anti-Human DEPTOR Antikörper für Immunohistochemistry (Paraffin-embedded Sections)

Recommended DEPTOR Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
DEP Domain Containing MTOR-Interacting Protein (DEPTOR) Antikörper
  • DEP.6
  • DEPDC6
  • 4731402B04Rik
  • 9130412E02Rik
  • D15Ertd336e
  • D15Ertd597e
  • Depdc6
  • Depdc6-001
  • Depdc6-002
  • R75183
  • mKIAA4200
  • RGD1561030
  • RAPGEF4
  • DEP domain containing MTOR interacting protein
  • DEP domain containing MTOR-interacting protein
  • DEPTOR
  • Deptor
Epitop
AA 62-107
16
14
14
8
4
3
1
1
1
1
1
1
1
1
1
Reaktivität
Human, Maus
69
40
15
7
4
4
2
2
2
2
2
2
2
1
Wirt
Kaninchen
60
8
1
Klonalität
Polyklonal
Konjugat
Dieser DEPTOR Antikörper ist unkonjugiert
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Applikation
Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
52
22
21
15
15
14
12
1
Optionen
Hersteller
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Bilder

Produktnummer ABIN1387597
$ 318.45
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
1 ABIN1415968 IHC (p) WB HRP Rabbit IgG AA 62-107 Anmelden zum Anzeigen Polyclonal 0
1 ABIN2620009 ELISA IHC IHC (p) WB Rabbit IgG Internal Region Anmelden zum Anzeigen Polyclonal 0
1 ABIN1398097 IHC (p) WB Biotin Rabbit IgG AA 62-107 Anmelden zum Anzeigen Polyclonal 0
1 ABIN1733593 ICC IF IHC (p) WB Rabbit IgG Internal Region, AA 10-200 Anmelden zum Anzeigen Polyclonal 0
1 ABIN2962521 IHC (p) ELISA WB Rabbit Internal Region Anmelden zum Anzeigen Polyclonal 0

General

Antigen DEP Domain Containing MTOR-Interacting Protein (DEPTOR) Antikörper
Epitop AA 62-107
(16), (14), (14), (8), (4), (3), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reaktivität Human, Maus
(69), (40), (15), (7), (4), (4), (2), (2), (2), (2), (2), (2), (2), (1)
Wirt Kaninchen
(60), (8), (1)
Klonalität
Polyklonal
Konjugat Dieser DEPTOR Antikörper ist unkonjugiert
(2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Applikation Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(52), (22), (21), (15), (15), (14), (12), (1)
Pubmed 1 Publikation vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-DEPTOR Antikörper

Target Details DEPTOR Anwendungsinformationen Handhabung Referenzen für anti-DEPTOR Antikörper (ABIN1387597) Bilder
Reinigung Purified by Protein A.
Immunogen KLH conjugated synthetic peptide derived from human DEPTOR/DEPDC6
Isotyp IgG
Plasmids, Primers & others

Target Details DEPTOR

Produktdetails anti-DEPTOR Antikörper Anwendungsinformationen Handhabung Referenzen für anti-DEPTOR Antikörper (ABIN1387597) Bilder zurück nach oben
Antigen
Andere Bezeichnung Deptor (DEPTOR Antibody Abstract)
Hintergrund

DEPTOR (DEP domain containing MTOR-interacting protein), also known as DEP.6 or DEPDC6 (DEP domain-containing protein 6), is a 409 amino acid protein that negatively regulates mTORC1 and mTORC2 pathways. DEPTOR interacts with FRAP via its PDZ domain, and undergoes post-translational phosphorylation. Containing two DEP domains and one PDZ (DHR) domain, DEPTOR is encoded by a gene that maps to human chromosome 8q24.12. Chromosome 8 consists of nearly 146 million base pairs, encodes over 800 genes and is associated with a variety of diseases and malignancies. Schizophrenia, bipolar disorder, Trisomy 8, Pfeiffer syndrome, congenital hypothyroidism, Waardenburg syndrome and some leukemias and lymphomas are thought to occur as a result of defects in specific genes that map to chromosome 8.

Synonyms: DEP.6, DEPDC6, DEP domain-containing mTOR-interacting protein, DEP domain-containing protein 6, DEPTOR

Gen-ID 64798
UniProt Q8TB45
Pathways PI3K-Akt Signalweg, RTK Signalweg, Regulation of Cell Size

Anwendungsinformationen

Produktdetails anti-DEPTOR Antikörper Target Details DEPTOR Handhabung Referenzen für anti-DEPTOR Antikörper (ABIN1387597) Bilder zurück nach oben
Applikations-hinweise WB 1:100-1000
IHC-P 1:100-500
IF(IHC-P) 1:50-200
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-DEPTOR Antikörper Target Details DEPTOR Anwendungsinformationen Referenzen für anti-DEPTOR Antikörper (ABIN1387597) Bilder zurück nach oben
Format Liquid
Konzentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C
Haltbarkeit 12 months

Referenzen für anti-DEPTOR Antikörper (ABIN1387597)

Produktdetails anti-DEPTOR Antikörper Target Details DEPTOR Anwendungsinformationen Handhabung Bilder zurück nach oben
Produkt verwendet in:

Liu, Zhang, Liu, Li, Zhang, Li, Liu, Huang, Shen, Gu, Gao, Wu, Wu: "High DEPTOR expression correlates with poor prognosis in patients with esophageal squamous cell carcinoma." in: OncoTargets and therapy, Vol. 8, pp. 3449-55, 2015 Von den Autoren verwendete Methode: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (Probematerial (Species): Human).

Bilder

Produktdetails anti-DEPTOR Antikörper Target Details DEPTOR Anwendungsinformationen Handhabung Referenzen für anti-DEPTOR Antikörper (ABIN1387597) zurück nach oben
Bilder des Herstellers
Immunohistochemistry (IHC) image for anti-DEP Domain Containing MTOR-Interacting Protein (DEPTOR) (AA 62-107) antibody (ABIN1387597) Formalin-fixed and paraffin embedded human colon carcinoma labeled with Anti DEPTOR/D...
Immunohistochemistry (IHC) image for anti-DEP Domain Containing MTOR-Interacting Protein (DEPTOR) (AA 62-107) antibody (ABIN1387597) Formalin-fixed and paraffin embedded rat liver labeled with Anti DEPTOR/DEPDC6 Polycl...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-DEP Domain Containing MTOR-Interacting Protein (DEPTOR) (AA 62-107) antibody (ABIN1387597) Paraformaldehyde-fixed, paraffin embedded rat brain, Antigen retrieval by boiling in ...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-DEP Domain Containing MTOR-Interacting Protein (DEPTOR) (AA 62-107) antibody (ABIN1387597) Paraformaldehyde-fixed, paraffin embedded human colon cancer, Antigen retrieval by bo...