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COL18A1 Protein

COL18A1 Spezies: Human Wirt: Yeast (Pichia pastoris) Recombinant > 97 % by SDS-PAGE Active
Produktnummer ABIN987805
  • Target Alle COL18A1 Proteine anzeigen
    COL18A1 (Collagen, Type XVIII, alpha 1 (COL18A1))
    Protein-Typ
    Recombinant
    Biologische Aktivität
    Active
    Spezies
    • 6
    • 4
    • 2
    Human
    Quelle
    • 7
    • 2
    • 1
    • 1
    • 1
    Yeast (Pichia pastoris)
    Produktmerkmale
    Determined by Endothelial Cell Tube Formation. The cells treated with 10myg/ml Endostatin showed significant anti-angiogenesis effect.
    Reinheit
    > 97 % by SDS-PAGE
    Endotoxin-Niveau
    level is less than 0.1 ng per myg (1EU/myg) of Endostatin
    Top Product
    Discover our top product COL18A1 Protein
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Lagerung
    -20 °C
  • Target
    COL18A1 (Collagen, Type XVIII, alpha 1 (COL18A1))
    Andere Bezeichnung
    Endostatin (COL18A1 Produkte)
    Synonyme
    KNO Protein, KNO1 Protein, KS Protein, cb371 Protein, cb529 Protein, fc96d06 Protein, sb:cb529 Protein, wu:fb47h10 Protein, wu:fb77g12 Protein, wu:fc50f04 Protein, wu:fc96d06 Protein, wu:fk02h12 Protein, kno Protein, kno1 Protein, collagen type XVIII alpha 1 chain Protein, collagen type XVIII alpha 1 chain a Protein, collagen, type XVIII, alpha 1 Protein, collagen type XVIII alpha 1 Protein, COL18A1 Protein, col18a1a Protein, Col18a1 Protein, col18a1 Protein
    Substanzklasse
    Chemical
    Hintergrund
    Endostatin is a cleaved product of the carboxyl-terminal domain of collagen XVIII. It functions as an anti-angiogenic cytokine that is expressed in various organs especially with high levels in liver, lung, and kidney. Endostatin inhibits angiogenesis by blocking the pro-angiogenic activities of VEGF and FGF-basic. Recombinant Endostatin expressed in yeast, whichcauses G1 arrest of endothelial cells. Endostatin treatment results in apoptosis of HUVE and HMVE cells. Recombinant human Endostatin is a 20.2 kDa protein consisting of 184 amino acid residues. Synonym: Endostatin 3 3 . Formulation: The sterile filtered solution was lyophilized with 17 mM citric-phosphate buffer, pH 6.2. .
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