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|Antigen||Fibroblast Growth Factor 8 (Androgen-Induced) (FGF8) Antikörper|
|Epitop||AA 23-233 Alternativen|
|Reaktivität||Human, Maus, Ratte (Rattus) Alternativen|
|Konjugat||Dieser FGF8 Antikörper ist unkonjugiert Alternativen|
ELISA, Western Blotting (WB)
|Hersteller||Anmelden zum Anzeigen|
Produktdetails anti-FGF8 AntikörperTarget Details FGF8 Anwendungsinformationen Handhabung Bilder
|Verwendungszweck||Rabbit IgG polyclonal antibody for FGF8 detection. Tested with WB, Direct ELISA in Human,Mouse,Rat.|
|Kreuzreaktivität (Details)||No cross reactivity with other proteins.|
Rabbit IgG polyclonal antibody for FGF8 detection. Tested with WB, Direct ELISA in Human,Mouse,Rat.
Gene Name: fibroblast growth factor 8
Protein Name: Fibroblast growth factor 8
|Reinigung||Immunogen affinity purified.|
|Immunogen||E. coli-derived human FGF8 recombinant protein (Position: Q23-R233).|
Target Details FGF8Produktdetails anti-FGF8 Antikörper Anwendungsinformationen Handhabung Bilder zurück nach oben
|Andere Bezeichnung||FGF8 (FGF8 Antibody Abstract)|
Fibroblast growth factor 8 (androgen-induced), also known as FGF8 or AIGF, is a human gene which maps to 10q24. The protein encoded by this gene is secreted proteins that interact with FGF tyrosine kinase receptors to mediate growth and development. This protein is known to be a factor that supports androgen and anchorage independent growth of mammary tumor cells. Overexpression of this gene has been shown to increase tumor growth and angiogensis. The temporal and spatial patterns of this gene expression suggest that FGF8 is involved in gastrulation, regionalization of the brain, and organogenesis of the limb and face as an embryonic epithelial factor. The adult expression of FGF8 is restricted to gonads, including testes and ovaries. FGF8 stimulated growth of human prostate carcinoma cells and mouse fibroblasts and mammary carcinoma cells in a dose-dependent manner. It also may play an important role in growth and patterning of limbs, face, and central nervous system. FGF8 is expressed in increased levels in breast cancer and in lactating human breast, it was also detected in human milk. A survey of other normal tissues showed that FGF8 is expressed in the proliferative cells of the skin and epithelial cells in colon, ovary, fallopian tube, and uterus.
Synonyms: Fibroblast growth factor 8, FGF-8, Androgen-induced growth factor, AIGF, Heparin-binding growth factor 8, HBGF-8, FGF8, AIGF
|Pathways||RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Dopaminergic Neurogenesis|
AnwendungsinformationenProduktdetails anti-FGF8 Antikörper Target Details FGF8 Handhabung Bilder zurück nach oben
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users.
Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot.
|Beschränkungen||Nur für Forschungszwecke einsetzbar|
HandhabungProduktdetails anti-FGF8 Antikörper Target Details FGF8 Anwendungsinformationen Bilder zurück nach oben
|Rekonstitution||Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.|
|Buffer||Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.|
|Vorsichtsmaßnahmen||This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|
|Lagerung||4 °C,-20 °C|
|Informationen zur Lagerung||
At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.