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ANGPTL7 Protein (His tag)

ANGPTL7 Spezies: Human Wirt: HEK-293 Cells Recombinant > 95 % by SDS-PAGE. Active
Produktnummer ABIN7534253
  • Target Alle ANGPTL7 Proteine anzeigen
    ANGPTL7 (Angiopoietin-Like 7 (ANGPTL7))
    Protein-Typ
    Recombinant
    Biologische Aktivität
    Active
    Spezies
    • 12
    • 2
    • 1
    Human
    Quelle
    • 9
    • 2
    • 1
    • 1
    • 1
    • 1
    HEK-293 Cells
    Aufreinigungstag / Konjugat
    Dieses ANGPTL7 Protein ist gelabelt mit His tag.
    Verwendungszweck
    Active Recombinant Human Angiopoietin-like 7/ANGPTL7 Protein
    Sequenz
    QKLSKHKTPA QPQLKAANCC EEVKELKAQV ANLSSLLSEL NKKQERDWVS VVMQVMELES NSKRMESRLT DAESKYSEMN NQIDIMQLQA AQTVTQTSAD AIYDCSSLYQ KNYRISGVYK LPPDDFLGSP ELEVFCDMET SGGGWTIIQR RKSGLVSFYR DWKQYKQGFG SIRGDFWLGN EHIHRLSRQP TRLRVEMEDW EGNLRYAEYS HFVLGNELNS YRLFLGNYTG NVGNDALQYH NNTAFSTKDK DNDNCLDKCA QLRKGGYWYN CCTDSNLNGV YYRLGEHNKH LDGITWYGWH GSTYSLKRVE MKIRPEDFKP
    Spezifität
    Gln27-Pro346
    Reinheit
    > 95 % by SDS-PAGE.
    Sterilität
    0.22 μm filtered
    Endotoxin-Niveau
    < 0.1 EU/μg of the protein by LAL method.
    Biological Activity Comment
    Measured by its binding ability in a functional ELISA. Immobilized Recombinant Human ANGPTL7 at 5 μg/mL (100 μL/well) can bind Recombinant Human LILRB4 with a linear range of 0.5-3.5 μg/mL.
    Top Product
    Discover our top product ANGPTL7 Protein
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
    Buffer
    Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Store the lyophilized protein at -20°C to -80 °C for long term.
    After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.
  • Target
    ANGPTL7 (Angiopoietin-Like 7 (ANGPTL7))
    Andere Bezeichnung
    Angiopoietin-like 7/ANGPTL7 (ANGPTL7 Produkte)
    Synonyme
    AngX Protein, CDT6 Protein, RP4-647M16.2 Protein, dJ647M16.1 Protein, MGC84421 Protein, zgc:101687 Protein, angiopoietin like 7 Protein, angiopoietin-like 7 Protein, angiopoietin like 7 S homeolog Protein, ANGPTL7 Protein, Angptl7 Protein, angptl7.S Protein, angptl7 Protein
    Hintergrund

    Description: Angiopoietin-like 7 (ANGPTL7), also known as Corneal-Derived Transcript 6 (CDT6), is a secreted glycoprotein that is structurally related to the angiopoietins. ANGPTL7 is expressed in the corneal stroma, trabecular meshwork, and sclera and is elevated in glaucoma aqueous humor. Its production is up regulated in trabecular meshwork cells by glucocorticoids and TGF-beta and in cartilage by TNF-alpha. Overexpression of ANGPTL7 in trabecular meshwork cells inhibits the production of collagen and proteoglycans . When overexpressed in tumor cells it promotes collagen and proteoglycan deposition but inhibits tumor xenograft progression and tumor angiogenesis.

    Name: ANGPTL7,AngX,CDT6,dJ647M16.1

    Gen-ID
    10218
    UniProt
    O43827
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