UBE2L3 Protein (His tag)

Produktnummer ABIN7533751

Produktdetails

Target: UBE2L3 (Ubiquitin-Conjugating Enzyme E2L 3 (UBE2L3))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses UBE2L3 Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human UBE2L3 Protein

Sequenz: MAASRRLMKE LEEIRKCGMK NFRNIQVDEA NLLTWQGLIV PDNPPYDKGA FRIEINFPAE YPFKPPKITF KTKIYHPNID EKGQVCLPVI SAENWKPATK TDQVIQSLIA LVNDPQPEHP LRADLAEEYS KDRKKFCKNA EEFTKKYGEK RPVD

Spezifität: Met1-Asp154

Reinheit: > 95 % by SDS-PAGE.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.542 mg/mL

Buffer: Supplied in 50 mM HEPES,200 mM NaCl,10 % glycerol,1 mM TCEP, pH 7.0

Lagerung: -80 °C

Informationen zur Lagerung: This product is stable at ≤ -70° C for up to 1 year from the date of receipt.
For optimal storage, aliquot into smaller quantities after centrifugation and store at recommended temperature.

Antigendetails

Target: UBE2L3 (Ubiquitin-Conjugating Enzyme E2L 3 (UBE2L3))

Andere Bezeichnung: UBE2L3 (UBE2L3 Produkte)

Synonyme: E2-F1 Protein, L-UBC Protein, UBCH7 Protein, UbcM4 Protein, C79827 Protein, Ubce7 Protein, ube2l3 Protein, wu:fc22h11 Protein, zgc:86727 Protein, UBE2L3 Protein, ube2l3l Protein, wu:fb38h03 Protein, ubiquitin conjugating enzyme E2 L3 Protein, ubiquitin-conjugating enzyme E2L 3 Protein, ubiquitin-conjugating enzyme E2L 3a Protein, ubiquitin conjugating enzyme E2 L3 S homeolog Protein, ubiquitin-conjugating enzyme E2L 3b Protein, UBE2L3 Protein, Ube2l3 Protein, ube2l3a Protein, ube2l3.S Protein, ube2l3b Protein

Hintergrund:

Description: Ubiquitin-conjugating Enzyme E2L 3 (UBE2L3),also known as Ubiquitin-conjugating Enzyme H7 (UbcH7), is a member of the Ubiquitin-conjugating (E2) enzyme family (1). The human UbcH7 protein shares 100 % amino acid (aa) sequence identity with the mouse and rat orthologs. UBE2L3 is catalytically active with HECT and RBR domain-containing families of Ubiquitin ligases (E3s). UBE2L3 localizes to both the nucleus and cytoplasm in human cells. UBE2L3 depletion results in an extended S phase and a reduced rate of proliferation, suggesting that it may play a role in the cell cycle. In humans, single nucleotide polymorphisms in UBE2L3 are associated with systemic lupus erythematosus and Crohn's disease, suggesting that UbcH7 is important for proper immune system function.

Name: UBE2L3,E2-F1,L-UBC,UBCH7,UbcM4,Ube2L3 / UBCH7

Gen-ID: 7332

UniProt: P68036