CCL28 Protein

Produktnummer ABIN988143

Produktdetails

Target: CCL28 (Chemokine (C-C Motif) Ligand 28 (CCL28))

Biologische Aktivität: Active

Spezies: Maus

Quelle: Escherichia coli (E. coli)

Sequenz: SEAILPMASS CCTEVSHHVS GRLLERVSSC SIQRADGDCD LAAVILHVKR RRICISPHNR TLKQWMRASE VKKNGRENVC SGKKQPSRKD RKGHTTRKHR TRGTHRHEAS

Produktmerkmale: Fully biologically active when compared to standard. The ED50 determined by a chemotaxis bioassay using murine lymphocytes is less than 10 ng/ml, corresponding to a specific activity of >, 1.0 × 105 IU/mg.

Reinheit: > 97 % by SDS-PAGE and HPLC analyses.

Endotoxin-Niveau: Level Less than 1EU/µg of rMuMEC/CCL28 as determined by LAL method

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/ml. Stock solutions should be apportioned into working aliquots and stored at < -20 °C. Further dilutions should be made in appropriate buffered solutions.

Lagerung: 4 °C

Antigendetails

Target: CCL28 (Chemokine (C-C Motif) Ligand 28 (CCL28))

Andere Bezeichnung: MEC/CCL28 (CCL28 Produkte)

Synonyme: Scya28 Protein, CCL28 Protein, ccl28 Protein, nrpb Protein, enc-1 Protein, pig10 Protein, Encr-3 Protein, klhl35 Protein, Xencr-3 Protein, tp53i10 Protein, LOC100303767 Protein, CCK1 Protein, MEC Protein, SCYA28 Protein, C-C motif chemokine ligand 28 Protein, ectodermal-neural cortex 1 (with BTB domain) Protein, C-C motif chemokine 28 Protein, chemokine (C-C motif) ligand 28 Protein, Ccl28 Protein, CCL28 Protein, ccl28 Protein, enc1 Protein, LOC100303767 Protein

Hintergrund: Mouse CCL28 (CC chemokine ligand 28) is a novel CC chemokine cloned from a Rag1 mouse kidney cDNA library. Human and mouse CCL28 are highly conserved, sharing 83% aa identity in their mature regions. Among CC chemokines, CCL28 shares the most homology with CCL27/CTACK. The mouse CCL28 gene has been mapped to the distal region of chromosome 13. Mouse CCL28 is produced by epithelial cells. Based on Northern blot analysis, it is mainly expressed in testes, kidney and brain. The receptor for CCL28 has been identified as the CCR10 (GPR2 orphan receptor) which is also the receptor for CCL27/CTACK. Synonym: MEC/CCL28, Mouse. Formulation: Lyophilized from a 0.2µm filtered concentrated solution in 20mM PB, pH 7.4,150mM NaCl.

Molekulargewicht: 12.6 kDa, a single, non-glycosylated polypeptide chain containing 111 amino acids.