anti-Maus Discs, Large Homolog 4 (Drosophila) Antikörper für Western Blotting

Recommended Discs, Large Homolog 4 (Drosophila) Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Discs, Large Homolog 4 (Drosophila) (DLG4) Antikörper
  • 11
  • CG1725
  • CG1730
  • CPD
  • DLG
  • DLG-A
  • Discs-large
  • Dlg
  • Dlg-A
  • Dlg1
  • DlgA
  • Dmel\\CG1725
  • Drodlg
  • PSD95
  • SAP97
  • anon-EST:Posey93
  • anon-WO03040301.258
  • anon-WO03040301.260
  • anon-WO03040301.268
  • d. lg.-1
  • dlg
  • dlg-1
  • dlg-A
  • dlgA
  • dlgS97
  • l(1)10Bf
  • l(1)G0276
  • l(1)G0342
  • l(1)G0456
  • l(1)G19
  • l(1)L11
  • l(1)bwn
  • l(1)d.lg-1
  • l(1)d.lg.-1
  • l(1)discs large
  • l(1)dlg
  • l(1)dlg-1
  • l(1)dlg1
  • l(1)l.pr.-2
  • l(1)lpr-2
  • misb
  • dlgh4
  • psd95
  • sap90
  • sap-90
  • LLGL1
  • Dlgh4
  • PSD-95
  • SAP90
  • SAP90A
  • Sap90
  • SAP-90
  • DLG4
  • discs large 1
  • discs, large homolog 4
  • discs large MAGUK scaffold protein 4
  • discs, large homolog 4b (Drosophila)
  • discs, large homolog 4 (Drosophila)
  • dlg1
  • dlg4
  • DLG4
  • dlg4b
  • Dlg4
Reaktivität
Rind (Kuh), Human, Maus, Ratte (Rattus)
271
262
256
131
14
14
5
5
4
4
3
3
2
2
1
1
1
1
Wirt
Maus
183
120
15
1
Klonalität
Monoklonal
Konjugat
Atto 565
11
11
9
8
8
7
6
6
6
6
6
6
6
6
6
5
5
5
4
3
3
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
1
1
Applikation
Antibody Array (AA), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting (WB)
266
172
111
90
50
42
39
35
31
23
19
15
7
2
1
1
1
1
Optionen
Hersteller
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Bilder

Produktnummer ABIN2484824
$ 487.50
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
25.558289 ABIN2484822 AA ICC IF IHC WB Atto 390 Mouse IgG1 Anmelden zum Anzeigen 7E3 2
25.558289 ABIN2484827 AA ICC IF IHC WB Atto 655 Mouse IgG1 Anmelden zum Anzeigen 7E3 2
25.558289 ABIN2484823 AA ICC IF IHC WB Atto 488 Mouse IgG1 Anmelden zum Anzeigen 7E3 2
25.558289 ABIN2484832 AA ICC IF IHC WB Biotin Mouse IgG1 Anmelden zum Anzeigen 7E3 2
25.558289 ABIN2484826 AA ICC IF IHC WB Atto 633 Mouse IgG1 Anmelden zum Anzeigen 7E3 2
25.558289 ABIN2484828 AA ICC IF IHC WB Atto 680 Mouse IgG1 Anmelden zum Anzeigen 7E3 2
25.558289 ABIN2484829 AA ICC IF IHC WB Atto 700 Mouse IgG1 Anmelden zum Anzeigen 7E3 2
25.558289 ABIN2484831 AA ICC IF IHC WB APC Mouse IgG1 Anmelden zum Anzeigen 7E3 2
25.558289 ABIN2484834 AA ICC IF IHC WB HRP Mouse IgG1 Anmelden zum Anzeigen 7E3 2
25.558289 ABIN2484833 AA ICC IF IHC WB FITC Mouse IgG1 Anmelden zum Anzeigen 7E3 2
25.558289 ABIN2484835 AA ICC IF IHC WB PE-Atto 594 Mouse IgG1 Anmelden zum Anzeigen 7E3 2
25.558289 ABIN2484837 AA ICC IF IHC WB PE Mouse IgG1 Anmelden zum Anzeigen 7E3 2
25.558289 ABIN2484836 AA ICC IF IHC WB PerCP Mouse IgG1 Anmelden zum Anzeigen 7E3 2
25.558289 ABIN2484838 AA ICC IF IHC WB Streptavidin Mouse IgG1 Anmelden zum Anzeigen 7E3 2
25.558289 ABIN2484825 AA ICC IF IHC WB Atto 594 Mouse IgG1 Anmelden zum Anzeigen 7E3 2
25.558289 ABIN2484830 AA ICC IF IHC WB Alkaline Phosphatase (AP) Mouse IgG1 Anmelden zum Anzeigen 7E3 2
22.558289 ABIN2484818 AA ICC IF IHC WB PE-Atto 594 Mouse IgG2a Anmelden zum Anzeigen 6G6 2
22.558289 ABIN2484808 AA ICC IF IHC WB Atto 594 Mouse IgG2a Anmelden zum Anzeigen 6G6 2
22.558289 ABIN2484810 AA ICC IF IHC WB Atto 655 Mouse IgG2a Anmelden zum Anzeigen 6G6 2
22.558289 ABIN2484814 AA ICC IF IHC WB APC Mouse IgG2a Anmelden zum Anzeigen 6G6 2

General

Antigen Discs, Large Homolog 4 (Drosophila) (DLG4) Antikörper
Reaktivität Rind (Kuh), Human, Maus, Ratte (Rattus)
(271), (262), (256), (131), (14), (14), (5), (5), (4), (4), (3), (3), (2), (2), (1), (1), (1), (1)
Wirt Maus
(183), (120), (15), (1)
Klonalität (Klon)
Monoklonal   ( )
Konjugat Atto 565
(11), (11), (9), (8), (8), (7), (6), (6), (6), (6), (6), (6), (6), (6), (6), (5), (5), (5), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1)
Applikation Antibody Array (AA), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting (WB)
(266), (172), (111), (90), (50), (42), (39), (35), (31), (23), (19), (15), (7), (2), (1), (1), (1), (1)
Pubmed 2 Publikationen vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails

Antigendetails Anwendungsinformationen Handhabung Referenzen Bilder
Spezifität Detects ~100 kDa. An additional protein of >100 kDa is also detected. Additional cross-reactive bands are detected at ~75 kDa and 50 kDa in rat and mouse samples.
Reinigung Protein G Purified
Immunogen Recombinant rat PSD-95
Klon 7E3
Isotyp IgG1

Antigendetails

Produktdetails Anwendungsinformationen Handhabung Referenzen Bilder zurück nach oben
Antigen
Andere Bezeichnung PSD 95 (DLG4 Antibody Abstract)
Hintergrund Postsynaptic Density protein 95 (PSD95), also known as Synapse associated protein 90 kDa, is a member of the membrane-associated guanylate kinase (MAGUK) family of proteins. PSD95 is a scaffolding protein and is involved in the assembly and function of the postsynaptic density complex (1). These family members consist of an N-terminal variable segment followed by three amino-terminal PDZ domains, an upstream SH3 domain and an inactive carboxyl-terminal guanylate kinase (GK) domain. The first and second PDZ domain localize NMDA receptors and K+ channels to synapses, and the third binds to neuroligins which are neuronal cell adhesion molecules that interact with b-neurexins and form intercellular junctions. PSD-95 also binds to neuronal nitric oxide synthase, possibly through interactions between PDZ domains present on both proteins (2). Thus different PDZ domains of PSD-95 might be specialized for distinct functions (3, 4). PSD95 participates in synaptic targeting of AMPA receptors through an indirect manner involving Stargazin and related transmembrane AMPA receptor regulatory proteins (TARPs) (5). The protein is implicated in experience dependent plasticity and plays an indispensable role in learning (6). Mutations in PSD95 are associated with autism (7).
Gen-ID 29495
NCBI Accession NP_062567
UniProt P31016
Pathways Regulation of Muscle Cell Differentiation, Synaptic Membrane, Skeletal Muscle Fiber Development, Asymmetric Protein Localization, Regulation of long-term Neuronal Synaptic Plasticity

Anwendungsinformationen

Produktdetails Antigendetails Handhabung Referenzen Bilder zurück nach oben
Applikations-hinweise
  • WB (1:1000)
  • IHC (1:1000)
  • ICC/IF (1:100)
  • optimal dilutions for assays should be determined by the user.
Kommentare

1 μg/ml was sufficient for detection of PSD-95 on 20 μg rat brain tissue extract by ECL immunoblot analysis using Goat Anti-Mouse IgG: HRP as the secondary.

Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails Antigendetails Anwendungsinformationen Referenzen Bilder zurück nach oben
Format Liquid
Konzentration 1 mg/mL
Buffer PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C

Referenzen

Produktdetails Antigendetails Anwendungsinformationen Handhabung Bilder zurück nach oben
Allgemeine Veröffentlichungen

Cline: "Synaptogenesis: a balancing act between excitation and inhibition." in: Current biology : CB, Vol. 15, Issue 6, pp. R203-5, 2005

Yao, Gainetdinov, Arbuckle, Sotnikova, Cyr, Beaulieu, Torres, Grant, Caron: "Identification of PSD-95 as a regulator of dopamine-mediated synaptic and behavioral plasticity." in: Neuron, Vol. 41, Issue 4, pp. 625-38, 2004

Bilder

Produktdetails Antigendetails Anwendungsinformationen Handhabung Referenzen zurück nach oben
Bilder des Herstellers
Immunohistochemistry (IHC) image for anti-Discs, Large Homolog 4 (Drosophila) (DLG4) antibody (Atto 565) (ABIN2484824) Immunohistochemistry analysis using Mouse Anti-PSD95 Monoclonal Antibody, Clone 7E3 ....
Immunofluorescence (fixed cells) (IF/ICC) image for anti-Discs, Large Homolog 4 (Drosophila) (DLG4) antibody (Atto 565) (ABIN2484824) Immunocytochemistry/Immunofluorescence analysis using Mouse Anti-PSD95 Monoclonal Ant...
Immunohistochemistry (IHC) image for anti-Discs, Large Homolog 4 (Drosophila) (DLG4) antibody (Atto 565) (ABIN2484824) Immunohistochemistry analysis using Mouse Anti-PSD95 Monoclonal Antibody, Clone 7E3 ....
Western Blotting (WB) image for anti-Discs, Large Homolog 4 (Drosophila) (DLG4) antibody (Atto 565) (ABIN2484824) Western Blot analysis of Rat brain membrane lysate showing detection of PSD95 protein...