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Human FGF21 ELISA Kit für Sandwich ELISA - ABIN857064
Chen, Zhao, Wan, Ran, Qin, Wang, Gao, Shu, Zhang, Liu, Zhang, Zhu, Mi: Dihydromyricetin improves glucose and lipid metabolism and exerts anti-inflammatory effects in nonalcoholic fatty liver disease: A randomized controlled trial. in Pharmacological research : the official journal of the Italian Pharmacological Society 2015
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Human FGF21 ELISA Kit für Sandwich ELISA - ABIN612700
Nishimura, Nakatake, Konishi, Itoh: Identification of a novel FGF, FGF-21, preferentially expressed in the liver. in Biochimica et biophysica acta 2000
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Mouse (Murine) FGF21 ELISA Kit für Sandwich ELISA - ABIN2859244
Liu, Pan, Chen, Yang, Zhao, Jia, Zhu, Zhang, Gao, Li, Han, Duan: Administration of Danhong Injection to diabetic db/db mice inhibits the development of diabetic retinopathy and nephropathy. in Scientific reports 2015
Human FGF21 ELISA Kit für Sandwich ELISA - ABIN2684258
Suzuki, Lee, Vázquez-Medina, Viscarra, Crocker, Ortiz: Plasma FGF21 concentrations, adipose fibroblast growth factor receptor-1 and β-klotho expression decrease with fasting in northern elephant seals. in General and comparative endocrinology 2015
Cow (Bovine) FGF21 ELISA Kit für Sandwich ELISA - ABIN1000145
Farney, Mamedova, Coetzee, KuKanich, Sordillo, Stoakes, Minton, Hollis, Bradford: Anti-inflammatory salicylate treatment alters the metabolic adaptations to lactation in dairy cattle. in American journal of physiology. Regulatory, integrative and comparative physiology 2013
Human FGF21 ELISA Kit für Sandwich ELISA - ABIN418605
Xu, Niu, Yu, Xia, Gong, Wang: Associations between FGF21, osteonectin and bone turnover markers in type 2 diabetic patients with albuminuria. in Journal of diabetes and its complications 2016
Pig (Porcine) FGF21 ELISA Kit für Sandwich ELISA - ABIN649220
Varady, Ringseis, Eder: Dietary moderately oxidized oil induces expression of fibroblast growth factor 21 in the liver of pigs. in Lipids in health and disease 2012
Mouse (Murine) FGF21 ELISA Kit für Competition ELISA - ABIN2761940
Bae, Min, Kim, Lee, Park: Alpha lipoic acid induces hepatic fibroblast growth factor 21 expression via up-regulation of CREBH. in Biochemical and biophysical research communications 2014
Mouse (Murine) FGF21 ELISA Kit für Sandwich ELISA - ABIN1081421
Min, Bae, Jung, Choi, Kim, Kim, Jeon, Kim, Lee, Park: Orphan nuclear receptor Nur77 mediates fasting-induced hepatic fibroblast growth factor 21 expression. in Endocrinology 2014
The ability of FGF21 to decrease LDL cholesterol has now been traced to at least two mechanisms: a suppression of hepatocyte expression of sterol response element-binding protein-2 (SREBP-2 (zeige SREBF2 ELISA Kits)), which in turn leads to a reduction in cholesterol synthesis; and up-regulated expression of hepatocyte LDL receptors, reflecting inhibition of a mechanism that promotes proteasomal degradation of these receptors. [review]
The objective of this review is to compile existing information about the mechanisms that could allow the control of endogenous FGF21 levels in order to obtain the beneficial metabolic effects of FGF21 by inducing its production instead of doing it by pharmacological administration. [review]
Fibroblast growth factor 21 (FGF21) gene expression is altered by a wide array of physiological, metabolic, and environmental factors. [review]
As there was no significant association between FGF-21 and growth or IGF-1 (zeige IGF1 ELISA Kits) both in cross-sectional and longitudinal analyses, these findings do not support the hypothesis that FGF-21 is involved in growth of obese children.
This mini-review aims to summarize the current state of knowledge about the role of FGF21 in cardiovascular disorders, and discuss the molecular mechanism underlying the anti-atherogenic properties of this compound. [review]
FGF21 has received particular attention because of its key role in carbohydrate, lipids, and energy balance regulation. FGF21 has an anti-oxidant function in human metabolic diseases which contribute to understanding the FGF21 compensatory increment in obesity, the metabolic syndrome, and type 2 diabetes. [review]
cholestasis could induce FGF21 expression in FXR (zeige NR1H4 ELISA Kits) dependent manner
Serum concentrations of FGF21 are elevated in patients with non-HIV lipodystrophy with adipose tissue and liver being potential sources of increased production. TG and fibrate treatment are independent positive predictors of circulating FGF21.
FGF21 concentration in plasma is increased in patients with obesity, insulin (zeige INS ELISA Kits) resistance, and metabolic syndrome. Recent findings suggest that such increment protects tissue from an increased oxidative stress environment. (Review)
FGF21 appears to act in a paracrine manner to increase glucose uptake under low insulin (zeige INS ELISA Kits) conditions, but it does not contribute to the resistance to diet-induced obesity.
The present study shows that expression of the FGF21 gene is strongly up-regulated during the transition period; the up-regulation of FGF21 might play an important role in the adaptation of liver metabolism during early lactation in dairy cows such as in other species.
RESULTS: The results showed that serum FGF-21 levels were significantly higher in both groups treated with a controlled-energy diet, while FGF-21 levels in both groups treated with moderate-energy diet were low.
liver-derived FGF21 regulates the use of lipid reserves during lactation via focal actions on liver and white adipose tissue.
FGF21 deletion aggravates aortic remodeling and cell death probably via exacerbation of aortic inflammation and oxidative stress in type 1 diabetes.
This study demonstrates that FGF21 action is necessary to achieve the full metabolic benefits of exercise during chronic HF feeding.
mTORC1 mediated many of the beneficial actions of FGF21 in vitro, including UCP1 (zeige UCP1 ELISA Kits) and FGF21 induction, increased adiponectin secretion, and enhanced glucose uptake without any adverse effects on insulin (zeige INS ELISA Kits) action.
FGF21 has a role in promoting remyelination in the central nervous system
Data suggest that expression of Fgf21 in liver responds acutely to dietary protein intake; low-protein high-carbohydrate diet induces Fgf21 expression; high-protein low-carbohydrate diet reduces Fgf21 expression; Fgf21 expression/secretion in cultured hepatocytes appears to be controlled by glucose but not amino acids.
These findings reveal a previously unappreciated anti-inflammatory role for FGF21 in adipose tissue, but do not support that FGF21 is necessary for exercise-mediated anti-inflammatory effects.
our results reveal that ERRgamma (zeige ESRRG ELISA Kits), induced via activation of the hepatic CB1 (zeige CNR1 ELISA Kits) receptor, is a regulator of hepatic FGF21 gene expression and secretion.
OPA1 (zeige MED12 ELISA Kits) mutant mice are resistant to age- and diet-induced weight gain and insulin (zeige INS ELISA Kits) resistance, by mechanisms that involve activation of endoplasmic reticulum stress and secretion of fibroblast growth factor 21 (FGF21) from skeletal muscle, resulting in increased metabolic rates and improved whole-body insulin (zeige INS ELISA Kits) sensitivity.
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. The function of this growth factor has not yet been determined.
fibroblast growth factor 21