-1 (zeige JUN Proteine) to Itpr1 (zeige ITPR1 Proteine) promoter.
these results reveal a novel PI3K-independent role for p85alpha in controlling VEGF (zeige VEGFA Proteine) induction during the cellular UVB response by regulating NFAT3 activity.
NFATc1 (zeige NFATC1 Proteine) knockdown strongly reduced the number and the surface area of myotubes, NFATc4 knockdown increased the surface area of myotubes and reduced the pool of reserve cells.
TBX5 (zeige TBX5 Proteine) deficiency-mediated downregulation of NFAT3 is crucial for the high cytokine-producing activity of T cells
These results provided evidence supporting the oncogenic potential of NFAT3 and suggested that CDK3 (zeige CDK3 Proteine)-mediated phosphorylation of NFAT3 has an important role in skin tumorigenesis.
Data indicate that RNA interference of NFAT (zeige NFATC1 Proteine) isoforms NFATc1 (zeige NFATC1 Proteine), NFATc2 (zeige NFAT1 Proteine), NFATc3 (zeige NFATC3 Proteine) and NFATc4 regulate gene expression differentially in human retinal microvascular endothelial cells (HRMEC).
NFAT3 expression plays a role in regulating CXCR4 (zeige CXCR4 Proteine) expression.
Suggest nuclear NF-AT3 and NF-AT4 (zeige NFATC3 Proteine) participates in atrial structural remodeling, and that PICP and TGF-beta1 (zeige TGFB1 Proteine) levels may be sensitive serum biomarkers to estimate atrial structural remodeling with atrial fibrillation.
This is the first study to provide evidence of new and differential roles for NFAT3 and SMAD3 (zeige SMAD3 Proteine) in the osteoarthritis process in the regulation of miR (zeige MLXIP Proteine)-140 transcription
Expression level of PPP3R1 (zeige PPP3R1 Proteine) and GATA4 (zeige GATA4 Proteine), and NFATC4 genes for transcription factors did not differ in studied subgroups of patients.
Data indicate that NFATc3 (zeige NFATC3 Proteine) undergoes rapid dephosphorylation and nuclear translocation that are essentially complete within 20 min, although NFATc4 remains phosphorylated and localized to the cytosol.
The product of this gene is a member of the nuclear factors of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation and an inducible nuclear component. Other members of this family of nuclear factors of activated T cells also participate in the formation of this complex. The product of this gene plays a role in the inducible expression of cytokine genes in T cells, especially in the induction of the IL-2 and IL-4. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
cytoplasmic nuclear factor of activated T-cells 4
, nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
, nuclear factor of activated T-cells, cytoplasmic 4-like
, T-cell transcription factor NFAT3
, nuclear factor of activated T-cells, cytoplasmic 4
, transcription complex subunit NF-ATc4
, T cell transcription factor NFAT3