anti-Human Discs, Large Homolog 4 (Drosophila) Antikörper für Flow Cytometry

Recommended Discs, Large Homolog 4 (Drosophila) Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Discs, Large Homolog 4 (Drosophila) (DLG4) Antikörper
  • 11
  • CG1725
  • CG1730
  • CPD
  • DLG
  • DLG-A
  • Discs-large
  • Dlg
  • Dlg-A
  • Dlg1
  • DlgA
  • Dmel\\CG1725
  • Drodlg
  • PSD95
  • SAP97
  • anon-EST:Posey93
  • anon-WO03040301.258
  • anon-WO03040301.260
  • anon-WO03040301.268
  • d. lg.-1
  • dlg
  • dlg-1
  • dlg-A
  • dlgA
  • dlgS97
  • l(1)10Bf
  • l(1)G0276
  • l(1)G0342
  • l(1)G0456
  • l(1)G19
  • l(1)L11
  • l(1)bwn
  • l(1)d.lg-1
  • l(1)d.lg.-1
  • l(1)discs large
  • l(1)dlg
  • l(1)dlg-1
  • l(1)dlg1
  • l(1)l.pr.-2
  • l(1)lpr-2
  • misb
  • dlgh4
  • psd95
  • sap90
  • sap-90
  • LLGL1
  • Dlgh4
  • PSD-95
  • SAP90
  • SAP90A
  • Sap90
  • SAP-90
  • DLG4
  • discs large 1
  • discs, large homolog 4
  • discs large MAGUK scaffold protein 4
  • discs, large homolog 4b (Drosophila)
  • discs, large homolog 4 (Drosophila)
  • dlg1
  • dlg4
  • DLG4
  • dlg4b
  • Dlg4
Reaktivität
Rind (Kuh), Human, Maus, Ratte (Rattus)
271
262
256
131
14
14
5
5
4
4
3
3
2
2
1
1
1
1
Wirt
Maus
183
120
15
1
Klonalität
Monoklonal
Konjugat
Unkonjugiert
11
11
9
8
8
7
6
6
6
6
6
6
6
6
6
6
5
5
4
3
3
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
1
1
Applikation
Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Western Blotting (WB)
266
173
112
91
50
42
39
36
31
23
18
14
7
2
1
1
1
1
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Produktnummer ABIN5550982
$ 490.60
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
1 ABIN4904877 FACS ICC IHC IP WB Rabbit IgG Anmelden zum Anzeigen 0
1 ABIN2338904 IC FACS IP WB Rabbit IgG N-Term Anmelden zum Anzeigen 9i189 0
1 ABIN2338918 IC FACS IP ELISA WB Rabbit IgG N-Term Anmelden zum Anzeigen 9E457 0

General

Antigen Discs, Large Homolog 4 (Drosophila) (DLG4) Antikörper
Reaktivität Rind (Kuh), Human, Maus, Ratte (Rattus)
(271), (262), (256), (131), (14), (14), (5), (5), (4), (4), (3), (3), (2), (2), (1), (1), (1), (1)
Wirt Maus
(183), (120), (15), (1)
Klonalität (Klon)
Monoklonal   ( )
Konjugat Unkonjugiert
(11), (11), (9), (8), (8), (7), (6), (6), (6), (6), (6), (6), (6), (6), (6), (6), (5), (5), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1)
Applikation Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Western Blotting (WB)
(266), (173), (112), (91), (50), (42), (39), (36), (31), (23), (18), (14), (7), (2), (1), (1), (1), (1)
Hersteller Anmelden zum Anzeigen

Produktdetails

Antigendetails Anwendungsinformationen Handhabung Bilder
Spezifität This antibody detects an ~100 kDa protein corresponding to the apparent molecular mass of PSD-95 on SDS-PAGE immunoblots. An additional protein of > 100 kDa is also detected. Additional cross-reactive bands are detected at ~75 kDa and 50 kDa in rat and mouse samples.
Kreuzreaktivität (Details) Species reactivity (tested):Mouse, Rat, Bovine, Human
Produktmerkmale Synonyms: DLGH4, PSD-95, Disks large homolog 4, SAP90, SAP-90, Postsynaptic density protein 95,Synapse-associated protein 90
Reinigung Protein G chromatography
Immunogen Recombinant rat PSD-95
Klon 6G6
Isotyp IgG2a

Antigendetails

Produktdetails Anwendungsinformationen Handhabung Bilder zurück nach oben
Antigen
Andere Bezeichnung DLG4 / PSD95 (DLG4 Antibody Abstract)
Hintergrund Postsynaptic Density protein 95 (PSD95), also known as Synapse associated protein 90 kDa, is a member of the membrane-associated guanylate kinase (MAGUK) family of proteins. PSD95 is a scaffolding protein and is involved in the assembly and function of the postsynaptic density complex (1). These family members consist of an Nterminal variable segment followed by three aminoterminal PDZ domains, an upstream SH3 domain and an inactive carboxyl-terminal guanylate kinase (GK) domain. The first and second PDZ domain localize NMDA receptors and K+ channels to synapses, and the third binds to neuroligins which are neuronal cell adhesion molecules that interact with b-neurexins and form intercellular junctions. PSD-95 also binds to neuronal nitric oxide synthase, possibly through interactions between PDZ domains present on both proteins (2). Thus different PDZ domains of PSD-95 might be specialized for distinct functions (3, 4). PSD95 participates in synaptic targeting of AMPA receptors through an indirect manner involving Stargazin and related transmembrane AMPA receptor regulatory proteins (TARPs) (5). The protein is implicated in experience dependent plasticity and plays an indispensable role in learning (6). Mutations in PSD95 are associated with autism (7).Synonyms: DLGH4, Disks large homolog 4, PSD-95, Postsynaptic density protein 95, SAP-90, SAP90, Synapse-associated protein 90
Gen-ID 29495
UniProt P31016
Pathways Regulation of Muscle Cell Differentiation, Synaptic Membrane, Skeletal Muscle Fiber Development, Asymmetric Protein Localization, Regulation of long-term Neuronal Synaptic Plasticity

Anwendungsinformationen

Produktdetails Antigendetails Handhabung Bilder zurück nach oben
Applikations-hinweise Western blot: 1: 250. Immunocytochemistry. Immunoflourescence. Immunohistochemistry on frozen sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails Antigendetails Anwendungsinformationen Bilder zurück nach oben
Konzentration 1.0 mg/mL
Buffer PBS pH 7.4, in 0.09 % azide in 50 % glycerol
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung 4 °C/-20 °C
Informationen zur Lagerung Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer. Avoidrepeated freezing and thawing.
Shelf life: one year from despatch.
Haltbarkeit 12 months