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Human ANGPTL6 Protein expressed in HEK-293 Cells - ABIN1344366
Broxmeyer, Srour, Cooper, Wallace, Hangoc, Youn: Angiopoietin-like-2 and -3 act through their coiled-coil domains to enhance survival and replating capacity of human cord blood hematopoietic progenitors. in Blood cells, molecules & diseases 2012
This gene is a member of the cytidine deaminase gene family. It is one of seven related genes or pseudogenes found in a cluster, thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1. The protein encoded by this gene lacks the zinc binding activity of other family members. The protein plays a role in immunity, by restricting transmission of foreign DNA such as viruses. One mechanism of foreign DNA restriction is deamination of foreign double-stranded DNA cytidines to uridines, which leads to DNA degradation. However, other mechanisms are also thought to be involved, as anti-viral effect is not dependent on deaminase activity. Two transcript variants encoding different isoforms have been found for this gene.
angiopoietin-like protein 6
, angiopoietin-related growth factor
, angiopoietin-related protein 5
, angiopoietin-related protein 6
, Angiopoietin-related growth factor
, angiopoietin-like protein 6 alpha form
, angiopoietin-like protein 6 beta form
, angiopoietin-like 6
, angiopoietin-related protein 6-like
, actin-like protein 3
, actin-related protein 3
, actin-related protein 3 homolog (yest)
, ARP3 actin-related protein 3 homolog