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(AMD1)-mediated mRNA processing and cell adhesion activated & inhibited transition mechanisms
AMD1 is upregulated in human prostate cancer with activated mTORC1
AMD1 gene variants previously found to associate among Indian children did not associate with risk of obesity or obesity-related quantitative measures among Caucasian children and juvenile men from Denmark.
Gene expression studies have identified altered expression of AMD1 in suicide completers with a history of mood disorders.
This study demomistrated that H3K4me3 modification plays an important role in up regulation of AMD1 in prefrontal cortex.
Genetic variant of AMD1 is associated with obesity.
Overexpression of S-adenosylmethionine decarboxylase in rodent fibroblasts led to aggressive transformants.
Decreased AMD1 is associated with prostate cancer.
AdoMetDC is ubiquitinated and degraded by the 26 S proteasome
The adhesion-dependent expression of SAM (zeige TTN Proteine)-DC and ODC (zeige ODC1 Proteine) contributes to extracellular matrix-dependent salivary gland cell differentiation.
Amd1 is a major regulator of embryonic stem cell self-renewal and that its essential role lies in its regulation of Myc (zeige MYC Proteine) levels within the cell
This gene encodes an important intermediate enzyme in polyamine biosynthesis. The polyamines spermine, spermidine, and putrescine are low-molecular-weight aliphatic amines essential for cellular proliferation and tumor promotion. Two alternatively spliced transcript variants that encode different proteins have been identified. Pseudogenes of this gene are found on chromosomes 5, 6, 10, X and Y.
, S-adenosyl decarboxylase
, adenosylmethionine decarboxylase 1
, S-adenosylmethionine decarboxylase
, S-adenosylmethionine decarboxylase proenzyme
, s-adenosylmethionine decarboxylase proenzyme-like
, S-adenosylmethionine decarboxylase 1
, S-Adenosylmethionine decarboxylase 1B
, S-adenosylmethionine decarboxylase 1A
, S-Adenosylmethionine decarboxylase 1A
, adenosylmethionine decarboxylase 1A
, S-adenosylmethionine decarboxylase proenzyme 1
, adoMetDC 1