MITF Protein (rFc Tag)

Produktnummer ABIN7535744

Produktdetails

Target: MITF (Microphthalmia-Associated Transcription Factor (MITF))

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses MITF Protein ist gelabelt mit rFc Tag.

Verwendungszweck: Recombinant Human MITF Protein

Sequenz: HGLSLIPSTG LCSPDLVNRI IKQEPVLENC SQDLLQHHAD LTCTTTLDLT DGTITFNNNL GTGTEANQAY SVPTKMGSKL EDILMDDTLS PVGVTDPLLS SVSPGASKTS SRRSSMSMEE TEHTC

Spezifität: His402-Cys526

Reinheit: > 95 % by SDS-PAGE.

Sterilität: 0.22 μm filtered

Endotoxin-Niveau: <0.1EU/μg

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.

Buffer: Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Store the lyophilized protein at -20°C to -80°C for 12 months.|After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.

Antigendetails

Target: MITF (Microphthalmia-Associated Transcription Factor (MITF))

Andere Bezeichnung: MITF (MITF Produkte)

Synonyme: MITF Protein, ws2a Protein, mitfa Protein, MITF-A Protein, LOC100313655 Protein, mitfb Protein, CMM8 Protein, MI Protein, WS2 Protein, WS2A Protein, bHLHe32 Protein, BCC2 Protein, Bhlhe32 Protein, Gsfbcc2 Protein, Vitiligo Protein, Wh Protein, bw Protein, mi Protein, vit Protein, MITF-H Protein, MITF-M Protein, CMI9 Protein, melanogenesis associated transcription factor Protein, microphthalmia-associated transcription factor Protein, microphthalmia-associated transcription factor S homeolog Protein, Microphthalmia Protein, MITF Protein, mitf Protein, LOC100313655 Protein, mitf.S Protein, LOC100534525 Protein, MICROP Protein, Mitf Protein

Hintergrund:

Description: Microphthalmia-associated transcription factor (MITF) is a member of the basic helix-loop-helix leucine zipper (bHLH-Zip) family and functions as the master regulator of the melanocytic lineage.MITF (Microphthalmia-associated transcription factor) is a lineage-specific transcription factor that plays a critical role in melanocyte homeostasis and whose deregulation has been shown to contribute to melanoma disease. Microphthalmia-associated transcription factor (MITF) is expressed in melanomas and has a critical role in melanocyte development and transformation. Because inhibition of MITF inhibits cell growth in melanoma, MITF is a potential therapeutic target molecule. Microphthalmia-associated transcription factor (MITF) regulates the transcription of its target genes by binding to their promoters. Microphthalmia-associated transcription factor (MITF) is a key regulator of differentiation of melanocytes and retinal pigment epithelial cells, but it also has functions in non-pigment cells.

Name: CMM8, COMMAD, MI, WS2, WS2A, bHLHe32,MITF,COMMAD,MI,WS2,WS2A,bHLHe32

Gen-ID: 4286

UniProt: O75030

Pathways: Chromatin Binding