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CLEC10A Protein (His tag)

CLEC10A Spezies: Human Wirt: HEK-293 Cells Recombinant > 90 % by SDS-PAGE.
Produktnummer ABIN7534241
  • Target Alle CLEC10A Proteine anzeigen
    CLEC10A (C-Type Lectin Domain Family 10, Member A (CLEC10A))
    Protein-Typ
    Recombinant
    Spezies
    • 12
    • 5
    • 1
    Human
    Quelle
    • 7
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    HEK-293 Cells
    Aufreinigungstag / Konjugat
    Dieses CLEC10A Protein ist gelabelt mit His tag.
    Verwendungszweck
    Recombinant Human CD301 Protein
    Sequenz
    QNSKFQRDLV TLRTDFSNFT SNTVAEIQAL TSQGSSLEET IASLKAEVEG FKQERQAGVS ELQEHTTQKA HLGHCPHCPS VCVPVHSEML LRVQQLVQDL KKLTCQVATL NNNASTEGTC CPVNWVEHQD SCYWFSHSGM SWAEAEKYCQ LKNAHLVVIN SREEQNFVQK YLGSAYTWMG LSDPEGAWKW VDGTDYATGF QNWKPGQPDD WQGHGLGGGE DCAHFHPDGR WNDDVCQRPY HWVCEAGLGQ TSQESH
    Spezifität
    Gln61-His316
    Reinheit
    > 90 % by SDS-PAGE.
    Sterilität
    0.22 μm filtered
    Endotoxin-Niveau
    < 1.0 EU/μg of the protein by LAL method.
    Top Product
    Discover our top product CLEC10A Protein
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
    Buffer
    Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Store the lyophilized protein at -20°C to -80 °C for long term.
    After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.
  • Target
    CLEC10A (C-Type Lectin Domain Family 10, Member A (CLEC10A))
    Andere Bezeichnung
    CD301 (CLEC10A Produkte)
    Synonyme
    CLEC10A Protein, CD301 Protein, CLECSF13 Protein, CLECSF14 Protein, HML Protein, HML2 Protein, MGL Protein, CD301a Protein, M-ASGP-BP-1 Protein, Mgl Protein, Mgl1 Protein, Mgll Protein, C-type lectin domain family 10 member A Protein, C-type lectin domain containing 10A Protein, C-type lectin domain family 10, member A Protein, LOC607405 Protein, CLEC10A Protein, Clec10a Protein
    Hintergrund

    Description: CLEC10A, also known as macrophage galactose/N-acetyl-galactosamine (GalNAc) specific lectin (MGL), CD301, DC-ASGPR, and HML, is a 40 kDa type II transmembrane glycoprotein that belongs to the C-type lectin family. C-type lectin family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. CLEC10A is expressed on macrophages and related cells of myeloid origins, particularly immature dendritic cells (DCs). CLEC10A plays a protective role against colitis by effectively inducing IL-10 production by colonic lamina propria macrophages in response to invading commensal bacteria.

    Name: CLEC10A,CD301,CLECSF13,CLECSF14,HML,HML2,MGL

    Gen-ID
    10462
    UniProt
    Q8IUN9
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