Neuroserpin Protein
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- Target Alle Neuroserpin (SERPINI1) Proteine anzeigen
- Neuroserpin (SERPINI1) (serpin Peptidase Inhibitor, Clade I (neuroserpin), Member 1 (SERPINI1))
- Protein-Typ
- Recombinant
- Biologische Aktivität
- Active
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Spezies
- Human
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Quelle
- Escherichia coli (E. coli)
- Sequenz
- MTGATFPEEA IADLSVNMYN RLRATGEDEN ILFSPLSIAL AMGMMELGAQ GSTQKEIRHS MGYDSLKNGE EFSFLKEFSN MVTAKESQYV MKIANSLFVQ NGFHVNEEFL QMMKKYFNAA VNHVDFSQNV AVANYINKWV ENNTNNLVKD LVSPRDFDAA TYLALINAVY FKGNWKSQFR PENTRTFSFT KDDESEVQIP MMYQQGEFYY GEFSDGSNEA GGIYQVLEIP YEGDEISMML VLSRQEVPLA TLEPLVKAQL VEEWANSVKK QKVEVYLPRF TVEQEIDLKD VLKALGITEI FIKDANLTGL SDNKEIFLSK AIHKSFLEVN EEGSEAAAVS GMIAISRMAV LYPQVIVDHP FFFLIRNRRT GTILFMGRVM HPETMNTSGH DFEEL
- Produktmerkmale
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Purified recombinant Human Neuroserpin protein
Expression System: E.coli
Bioactivity: Determined by the dose-dependent stimulation of the proliferation of rat C6 cells using a concentration range of 0.3-0.6 µg/mL. - Reinheit
- > 96 % pure
- Endotoxin-Niveau
- < 0.1 ng per µg (1 EU/µg).
- Top Product
- Discover our top product SERPINI1 Protein
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serpin Peptidase Inhibitor, Clade I (neuroserpin), Member 1 (SERPINI1) (AA 17-410) protein (GST tag)
SERPINI1 Spezies: Human Wirt: Wheat germ Recombinant WB, ELISA, AP, AA
serpin Peptidase Inhibitor, Clade I (neuroserpin), Member 1 (SERPINI1) protein (His tag)SERPINI1 Spezies: Maus Wirt: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE
serpin Peptidase Inhibitor, Clade I (neuroserpin), Member 1 (SERPINI1) (AA 17-410) protein (His tag)Crystallography grade SERPINI1 Spezies: Maus Wirt: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, ELISA, SDS, Crys
serpin Peptidase Inhibitor, Clade I (neuroserpin), Member 1 (SERPINI1) (Transcript Variant 1) (Active) proteinSERPINI1 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 95 % as determined by SDS-PAGE and Coomassie blue staining Func, AbP, PI, STD Active
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- Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Buffer
- Supplied as a lyophilized powder.
- Handhabung
- Avoid repeated freeze/thaw cycles.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.
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- Target
- Neuroserpin (SERPINI1) (serpin Peptidase Inhibitor, Clade I (neuroserpin), Member 1 (SERPINI1))
- Andere Bezeichnung
- Neuroserpin (SERPINI1 Produkte)
- Synonyme
- PI12 Protein, neuroserpin Protein, AI837402 Protein, Ns Protein, PI-12 Protein, Spi17 Protein, CG9453 Protein, Dmel\\CG9453 Protein, Serp2 Protein, Sp4 Protein, Spn4 Protein, Spn4A Protein, dSerp2 Protein, sp4 Protein, spn4 Protein, raPIT5a Protein, SERPINI1 Protein, pi12 Protein, serpini1l Protein, si:ch211-167c22.4 Protein, serpin family I member 1 Protein, serine (or cysteine) peptidase inhibitor, clade I, member 1 Protein, Serpin 42Da Protein, serpin peptidase inhibitor, clade I (neuroserpin), member 1 Protein, serpin family I member 1 L homeolog Protein, SERPINI1 Protein, Serpini1 Protein, Spn42Da Protein, serpini1 Protein, serpini1.L Protein
- Hintergrund
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Neuroserpin is an inhibitory serpin that is expressed predominantly in central nervous system. Although the physiological target of neuroserpin is still unclear, cumulative evidence suggest that it plays an important role in controlling proteolytic degradation of extracellular matrix (ECM) during synaptogenesis and the subsequent development of neuronal plasticity. In the adult brain, neuroserpin is secreted from the growth cones of neurons in areas where synaptic changes are associated with learning and memory, i.e. cerebral cortex, hippocampus, and amygdala.
Alternative Names: Serpin I1 protein, Protease inhibitor 12 protein - Molekulargewicht
- 44.6 kDa
- Pathways
- Regulation of Hormone Metabolic Process
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