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anti-Human BHLHE41 Antikörper:
anti-Mouse (Murine) BHLHE41 Antikörper:
anti-Rat (Rattus) BHLHE41 Antikörper:
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Human Polyclonal BHLHE41 Primary Antibody für IHC, IHC (p) - ABIN446884
Inaguma, Riku, Hashimoto, Murakami, Saga, Ikeda, Kasai: GLI1 interferes with the DNA mismatch repair system in pancreatic cancer through BHLHE41-mediated suppression of MLH1. in Cancer research 2013
Show all 2 Pubmed References
Human Monoclonal BHLHE41 Primary Antibody für IF, ELISA - ABIN528943
Lecomte, Meugnier, Euthine, Durand, Freyssenet, Nemoz, Rome, Vidal, Lefai: A new role for sterol regulatory element binding protein 1 transcription factors in the regulation of muscle mass and muscle cell differentiation. in Molecular and cellular biology 2010
Cow (Bovine) Polyclonal BHLHE41 Primary Antibody für WB - ABIN2778014
Blondelle, Shapiro, Domenighetti, Lange: Cullin E3 Ligase Activity Is Required for Myoblast Differentiation. in Journal of molecular biology 2017
It has been concluded that the renal cell carcinoma (zeige MOK Antikörper) risk allele at 12p12.1 maps to rs7132434, a functional variant in an enhancer that upregulates BHLHE41 expression which, in turn, induces IL-11 (zeige IL11 Antikörper), a member of the IL-6 (zeige IL6 Antikörper) cytokine family.
The renal cell cancers associated polymorphic HIF-binding site at chromosome 12p12.1 regulates BHLHE41 expression.
Findings suggest that basic helix-loop-helix family, member e41 protein (DEC2) suppresses cell cycle progression of the mesenchymal cells.
DEC1 (zeige BHLHE40 Antikörper), at least partly, exerted a pro-apoptotic effect, whereas DEC2 exerted an anti-apoptotic effect in paclitaxel-induced apoptosis of human prostate cancer cells.
the present study indicated that SHARP1 acts as a tumor suppressor in thyroid cancer and that its downregulation may contribute to the proliferation, migration and invasion of thyroid cancer cells through mechanisms possibly involving HIF1alpha (zeige HIF1A Antikörper)
Study found that DEC2 was a direct target of miR (zeige MLXIP Antikörper)-138.
DEC2 is aberrantly expressed in rheumatoid arthritis tissue, it is induced by TNFalpha (zeige TNF Antikörper) and not only affects the expression of genes belonging to molecular clock but also significantly impacts on the expression of IL-1beta (zeige IL1B Antikörper) as well as other inflammatory genes.
BHLHE40 (zeige BHLHE40 Antikörper)/41 are promising markers to predict the aggressiveness of each Endometrial Neoplasm case and that molecular targeting strategies involving BHLHE40 (zeige BHLHE40 Antikörper)/41 and SP1 (zeige PSG1 Antikörper) may effectively regulate Endometrial Neoplasm progression.
DEC2 facilitates HIF-1alpha (zeige HIF1A Antikörper) stabilization and promotes HIF-1 (zeige HIF1A Antikörper) activation in osteosarcoma.
DEC2 participates in hypoxia-induced cell proliferation by functioning as a target gene of the PI3K (zeige PIK3CA Antikörper)/Akt (zeige AKT1 Antikörper) signaling pathway and regulating the expression of c-Myc (zeige MYC Antikörper).
Bhlhe41 directly repressed the expression of cell-cycle regulators and inhibitors of BCR (zeige BCR Antikörper) signaling while enabling pro-survival cytokine signaling. Thus, Bhlhe41 controls the development, BCR (zeige BCR Antikörper) repertoire and self-renewal of B-1a cells.
Data show that the bHLH transcription factors SHARP1 and SHARP2 are involved in cognitive processing by controlling insulin-like growth factor II (Igf2) expression and associated signaling cascades.
abnormal sleep and certain (endo)phenotypes of psychiatric diseases may be caused by common mechanisms involving components of the molecular clock including SHARP1 and SHARP2 (zeige BHLHE40 Antikörper).
SENP1 (zeige SENP1 Antikörper) enhances adipogenesis through de-SUMOylation of Sharp-1, which then releases Sharp-1 repression of PPARgamma (zeige PPARG Antikörper) expression and adipocyte differentiation. These results reveal SENP1 (zeige SENP1 Antikörper) as a novel regulator in adipogenesis.
DEC2 regulates cellular function by modulating the expression of Twist1 (zeige TWIST1 Antikörper)
These results demonstrate that Sharp-1 regulates muscle regenerative capacity, at least in part, by modulation of TGF-beta (zeige TGFB1 Antikörper) signaling
Data show that G9a (zeige EHMT2 Antikörper), a lysine methyltransferase, is involved in Sharp-1-mediated inhibition of muscle differentiation.
Interactions of Per1 (zeige PER1 Antikörper)/2 and Dec2 in the regulation of period, phase, and rhythm sustainment are cell-type specific.
RORalpha suppresses adipogenic differentiation at a later stage of differentiation by RORE-mediated stimulation of Dec1 (zeige BHLHE40 Antikörper) and Dec2 expression.
Results suggest a partially redundant and bidirectional regulatory function for Dec1/2 genes in transcriptional translational feedback loops and conservation of Per1-Dec synergism between vertebrate and invertebrate clocks.
This gene encodes a transcription factor that belongs to the Hairy/Enhancer of Split subfamily of basic helix-loop-helix factors. The encoded protein functions as a transcriptional repressor and as a regulator of molecular clock. Defects in this gene are associated with the short sleep phenotype.
basic helix-loop-helix domain containing, class B, 3
, basic helix-loop-helix family, member e41
, class E basic helix-loop-helix protein 41
, differentially expressed in chondrocytes protein 2
, enhancer-of-split and hairy-related protein 1
, bHLH transcriptional factor Dec2
, basic helix-loop-helix domain containing, class B3
, class B basic helix-loop-helix protein 3