Olfactomedin 4 Protein (OLFM4) (His tag)

Produktnummer ABIN7520372

Produktdetails

Target: Olfactomedin 4 (OLFM4)

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses Olfactomedin 4 Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant human Olfactomedin-4/OLFM4 Protein

Sequenz: DLGDVGPPIP SPGFSSFPGV DSSSSFSSSS RSGSSSSRSL GSGGSVSQLF SNFTGSVDDR GTCQCSVSLP DTTFPVDRVE RLEFTAHVLS QKFEKELSKV REYVQLISVY EKKLLNLTVR IDIMEKDTIS YTELDFELIK VEVKEMEKLV IQLKESFGGS SEIVDQLEVE IRNMTLLVEK LETLDKNNVL AIRREIVALK TKLKECEASK DQNTPVVHPP PTPGSCGHGG VVNISKPSVV QLNWRGFSYL YGAWGRDYSP QHPNKGLYWV APLNTDGRLL EYYRLYNTLD DLLLYINARE LRITYGQGSG TAVYNNNMYV NMYNTGNIAR VNLTTNTIAV TQTLPNAAYN NRFSYANVAW QDIDFAVDEN GLWVIYSTEA STGNMVISKL NDTTLQVLNT WYTKQYKPSA SNAFMVCGVL YATRTMNTRT EEIFYYYDTN TGKEGKLDIV MHKMQEKVQS INYNPFDQKL YVYNDGYLLN YDLSVLQKPQ

Spezifität: Asp21-Gln510

Sterilität: 0.22 μm filtered

Endotoxin-Niveau: <1EU/μg

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.

Konzentration: 0.43 mg/mL

Buffer: Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Store the lyophilized protein at -20°C to -80°C for 12 months.|After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.

Antigendetails

Target: Olfactomedin 4 (OLFM4)

Andere Bezeichnung: Olfactomedin-4/OLFM4 (OLFM4 Produkte)

Synonyme: tiarin Protein, GC1 Protein, GW112 Protein, OLM4 Protein, OlfD Protein, UNQ362 Protein, bA209J19.1 Protein, hGC-1 Protein, hOLfD Protein, Gm296 Protein, Gm913 Protein, pPD4 Protein, olfactomedin-4 Protein, olfactomedin 4 L homeolog Protein, olfactomedin 4 Protein, olfactomedin-4-like Protein, olfm4.L Protein, OLFM4 Protein, olfm4 Protein, LOC100225360 Protein, Olfm4 Protein

Hintergrund:

Description: Olfactomedin-4 (OLFM4), previously called GC-1 (G-CSF stimulated clone-1) is an secreted glycoprotein that is a member of the Olfactomedin/Noelin family of protein . It is expressed in epithelial cells of the prostate, small intestine, colon, bone marrow, and in several cancers , and is up-regulated in epithelial cells during inflammation . Mature OLFM4 is a 490 amino acid (aa) protein that is secreted mainly in a polymeric form which is held together by disulfide bonds and carbohydrate interactions . Mature human OLFM4 shares 71 % aa sequence identity with mature mouse and rat OLFM4. Olfactomedin-4 (OLFM4) interacts with cell surface lectins and cadherins, which helps cell adhesion and cell spreading of NIH3T3 and 293T/17 cells . OLFM4 plays a critical role in regulating progression of prostate cancer and is also novel biomarker for triple-negative breast cancer .

Name: GC1, OLM4, OlfD, GW112, hGC-1, hOLfD, UNQ362, bA209J19.1

Gen-ID: 10562

UniProt: Q6UX06