Lipocalin 1 Protein (LCN1) (His tag)

Produktnummer ABIN7520291

Produktdetails

Target: Lipocalin 1 (LCN1)

Protein-Typ: Recombinant

Biologische Aktivität: Active

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses Lipocalin 1 Protein ist gelabelt mit His tag.

Verwendungszweck: Active Recombinant Human Lipocalin-1/LCN1 Protein

Sequenz: HHLLASDEEI QDVSGTWYLK AMTVDREFPE MNLESVTPMT LTTLEGGNLE AKVTMLISGR CQEVKAVLEK TDEPGKYTAD GGKHVAYIIR SHVKDHYIFY CEGELHGKPV RGVKLVGRDP KNNLEALEDF EKAAGARGLS TESILIPRQS ETCSPGSD

Spezifität: His19-Asp176

Reinheit: > 95 % by SDS-PAGE.

Sterilität: 0.22 μm filtered

Endotoxin-Niveau: <0.1EU/μg

Biological Activity Comment: Measured by its ability to inhibit active Cathepsin V cleavage of a fluorogenic peptide substrate Z-LR-AMC. The IC50 value is <2.94 nM.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.

Buffer: Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Store the lyophilized protein at -20°C to -80°C for 12 months.|After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.

Antigendetails

Target: Lipocalin 1 (LCN1)

Andere Bezeichnung: Lipocalin-1/LCN1 (LCN1 Produkte)

Synonyme: PMFA Protein, TLC Protein, TP Protein, VEGP Protein, VEG Protein, lipocalin 1 Protein, odorant binding protein 2B Protein, lipocalin-1 Protein, LCN1 Protein, OBP2B Protein, Lcn1 Protein, LOC103346758 Protein

Hintergrund:

Description: Lipocalin-1, also known as Von Ebner gland protein, VEG protein, Tear Prealbumin, VEGP, Tear lipocalin, and LCN1 is a secreted protein that belongs to the calycin superfamily and Lipocalin family. Human Lipocalin-1 / VEGP was originally described as a major protein of human tear fluid, which was thought to be tear specific. Lipocalin-1 / VEGP is identical to lingual von Ebner's gland protein and is also produced in the prostate, nasal mucosa, and tracheal mucosa. Homologous proteins have been found in the rat, pig, and probably dog and horse. Lipocalin-1 / VEGP is an unusual lipocalin member, because of its high promiscuity for relative insoluble lipids and binding characteristics that differ from other members. Lipocalin-1 / VEGP acts as the principal lipid-binding protein in tear fluid, a more general physiological function has to be proposed due to its wide distribution and properties. Lipocalin-1 / VEGP would be ideally suited for scavenging of lipophilic, potentially harmful substances and thus might act as a general protection factor of epithelia. Lipocalin-1 / LCN1 could play a role in taste reception. It could be necessary for the concentration and delivery of sapid molecules in the gustatory system. Lipocalin-1 / LCN1 can bind various ligands, with chemical structures ranging from lipids and retinoids to the macrocyclic antibiotic rifampicin and even to microbial siderophores. It exhibits an extremely wide ligand pocket.

Name: LCN1,PMFA,TLC,TP,VEGP

Gen-ID: 3933

UniProt: P31025