IL28A Protein (His tag)

Produktnummer ABIN7534305

Produktdetails

Target: IL28A (Interleukin 28A (Interferon, lambda 2) (IL28A))

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses IL28A Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human IFN-lambda 2/IL-28A Protein

Sequenz: VPVARLHGAL PDARGCHIAQ FKSLSPQELQ AFKRAKDALE ESLLLKDCRC HSRLFPRTWD LRQLQVRERP MALEAELALT LKVLEATADT DPALVDVLDQ PLHTLHHILS QFRACIQPQP TAGPRTRGRL HHWLYRLQEA PKKESPGCLE ASVTFNLFRL LTRDLNCVAS GDLCV

Spezifität: Val26-Val200

Reinheit: > 97 % by SDS-PAGE.

Sterilität: 0.22 μm filtered

Endotoxin-Niveau: < 0.1 EU/μg of the protein by LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.

Buffer: Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Store the lyophilized protein at -20°C to -80 °C for long term.
After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.

Antigendetails

Target: IL28A (Interleukin 28A (Interferon, lambda 2) (IL28A))

Andere Bezeichnung: IFN-lambda 2/IL-28A (IL28A Produkte)

Synonyme: EG330496 Protein, IL-28A Protein, Il28a Protein, IL28A Protein, interferon lambda 2 Protein, Ifnl2 Protein, IFNL2 Protein

Hintergrund:

Description: IL 28A (Interferon-lambda 2, IFN-lambda 2), IL-28B/IFN-lambda 3, and IL-29/IFN-lambda 1 are type III interferons which are distantly related to IL-10 family and type I IFN family cytokines . IL 28A ,interleukin 28B (IL28B), and interleukin 29 (IL29) are three closely related cytokine which are expression can be induced by viral infection.In the liver, the IL-28A induced Th1 cytokine response contributes to inflammation in T cell mediated hepatitis. IL-28A additionally exhibits anti-tumor activity, in part by enhancing IL-12 dependent anti-tumor CTL responses in vivo . In contrast, it is up-regulated in invasive bladder cancer where it promotes tumor cell migration.

Name: IFNL2,IL-28A,IL28A, IFNL2a, IFNL3a, IL-28A

Gen-ID: 282616

UniProt: Q8IZJ0