COL18A1 Protein
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- Target Alle COL18A1 Proteine anzeigen
- COL18A1 (Collagen, Type XVIII, alpha 1 (COL18A1))
- Protein-Typ
- Recombinant
- Biologische Aktivität
- Active
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Spezies
- Human
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Quelle
- Yeast (Pichia pastoris)
- Produktmerkmale
- Determined by Endothelial Cell Tube Formation. The cells treated with 10myg/ml Endostatin showed significant anti-angiogenesis effect.
- Reinheit
- > 97 % by SDS-PAGE
- Endotoxin-Niveau
- level is less than 0.1 ng per myg (1EU/myg) of Endostatin
- Top Product
- Discover our top product COL18A1 Protein
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Lagerung
- -20 °C
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- Target
- COL18A1 (Collagen, Type XVIII, alpha 1 (COL18A1))
- Andere Bezeichnung
- Endostatin (COL18A1 Produkte)
- Synonyme
- KNO Protein, KNO1 Protein, KS Protein, cb371 Protein, cb529 Protein, fc96d06 Protein, sb:cb529 Protein, wu:fb47h10 Protein, wu:fb77g12 Protein, wu:fc50f04 Protein, wu:fc96d06 Protein, wu:fk02h12 Protein, kno Protein, kno1 Protein, collagen type XVIII alpha 1 chain Protein, collagen type XVIII alpha 1 chain a Protein, collagen, type XVIII, alpha 1 Protein, collagen type XVIII alpha 1 Protein, COL18A1 Protein, col18a1a Protein, Col18a1 Protein, col18a1 Protein
- Substanzklasse
- Chemical
- Hintergrund
- Endostatin is a cleaved product of the carboxyl-terminal domain of collagen XVIII. It functions as an anti-angiogenic cytokine that is expressed in various organs especially with high levels in liver, lung, and kidney. Endostatin inhibits angiogenesis by blocking the pro-angiogenic activities of VEGF and FGF-basic. Recombinant Endostatin expressed in yeast, whichcauses G1 arrest of endothelial cells. Endostatin treatment results in apoptosis of HUVE and HMVE cells. Recombinant human Endostatin is a 20.2 kDa protein consisting of 184 amino acid residues. Synonym: Endostatin 3 3 . Formulation: The sterile filtered solution was lyophilized with 17 mM citric-phosphate buffer, pH 6.2. .
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