HIF1AN Protein (AA 1-349)

Produktnummer ABIN935007

Produktdetails

Target: HIF1AN (Hypoxia Inducible Factor 1, alpha Subunit Inhibitor (HIF1AN))

Protein-Typ: Recombinant

Proteineigenschaft: AA 1-349

Spezies: Human

Quelle: Escherichia coli (E. coli)

Applikation: SDS-PAGE (SDS)

Sequenz: MAATAAEAVA SGSGEPREEA GALGPAWDES QLRSYSFPTR PIPRLSQSDP RAEELIENEE PVVLTDTNLV YPALKWDLEY LQENIGNGDF SVYSASTHKF LYYDEKKMAN FQNFKPRSNR EEMKFHEFVE KLQDIQQRGG EERLYLQQTL NDTVGRKIVM DFLGFNWNWI NKQQGKRGWG QLTSNLLLIG MEGNVTPAHY DEQQNFFAQI KGYKRCILFP PDQFECLYPY PVHHPCDRQS QVDFDNPDYE RFPNFQNVVG YETVVGPGDV LYIPMYWWHH IESLLNGGIT ITVNFWYKGA PTPKRIEYPL KAHQKVAIMR NIEKMLGEAL GNPQEVGPLL NTMIKGRYN

Produktmerkmale: Purified recombinant Human HIF1 AN protein
Expression System: E.coli
Molecular weight on SDS-PAGE will appear higher.

Reinheit: > 90 % pure

Anwendungsinformationen

Applikationshinweise: HIF1AN protein has been used in SDS PAGE and may be suitable for use in other assays to be determined by the end user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Supplied as a liquid in 20 mM Tris-HCl buffer, pH 8.0.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: RT/-20 °C

Informationen zur Lagerung: Store at 4 °C for short term storage (1/2 weeks). Aliquot and store at -20 °C or - 70 °C for long term storage.

Antigendetails

Target: HIF1AN (Hypoxia Inducible Factor 1, alpha Subunit Inhibitor (HIF1AN))

Andere Bezeichnung: HIF1AN (HIF1AN Produkte)

Synonyme: FIH1 Protein, 2310046M24Rik Protein, A830014H24Rik Protein, cb728 Protein, id:ibd5139 Protein, hypoxia inducible factor 1 alpha subunit inhibitor Protein, hypoxia-inducible factor 1, alpha subunit inhibitor Protein, hypoxia inducible factor 1, alpha subunit inhibitor Protein, hypoxia-inducible factor 1, alpha subunit inhibitor S homeolog Protein, HIF1AN Protein, Hif1an Protein, hif1an Protein, hif1an.S Protein

Hintergrund: Hypoxia-inducible factor 1, alpha subunit inhibitor (HIF1AN), a member of the Fe2+ and 2-oxoglutarate-dependent dioxygenase superfamily, is a protein that hydoxylates a specific asparagine residue (Asn-803) within the HIF1alpha C-terminal transactivation domain. In normoxia, the HIF1AN-mediated hydroxylation of the HIF1alpha transactivation domain results in blockage of the HIF1alpha-p300/CBP interaction and represses transcriptional activity of HIF1alpha-targeted genes. Recombinant human HIF1AN protein was expressed in E. coli and purified by using conventional chromatography techniques.
Alternative Names: HIFAN 1, FIH 1 protein, DKFZp762F1811 protein, Hypoxia-inducible factor 1 protein, HIFAN-1, Hypoxia-inducible factor asparagine hydroxylase protein, Hypoxia inducible factor 1 alpha subunit inhibitor protein, alpha subunit inhibitor Hypoxia inducible factor asparagine hydroxylase protein, Factor inhibiting HIF1 protein, Peptide aspartate beta dioxygenase protein, HIFAN-1 protein, HIFAN 1 protein, FLJ22027 protein, FLJ20615 protein, Hypoxia inducible factor 1 alpha inhibitor protein, FIH1 protein, Factor inhibiting HIF-1 protein, Hypoxia-Inducible Factor-1 Alpha Inhibitor, HIF1AN

Molekulargewicht: 40.2 kDa (349 AA)

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development