TNF alpha Protein
(2 Referenzen)-
- Target Alle TNF alpha Proteine anzeigen
- TNF alpha (Tumor Necrosis Factor alpha (TNF alpha))
- Biologische Aktivität
- Active
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Spezies
- Human
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Quelle
- Yeast (Pichia pastoris)
- Sequenz
- VRSSSRTPSD KPVAHVVANP QAEGQLQWLN RRANALLANG VELRDNQLVV PSEGLYLIYS QVLFKGQGCP STHVLLTHTI SRIAVSYQTK VNLLSAIKSP CQRETPEGAE AKPWYEPIYL GGVFQLEKGD RLSAEINRPD YLDFAESGQV YFGIIA
- Produktmerkmale
- Plate 3*104 cell per well in 96-well plates in RPMI 1640 medium with 10%FBS for 24 h. Sub confluent cells were starved 4 h in RPMI 1640 medium with 2%FBS. Standard and Sample 2-human TNF- alpha were added and cell viability measured 24 h later by addition of CellTiter 96® AQueous Non-Radioactive Cell Proliferation Assay reagent (MTS). The ED50 for this effect is typically 0.02-0.08ng/ml.
- Reinheit
- > 97 % by SDS-PAGE.
- Endotoxin-Niveau
- level is less than 0.1 ng per myg (1EU/myg) of TNF-alpha
- Top Product
- Discover our top product TNF alpha Protein
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Tumor Necrosis Factor alpha (TNF alpha) (AA 77-233) protein (His-Avi Tag,Biotin)
TNF alpha Spezies: Human Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Tumor Necrosis Factor alpha (TNF alpha) (AA 77-233) protein (His-Avi Tag)TNF alpha Spezies: Human Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Tumor Necrosis Factor alpha (TNF alpha) (AA 77-233) protein (His tag)TNF alpha Spezies: Human Wirt: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Tumor Necrosis Factor alpha (TNF alpha) (AA 77-233) (Active) proteinHPLC verified TNF alpha Spezies: Human Wirt: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Tumor Necrosis Factor alpha (TNF alpha) (AA 77-233) (Active) protein (Biotin)TNF alpha Spezies: Human Wirt: HEK-293 Cells Recombinant >95 % as determined by reduced SDS-PAGE. Active
Tumor Necrosis Factor alpha (TNF alpha) (AA 77-233) (Active) protein (His tag,AVI tag,Biotin)TNF alpha Spezies: Human Wirt: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Tumor Necrosis Factor alpha (TNF alpha) (Active) proteinTNF alpha Spezies: Kaninchen Wirt: Escherichia coli (E. coli) Recombinant > 95 % as determined by reducing SDS-PAGE. Active
Tumor Necrosis Factor alpha (TNF alpha) (Active) proteinTNF alpha Spezies: Maus Wirt: Escherichia coli (E. coli) Recombinant > 95 % as determined by SDS-PAGE Active
Tumor Necrosis Factor alpha (TNF alpha) (AA 1-233) protein (GST tag)TNF alpha Spezies: Human Wirt: Wheat germ Recombinant WB, ELISA, AA, AP
Tumor Necrosis Factor alpha (TNF alpha) (AA 1-235) protein (His tag)custom-made TNF alpha Spezies: Maus Wirt: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Lagerung
- -20 °C
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: "Glycosylation profiling of therapeutic antibodies in serum samples using a microfluidic CD platform and MALDI-MS." in: Journal of the American Society for Mass Spectrometry, Vol. 24, Issue 7, pp. 1053-63, (2013) (PubMed).
: "CNK1 promotes invasion of cancer cells through NF-kappaB-dependent signaling." in: Molecular cancer research : MCR, Vol. 8, Issue 3, pp. 395-406, (2010) (PubMed).
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: "Glycosylation profiling of therapeutic antibodies in serum samples using a microfluidic CD platform and MALDI-MS." in: Journal of the American Society for Mass Spectrometry, Vol. 24, Issue 7, pp. 1053-63, (2013) (PubMed).
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- Target
- TNF alpha (Tumor Necrosis Factor alpha (TNF alpha))
- Andere Bezeichnung
- Tumor Necrosis Factor-alpha (TNF-alpha) (TNF alpha Produkte)
- Hintergrund
- TNF-alpha plays a major role in growth regulation, differentiation, inflammation, viral replication, tumorigenesis, and autoimmune diseases. Besides inducing hemorrhagic necrosis of tumors, TNF has been found to be involved in tumorigenesis, tumor metastasis, viral replication, septic shock, fever, inflammation, and autoimmune diseases including Crohn's disease, and rheumatoid arthritis as well as graft-versus-host disease. TNF alpha-1a is a potent lymphoid factor that exerts cytotoxic effects on a wide range of tumor cells and certain other target cells. Synonym: TNF-alpha. Formulation: Lyophilized from a 0.2 mym filtered solution in PBS.
- Pathways
- NF-kappaB Signalweg, Apoptose, Caspase Kaskade in der Apoptose, TLR Signalweg, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Inflammasome
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