IGFBPI Protein (His tag)

Produktnummer ABIN7534341

Produktdetails

Target: IGFBPI (Insulin-Like Growth Factor Binding Protein 1 (IGFBPI))

Protein-Typ: Recombinant

Biologische Aktivität: Active

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses IGFBPI Protein ist gelabelt mit His tag.

Verwendungszweck: Active Recombinant Human IGFBP-1 Protein

Sequenz: APWQCAPCSA EKLALCPPVS ASCSEVTRSA GCGCCPMCAL PLGAACGVAT ARCARGLSCR ALPGEQQPLH ALTRGQGACV QESDASAPHA AEAGSPESPE STEITEEELL DNFHLMAPSE EDHSILWDAI STYDGSKALH VTNIKKWKEP CRIELYRVVE SLAKAQETSG EEISKFYLPN CNKNGFYHSR QCETSMDGEA GLCWCVYPWN GKRIPGSPEI RGDPNCQIYF NVQN

Spezifität: Ala26-Asn259

Reinheit: > 97 % by SDS-PAGE.

Sterilität: 0.22 μm filtered

Endotoxin-Niveau: < 0.1 EU/μg of the protein by LAL method.

Biological Activity Comment: Measured by its binding ability in a functional ELISA. Immobilized Recombinant Human IGFBP-1 at 5 μg/mL (100 μL/well) can bind Recombinant Human IGF1 with a linear range of 44-176 ng/mL.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.

Buffer: Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Store the lyophilized protein at -20°C to -80 °C for long term.
After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.

Antigendetails

Target: IGFBPI (Insulin-Like Growth Factor Binding Protein 1 (IGFBPI))

Andere Bezeichnung: IGFBP-1 (IGFBPI Produkte)

Synonyme: cb656 Protein, igfbp1 Protein, IGFBP-1 Protein, MGC68538 Protein, afbp Protein, ibp1 Protein, pp12 Protein, igf-bp25 Protein, higfbp-1 Protein, IGFBP1 Protein, LOC100223208 Protein, LOC100305121 Protein, AFBP Protein, IBP1 Protein, IGF-BP25 Protein, PP12 Protein, hIGFBP-1 Protein, IGFBA Protein, insulin like growth factor binding protein 1 Protein, insulin-like growth factor binding protein 1a Protein, insulin like growth factor binding protein 1 S homeolog Protein, insulin like growth factor binding protein 1 L homeolog Protein, insulin-like growth factor binding protein 1 Protein, IGFBP1 Protein, igfbp1a Protein, igfbp1.S Protein, igfbp1.L Protein, igfbp1 Protein, LOC100305121 Protein, Igfbp1 Protein

Hintergrund:

Description: The superfamily of insulin-like growth factor (IGF) binding proteins include the six high-affinity IGF binding proteins (IGFBP) and at least four additional low-affinity binding proteins referred to as IGFBP related proteins (IGFBP-rP). All IGFBP superfamily members are cysteine-rich proteins with conserved cysteine residues, which are clustered in the amino- and carboxy-terminal thirds of the molecule. IGFBPs modulate the biological activities of IGF proteins. Some IGFBPs may also have intrinsic bioactivity that is independent of their ability to bind IGF proteins. Post-transitional modifications of IGFBP, including glycosylation, phosphorylation and proteolysis, have been shown to modify the affinities of the binding proteins to IGF.

Name: AFBP, IBP1, IGF-BP25, PP12, hIGFBP-1,IGFBP1,IBP1,IGF-BP25,PP12,hIGFBP-1

Gen-ID: 3484

UniProt: P08833

Pathways: Myometrial Relaxation and Contraction, ER-Nucleus Signaling, Growth Factor Binding