APLP1 Protein (His tag)

Produktnummer ABIN7535312

Produktdetails

Target: APLP1 (Amyloid beta (A4) Precursor-Like Protein 1 (APLP1))

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses APLP1 Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human APLP-1 Protein

Sequenz: SLAGGSPGAA EAPGSAQVAG LCGRLTLHRD LRTGRWEPDP QRSRRCLRDP QRVLEYCRQM YPELQIARVE QATQAIPMER WCGGSRSGSC AHPHHQVVPF RCLPGEFVSE ALLVPEGCRF LHQERMDQCE SSTRRHQEAQ EACSSQGLIL HGSGMLLPCG SDRFRGVEYV CCPPPGTPDP SGTAVGDPST RSWPPGSRVE GAEDEEEEES FPQPVDDYFV EPPQAEEEEE TVPPPSSHTL AVVGKVTPTP RPTDGVDIYF GMPGEISEHE GFLRAKMDLE ERRMRQINEV MREWAMADNQ SKNLPKADRQ ALNEHFQSIL QTLEEQVSGE RQRLVETHAT RVIALINDQR RAALEGFLAA LQADPPQAER VLLALRRYLR AEQKEQRHTL RHYQHVAAVD PEKAQQMRFQ VHTHLQVIEE RVNQSLGLLD QNPHLAQELR PQIQELLHSE HLGPSELEAP APGGSSEDKG GLQPPDSKDD TPMTLPKGST EQDAASPEKE KMNPLEQYER KVNASVPRGF PFHSSEIQRD ELAPAGTGVS RE

Spezifität: Ser39-Glu580

Reinheit: > 95 % by SDS-PAGE.

Sterilität: 0.22 μm filtered

Endotoxin-Niveau: <0.1EU/μg

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.

Buffer: Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Store the lyophilized protein at -20°C to -80°C for long term.|After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.

Antigendetails

Target: APLP1 (Amyloid beta (A4) Precursor-Like Protein 1 (APLP1))

Andere Bezeichnung: APLP-1 (APLP1 Produkte)

Synonyme: aplp Protein, MGC115336 Protein, APLP Protein, Aplp1_retired Protein, RGD1561211 Protein, amyloid beta precursor like protein 1 Protein, amyloid beta precursor like protein 1 L homeolog Protein, amyloid beta (A4) precursor-like protein 1 Protein, APLP1 Protein, aplp1.L Protein, aplp1 Protein, Aplp1 Protein

Hintergrund:

Description: APLP1, also known as amyloid-like protein 1, is a member of the highly conserved amyloid precursor protein gene family. APLP1 is a membrane-associated glycoprotein that is cleaved by secretases in a manner similar to amyloid beta A4 precursor protein cleavage. APLP1, together with APLP2, are important modulators of glucose. APLP1 may also play a role in synaptic maturation during cortical development. Alternatively spliced transcript variants encoding different isoforms have been described. APLP1 also is a mammalian homologue of amyloid precursor protein (APP). APP is a type I membrane protein that is genetically linked to Alzheimer's disease.

Name: APLP1,APLP

Gen-ID: 333

UniProt: P51693

Pathways: cAMP Metabolic Process