Troponin I Protein (TNNI)

Produktnummer ABIN935834

Produktdetails

Target: Troponin I (TNNI)

Protein-Typ: Native

Spezies: Human

Quelle: Human

Produktmerkmale: Purified native Human Troponin I protein (Cardiac)
Protein Source: Human cardiac tissue

Anwendungsinformationen

Applikationshinweise: Each Investigator should determine their own optimal working dilution for specific applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Supplied frozen in 25 mM TRIS buffer, pH 7.5, with 155 M NaCl, and 0.09 % NaN3. 0.1-5 % of the total protein is Troponin I.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot and store at -20 °C.

Referenzen

Mulvaney, Cole, Kniller, Malito, Tamanaha, Rife, Stanton, Whitman: "Rapid, femtomolar bioassays in complex matrices combining microfluidics and magnetoelectronics." in: Biosensors & bioelectronics, Vol. 23, Issue 2, pp. 191-200, (2007) (PubMed).

Antigendetails

Target: Troponin I (TNNI)

Andere Bezeichnung: Troponin I (TNNI Produkte)

Synonyme: CG7178 Protein, DROTROPONI Protein, DmTpnI Protein, Dmel\\CG7178 Protein, HDP Protein, HL-I Protein, HL08042 Protein, HLI Protein, Tn I Protein, TnI Protein, TpnI Protein, WupA Protein, hdp Protein, hdp2 Protein, wup-A Protein, tni Protein, wings up A Protein, troponin I Protein, putative troponin I Protein, wupA Protein, tni Protein, LOC5574015 Protein, Smp_059170.1 Protein

Hintergrund: Troponin I is a part of the troponin complex. It binds to actin in thin myofilaments to hold the actin-tropomyosin complex in place. Because of it myosin cannot bind actin in relaxed muscle. When calcium binds to the Troponin C it causes conformational changes which lead to dislocation of troponin I and finally tropomyosin leaves the binding site for myosin on actin leading to contraction of muscle.
Description: Human cardiac tissue.

Molekulargewicht: 100 kDa